The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
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A study on the correlation between quality of life and disease severity in adult patients with atopic dermatitis

성인 아토피 피부염 환자의 삶의 질과 중증도에 대한 상관 연구

  • 김남권 (원광대학교 한의과대학 안이비인후피부과학교실) ;
  • 이동효 (원광대학교 한의과대학 안이비인후피부과학교실) ;
  • 조가원 (원광대학교 한의과대학 안이비인후피부과학교실) ;
  • 문효 (원광대학교 한의과대학 안이비인후피부과학교실) ;
  • 서은성 (원광대학교 한의과대학 안이비인후피부과학교실)
  • Received : 2011.10.05
  • Accepted : 2011.12.09
  • Published : 2011.12.25
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Abstract

Objective : The purpose of this clinical research was to analyze the correlation between disease severity and disease specific quality of life adjusted by general quality of life measure in adult patients with atopic dermatitis attending Wonkwang Univ. Sanbon Oriental Medical Center. Methods : A total of 35 patients participated in atopic dermatitis clinical trial from June 1st, 2010 to June 30th, 2011 were included in this study. SCORing Atopic Dermatitis(SCORAD) index, Dermatologic Life Quality Index(DLQI), Health Utility Index III(HUI-III) and EuroQoL 5-Dimension(EQ-5D) have been estimatied. Baseline statistical analysis and normality test were done by using Student t-test, Shapiro-Wilk test and ladder test. Pearson analysis and Spearman analysis were conducted to examined the correlation of each variables. Hierachial regression analysis was performed using related variables. Statistical significance was achieved if the probability was less than 5%. Results : There were statistically significance between DLQI and SCORAD index, and also between DLQI and EQ-5D. However there was no significant between DLQI and HUI-III. In the hierachial regression analysis, after adjusting for demographic variables (gender, age) and general quality of life (EQ-5D), SCORAD index significantly predict the intensity of disease specific quality of life (DLQI). Conclusions : We confirmed the correlation between SCORAD index and DLQI, and developed the inference for regression equation of DLQI using SCORAD index, EQ-5D and demographic variables.

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References

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