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OVARIAN TUMOR-ASSOCIATED CARCINOID HEART DISEASE PRESENTING AS SEVERE TRICUSPID REGURGITATION

  • Shin, Hong-Won (Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center) ;
  • Kim, Hyung-Seop (Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center) ;
  • Yoon, Hyuck-Jun (Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center) ;
  • Park, Hyoung-Seob (Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center) ;
  • Cho, Yun-Kyeong (Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center) ;
  • Nam, Chang-Wook (Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center) ;
  • Hur, Seung-Ho (Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center) ;
  • Kim, Yoon-Nyun (Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center) ;
  • Kim, Kwon-Bae (Division of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Medical Center)
  • 발행 : 2011.03.27

초록

Carcinoid heart disease is characterized by heart valve dysfunction as well as carcinoid symptomatology. We report a case of carcinoid heart disease associated with a primary ovarian tumor. A 60-year-old woman presented for dyspnea evaluation with a history of facial flushing, telangiectatic skin changes, and pitting edema of both lower extremities. Chest radiography showed cardiomegaly, and echocardiography revealed an isolated, severe tricuspid regurgitation without left-sided valvular dysfunction. The tricuspid leaflets were severely retracted and shortened, resulting in poor coaptation. Furthermore, mild pulmonary valve stenosis and moderate regurgitation were found along with this deformation. The 24-hour urine analysis revealed an increased level of 5-hydroxyindoleacetic acid, and an ovarian tumor was apparent on computed tomography images. The mass was surgically removed, and the patient was diagnosed as having a primary ovarian carcinoid tumor. She was treated with chemotherapy and regularly followed-up with supportive treatments, deferring surgical correction.

키워드

참고문헌

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피인용 문헌

  1. Resolution of Right-Sided Heart Failure Symptoms after Resection of a Primary Ovarian Carcinoid Tumor vol.41, pp.5, 2011, https://doi.org/10.14503/thij-13-3314
  2. Primary ovarian carcinoid: A report of two cases and a decade registry vol.28, pp.4, 2011, https://doi.org/10.1016/j.jnci.2016.06.003
  3. Pure primary ovarian carcinoid tumor with carcinoid syndrome and cervical carcinoma: A rare concoction of dual primary malignancies vol.64, pp.3, 2011, https://doi.org/10.4103/ijpm.ijpm_1379_20