Comparison between the Original Version of Trail Making Test with Two Korean-Trail Making Tests

원본 기호잇기검사와 두 가지 한국판 기호잇기검사의 비교

  • Kim, Hyun-Jung (Clinical Neuroscience Center, Seoul National University Bundang Hospital) ;
  • Baek, Min-Jae (Clinical Neuroscience Center, Seoul National University Bundang Hospital) ;
  • Chang, Young-Hee (Department of Neurology, Seoul National University Bundang Hospital) ;
  • Jang, Il-Mi (Department of Neurology, Seoul National University Bundang Hospital) ;
  • Ryu, Hui-Jin (Department of Neurology, Konkuk University Medical Center) ;
  • Kim, Min-Young (Department of Neurology, Konkuk University Medical Center) ;
  • Han, Seol-Heui (Department of Neurology, Konkuk University Medical Center) ;
  • Kim, Sang-Yun (Department of Neurology, Seoul National University Bundang Hospital)
  • 김현정 (분당서울대학교병원 뇌신경센터) ;
  • 백민재 (분당서울대학교병원 뇌신경센터) ;
  • 장영희 (분당서울대학교병원 신경과) ;
  • 장일미 (분당서울대학교병원 신경과) ;
  • 류희진 (건국대학교병원 신경과) ;
  • 김민영 (건국대학교병원 신경과) ;
  • 한설희 (건국대학교병원 신경과) ;
  • 김상윤 (분당서울대학교병원 신경과)
  • Published : 2011.09.30

Abstract

Background: The Trail Making Test (TMT) is commonly used as a neuropsychological test in clinical practice. However, the B form of original TMT (TMT-OR-B) is limited to use in other countries because it is made up with English alphabets. Therefore, in this study, two versions of Korean TMT (TMT-K: TMT-Korean Letter-B and TMT-Korean Consonant-B) and TMT-OR-B were used to examine the cognitive function for the elderly people in Korea. The purpose of this study was to find which version of three TMT was more sensitive to discriminate the group of patients with cognitive impairment in Korea and to judge whether the TMT-K was necessary. Methods: Total 115 participants (subjective memory impairment: SMI; mild cognitive impairment: MCI; early stage of Alzheimer's disease: EAD) were tested in two vesrions of TMT-K and the TMT-OR-B. To analyze the sensitivity of these tests, we drew the receiver operating characteristics (ROC) curve and estimated area under the curve (AUC). Results: In the TMT-KL-B, it discriminated significantly between MCI and EAD (AUC=0.863) and SMI and EAD (AUC=0.917). In the TMT-OR-B, the sensitivity is relatively high in distinguishing among three groups (the AUC of SMI and MCI: 0.784; the AUC of MCI and EAD: 0.722; the AUC of SMI and EAD: 0.945). Conclusions: Consequently, the TMT-OR-B is useful for examining cognitive dysfunction of old people in Korea. However, the TMT-OR-B is more appropriate for the high-educated rather than the low-educated to differentiate normal cognitive aging from MCI or EAD.

Keywords

References

  1. Rabin LA, Barr WB, Burton LA. Assessment practices of clinical neuropsychologists in the United States and Canada: a survey of INS, NAN, and APA Division 40 members. Arch ClinNeuropsycho 2005; 20: 33-65.
  2. Leitan LA., Wolfson D. A selective and critical review of neuropsychological deficits and the frontal lobes. Neuropsycho Rev 1994; 4: 161-98. https://doi.org/10.1007/BF01874891
  3. Leitan LA., Wolfson D. A selective and critical review of neuropsychological deficits and the frontal lobes. Neuropsycho Rev 1994; 4: 161-98. https://doi.org/10.1007/BF01874891
  4. Spreen O, Struss E. A compendium of neuropsychological tests: Administration, norms and commentary 2nded. New York: Oxford University 1998.
  5. Heun R, Papassotifopoulos A, Jennssen F. The validity of psychometric instruments for detection of dementia in the alderly general population, Int J Geriatr Psychiatry 1998; 13: 368-80. https://doi.org/10.1002/(SICI)1099-1166(199806)13:6<368::AID-GPS775>3.0.CO;2-9
  6. Kraybill ML, Larson EB, Tsuang DW, Teri, McCormick WC, Bowen JD, et al. Cognitive differences in dementia patients with autopsyverified AD, Lewy body pathology, or both. Neurology 2005; 28: 2069-73.
  7. Walker AJ, Meared S, Sacjdev PS, Brodaty H. The differentiation of mild frontotemporal dementia from Alzheimer's disease and healthy aging by neuropsychological tests. IntPsychogeriatr 2005; 17: 57-68. https://doi.org/10.1017/S1041610204000778
  8. Crowe SF. The differential contribution of mental tracking, cognitive flexibility, visual search, and motor speed to performance on part A and B of the Trail Making Test. J ClinPsychol 1998; 54: 585-91. https://doi.org/10.1002/(SICI)1097-4679(199808)54:5<585::AID-JCLP4>3.0.CO;2-K
  9. Anderson SV, Bigler ED, Blatter DD. Frontal lobe lesion, diffuse damage, and neuropsychological functioning in Traumatic Brain-Injured patients. J ClinExpNeuropsychol 1995; 17: 900-3. https://doi.org/10.1080/01688639508402438
  10. Stuss DT, Bisschop SM, Alexander MP, Levine B, Katz D, Izukawa D. The Trail Making Tests: A study in focal lesion patients. Psychol Assess 2001; 13: 230-9. https://doi.org/10.1037/1040-3590.13.2.230
  11. Seo EH, Lee DY, Kim KW, Lee JH, Jhoo JH, Youn JC, Choo IH, Ha J, Woo JI. A normative study of the Trail Making Test in Korean elders. In J Geriatr Psyhiatry 2006; 21: 844-52. https://doi.org/10.1002/gps.1570
  12. Lee HS. Development and Validation of Korean version of Trail Making test for Elderly persons. A master's thesis of Sungkgyunkwan University. 2006.
  13. Park M, Chey J. A normative study of the Modified Trail Making Test for elderly Korean people. J ClinPsychol 2003; 22: 247-59.
  14. Park JS, Kang YW, Yi HS, Kim YJ, Ma HI, Lee BC. Usefulness of the Korean Trail Making Test for the Elderly (K-TMT-e) in detecting the frontal lobe dysfunction. Dementia and Neurocognitive Disorders 2007; 6: 12-7.
  15. Lee A, Angela LJ, Maureen KO, Christine C, Robert CG, Robert AS. Trail Making Test errors in normal aging, mild cognitive impairment, and dementia. Arch Clin Neuropsycho 2008; 23: 129-37.
  16. Grober E, Hall CB, Lipton RB, Zonderman AB, Resninck SM, Kawas C. Memory impairment, executive dysfunction, and intellectual decline in preclinical Alzheimer's disease. JINS 2008; 14: 266-78.
  17. Chen P, Ratcliff G, Belle SH, Cauley JA, Dekosky ST, Ganguli M. Cognitive tests that best discriminate between presymptomatic AD and those who remain nondemented. Neurology 2002; 55: 1847-53.
  18. Morris JC. The clinical dementia rating (CDR): Current version and scoring rules. Neurology 1993; 43: 2412-4.
  19. Reisberg B, Ferris SH, De Leon MJ, Crook T. The global deterioration scale for assessment of primary degenerative dementia. Am J Psychiatry 1982; 139: 1136-9.
  20. Chin J, Oh KJ, Seo SW, Shin HY, Na DL. The Characteristics and Subtypes of Subjective Memory Impairment in Older Adults. Dement Neurocog Dis 2010; 9: 115-21.
  21. Peterson R. Mild cognitive impairment as a diagnostic entity. J Int Medic 2004; 256: 183-94. https://doi.org/10.1111/j.1365-2796.2004.01388.x
  22. MaKhann G, Drachman D, Folstein M, Katzaman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease report of the NINCDS-ADRDA work group under the auspices of department of health abd human services task force on Alzheimer's disease. Neourology 1984; 34: 939-44. https://doi.org/10.1212/WNL.34.7.939
  23. Reitan RM. The relation of the Trail Making Test to organic brain damage. J Consul Pshol 1995; 19: 393-4.
  24. Fossum B, Holmberg H, Reinvang I. Spatial and symbolic factors in performance on the Trail Making Test. Nueropsychol 1992; 6: 71-5. https://doi.org/10.1037/0894-4105.6.1.71
  25. Rossini ED, Karl MA. The Trail Making Test A and B: a technical note on structural nonequivalence. Percept Mot Skills 1994; 78: 625-6. https://doi.org/10.2466/pms.1994.78.2.625
  26. Arnett JA, Labovitz S. Effect of physical layout in performance of the Trail Making Test. Psychol Assess 1995; 7: 220-1. https://doi.org/10.1037/1040-3590.7.2.220
  27. Gaudino EA, Geisler MA, Squires NK. Construct validity of the Trail Making Test: what makes part B harder? J ClinExpNeuropsychol 1995; 17: 529-35. https://doi.org/10.1080/01688639508405143
  28. Ivnik RJ, Malec JF, Smith GE, Tangalos EG, Peterson RC. Neuropsychological tests' norms above age 55: COWAT, BNT, MAE Token, WRAT-R Reading, AMNART, STROOP, TMT, and JLO. CinNeuropsychol 1996; 10: 267-78.
  29. Tombaugh TN. Trail Making Test A and B: normative data stratified by age and education. Arch ClinNeuropsychol 2004; 19: 203-14. https://doi.org/10.1016/S0887-6177(03)00039-8