Bulletin of the Korean Chemical Society

  • 제32권2호
  • /
  • Pages.431-433
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  • 2011
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  • 0253-2964(pISSN)
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  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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Alginate-Microfibers Produced by Self-Assembly in Cell Culture Medium

  • Park, Jeong-Hui (Department of Nanobiomedical Science & WCU Research Center, Dankook University Graduate School) ;
  • Shin, Ueon-Sang (Department of Nanobiomedical Science & WCU Research Center, Dankook University Graduate School) ;
  • Kim, Hae-Won (Department of Nanobiomedical Science & WCU Research Center, Dankook University Graduate School)
  • 투고 : 2010.08.25
  • 심사 : 2010.11.23
  • 발행 : 2011.02.20
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초록

Alginate microfibers were fabricated by self assembly of alginate monomers exuded from alginate beads (~2 mm in diameter) containing calcium phosphate. Upon incubation of the beads in cell culture medium at $37^{\circ}C$ for a few days, fibers with a diameter of about $7{\mu}m$ started to sprout from the bead surface, and these grew up to about 10 mm in length, resulting in the beads being covered with fiber forests similar to chestnut bur. The combined system of the alginatebased microfiber forest and bead is considered to be useful as a novel 3-dimensional scaffold for cell culture and tisssue growth.

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참고문헌

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피인용 문헌

  1. Immunotoxicity of Copper Alginate Fibers in Guinea Pigs and Mice vol.144, pp.1-3, 2011, https://doi.org/10.1007/s12011-011-9133-7
  2. A novel method for producing bi-component thermo-regulating alginate fiber from phase change material microemulsion vol.90, pp.9, 2011, https://doi.org/10.1177/0040517519886075