원본 기호잇기검사와 두 가지 한국판 기호잇기검사의 비교

Comparison between the Original Version of Trail Making Test with Two Korean-Trail Making Tests

  • 김현정 (분당서울대학교병원 뇌신경센터) ;
  • 백민재 (분당서울대학교병원 뇌신경센터) ;
  • 장영희 (분당서울대학교병원 신경과) ;
  • 장일미 (분당서울대학교병원 신경과) ;
  • 류희진 (건국대학교병원 신경과) ;
  • 김민영 (건국대학교병원 신경과) ;
  • 한설희 (건국대학교병원 신경과) ;
  • 김상윤 (분당서울대학교병원 신경과)
  • Kim, Hyun-Jung (Clinical Neuroscience Center, Seoul National University Bundang Hospital) ;
  • Baek, Min-Jae (Clinical Neuroscience Center, Seoul National University Bundang Hospital) ;
  • Chang, Young-Hee (Department of Neurology, Seoul National University Bundang Hospital) ;
  • Jang, Il-Mi (Department of Neurology, Seoul National University Bundang Hospital) ;
  • Ryu, Hui-Jin (Department of Neurology, Konkuk University Medical Center) ;
  • Kim, Min-Young (Department of Neurology, Konkuk University Medical Center) ;
  • Han, Seol-Heui (Department of Neurology, Konkuk University Medical Center) ;
  • Kim, Sang-Yun (Department of Neurology, Seoul National University Bundang Hospital)
  • 발행 : 2011.09.30

초록

Background: The Trail Making Test (TMT) is commonly used as a neuropsychological test in clinical practice. However, the B form of original TMT (TMT-OR-B) is limited to use in other countries because it is made up with English alphabets. Therefore, in this study, two versions of Korean TMT (TMT-K: TMT-Korean Letter-B and TMT-Korean Consonant-B) and TMT-OR-B were used to examine the cognitive function for the elderly people in Korea. The purpose of this study was to find which version of three TMT was more sensitive to discriminate the group of patients with cognitive impairment in Korea and to judge whether the TMT-K was necessary. Methods: Total 115 participants (subjective memory impairment: SMI; mild cognitive impairment: MCI; early stage of Alzheimer's disease: EAD) were tested in two vesrions of TMT-K and the TMT-OR-B. To analyze the sensitivity of these tests, we drew the receiver operating characteristics (ROC) curve and estimated area under the curve (AUC). Results: In the TMT-KL-B, it discriminated significantly between MCI and EAD (AUC=0.863) and SMI and EAD (AUC=0.917). In the TMT-OR-B, the sensitivity is relatively high in distinguishing among three groups (the AUC of SMI and MCI: 0.784; the AUC of MCI and EAD: 0.722; the AUC of SMI and EAD: 0.945). Conclusions: Consequently, the TMT-OR-B is useful for examining cognitive dysfunction of old people in Korea. However, the TMT-OR-B is more appropriate for the high-educated rather than the low-educated to differentiate normal cognitive aging from MCI or EAD.

키워드

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