The Korean Journal of Medicine

  • 제81권4호
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  • Pages.455-457
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  • 2011
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  • 1738-9364(pISSN)
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  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
권호 표지

폐결핵과 급성호흡부전

Pulmonary Tuberculosis and Acute Respiratory Failure

  • 손장원 (한양대학교 의과대학 호흡기내과학교실)
  • Son, Jang-Won (Department of Internal Medicine, Hanyang University College of Medicine)
  • 발행 : 2011.10.01
⟨ 이전 논문 다음 논문 ⟩

초록

Active pulmonary TB including miliary TB is a rare primary cause of acute respiratory failure and ARDS. Therefore, little has been known about the clinical characteristics and outcomes of patients with ARDS caused by pulmonary TB. However, the incidence of TB in Korea remains in the relatively high range (90 cases per 100,000 persons in 2010), and high mortality rates (over 60%) have recently been reported in patients with ARF arising from TB. Poor prognostic factors have been evaluated are old age, delayed treatment, bad physiologic scores and combined sepsis. To improve high mortality in patients with acute respiratory failure caused by TB, further prospective studies for ventilator strategy and corticosteroid treatment are needed.

키워드

참고문헌

  1. Zahar JR, Azoulay E, Klement E, et al. Delayed treatment contributes to mortality in ICU patients with severe active pulmonary tuberculosis and acute respiratory failure. Intensive Care Med 2001;27:513-520. https://doi.org/10.1007/s001340000849
  2. Sharma SK, Mohan A, Banga A, Saha PK, Guntupalli KK. Predictors of development and outcome in patients with acute respiratory distress syndrome due to tuberculosis. Int J Tuberc Lung Dis 2006;10:429-435.
  3. Lee PL, Jerng JS, Chang YL, et al. Patient mortality of active pulmonary tuberculosis requiring mechanical ventilation. Eur Respir J 2003;22:141-147. https://doi.org/10.1183/09031936.03.00038703
  4. Ryu YJ, Koh WJ, Kang EH, et al. Prognostic factors in pulmonary tuberculosis requiring mechanical ventilation for acute respiratory failure. Respirology 2007;12:406-411. https://doi.org/10.1111/j.1440-1843.2006.01007.x
  5. Kim YJ, Pack KM, Jeong E, et al. Pulmonary tuberculosis with acute respiratory failure. Eur Respir J 2008;32:1625-1630. https://doi.org/10.1183/09031936.00070907
  6. Lee K, Kim JH, Lee JH, et al. Acute respiratory distress syndrome caused by miliary tuberculosis: a multicentre survey in South Korea. Int J Tuberc Lung Dis 2011;15:1099-1103. https://doi.org/10.5588/ijtld.10.0557
  7. Kim TO, Kang HW, Chi SY, et al. Mortality and prognostic factors in acute respiratory distress syndrome due to tuberculosis. Korean J Med 2011;81:458-463.
  8. Bernard GR, Artigas A, Brigham KL, et al. The American- European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994;149(3 Pt 1):818-824. https://doi.org/10.1164/ajrccm.149.3.7509706
  9. Levy H, Kallenbach JM, Feldman C, Thorbum JR, Abramowitz JA. Acute respiratory failure in active tuberculosis. Crit Care Med 1987;15:221-225. https://doi.org/10.1097/00003246-198703000-00008
  10. Steinberg KP, Hudson LD, Goodman RB, et al. Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med 2006;354:1671-1684. https://doi.org/10.1056/NEJMoa051693