The Korean Journal of Medicine

  • 제81권3호
  • /
  • Pages.403-407
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  • 2011
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  • 1738-9364(pISSN)
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  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
권호 표지

원발성 미만성 B세포 위림프종과 간세포암이 병발된 1예

Case of Synchronous Primary Gastric Diffuse Large B-Cell Lymphoma and Hepatocellular Carcinoma

  • 정민욱 (아주대학교 의과대학 내과학교실) ;
  • 이홍섭 (아주대학교 의과대학 내과학교실) ;
  • 송준하 (아주대학교 의과대학 내과학교실) ;
  • 김선미 (아주대학교 의과대학 내과학교실) ;
  • 김현경 (아주대학교 의과대학 내과학교실) ;
  • 이효정 (아주대학교 의과대학 내과학교실) ;
  • 정성현 (아주대학교 의과대학 내과학교실)
  • Jung, Min-Wook (Department of Internal Medicine, Ajou University School of Medicine) ;
  • Lee, Hong-Sub (Department of Internal Medicine, Ajou University School of Medicine) ;
  • Song, Jun-Ha (Department of Internal Medicine, Ajou University School of Medicine) ;
  • Kim, Sun-Mi (Department of Internal Medicine, Ajou University School of Medicine) ;
  • Kim, Hyun-Kyung (Department of Internal Medicine, Ajou University School of Medicine) ;
  • Lee, Hyo-Jung (Department of Internal Medicine, Ajou University School of Medicine) ;
  • Jung, Seong-Hyun (Department of Internal Medicine, Ajou University School of Medicine)
  • 발행 : 2011.09.01
⟨ 이전 논문 다음 논문 ⟩

초록

위에 발생하는 악성종양 중 원발성 위림프종은 상당히 드문편으로 동시에 간세포암이 병발한 경우는 매우 드물다. 본 증례는 원발성 위림프종과 간세포암의 병발로 진단된 46세 남자에 대한 보고로서 각각의 종양에 대하여 조직검사 및 면역조직화학 검사를 시행하여 진단하였다. 림프종에 대하여는 R-CHOP 항암화학요법(rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone)을 시행하여 완전관해를 하였고, 항암화학요법 중간에 간동맥 화학 색전술 및 간좌엽 절제술을 시행하여 간세포암에 대한 근치적 치료를 시행하였고, 현재 추적관찰 중이다.

Primary gastric lymphoma is relatively rare in the context of gastric malignancies. Synchronous primary gastric lymphoma and hepatocellular carcinoma (HCC) are even rarer. We report a case of synchronous primary gastric lymphoma and HCC in a 46-year-old man that appeared to be associated with hepatitis B virus infection. Pathologic examination and immunohistochemical analysis of gastric and liver specimens showed diffuse large B-cell lymphoma and HCC, respectively. The patient was initially treated for primary gastric lymphoma with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone) chemotherapy. During the chemotherapy interval, he was treated for HCC by transarterial chemoembolization (TACE) and laparoscopy-assisted left hemihepatectomy.

키워드

참고문헌

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