The Korean Journal of Medicine

  • 제81권2호
  • /
  • Pages.262-265
  • /
  • 2011
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  • 1738-9364(pISSN)
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  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
권호 표지

전립선암에서 발생한 수막암종증 1예

A Case of Meningeal Carcinomatosis from Prostate Cancer

  • 서현웅 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 유승훈 (울산대학교 의과대학 강릉아산병원 신경외과학교실) ;
  • 장경희 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 이정화 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 최종수 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 강길현 (울산대학교 의과대학 강릉아산병원 병리학교실) ;
  • 오호석 (울산대학교 의과대학 강릉아산병원 내과학교실)
  • Seo, Hyun-Woong (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • You, Seung-Hoon (Department of Neurosurgery, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Jang, Kyeong-Hee (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Lee, Joung-Hwa (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Choi, Jong-Soo (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Kang, Gil-Hyun (Department of Pathology, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Oh, Ho-Suk (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine)
  • 발행 : 2011.08.01
⟨ 이전 논문 다음 논문 ⟩

초록

수막암종증은 암세포가 뇌수막에 침윤한 상태로 정의하는데 자기공명영상이 진단방법으로 쓰이기 전까지 진단이 용이하지 않았다. 또한 전립선암 환자에서 수막암종증이 생긴 경우는 매우 희귀하여 증례보고 형식으로 소수에서 보고되고 있는 실정이다. 내원 11년 전 전립선암으로 근치적 전립선 절제술을 받고 내원 4년 전 골전이로 항암치료를 받은 병력이 있는 환자로 경련을 주소로 내원하여 시행한 반복적인 뇌척수액 검사에서 세포진을 발견하지 못했지만 뇌척수액 전립선 특이항원 양성소견과 뇌 자기공명영상 소견으로 수막암종증을 진단하고 조직검사를 통해 확진하여 적극적인 치료로 생명연장을 할 수 있었던 사례를 경험하였기에 문헌고찰과 함께 보고한다.

Meningeal carcinomatosis in patients with prostate cancer is very rare. Recently, we experienced a case of meningeal carcinomatosis in a patient with prostate cancer. He had undergone a radical prostatectomy 11 years before presentation and had undergone chemotherapy 4 years before presentation due to bone metastases. This time, he visited the emergency department because of a seizure. Although cerebrospinal fluid (CSF) examinations did not reveal malignant cells, we diagnosed meningeal carcinomatosis based on positive CSF prostate-specific antigen and magnetic resonance imaging (MRI) findings. The diagnosis was confirmed pathologically. We treated the patient with whole brain radiotherapy and intrathecal chemotherapy. We report a case of prostate cancer with meningeal carcinomatosis with a literature review.

키워드

참고문헌

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