DOI QR코드

DOI QR Code

STRESS CARDIOMYOPATHY COMPLICATED BY LEFT VENTRICULAR THROMBI AND CEREBRAL INFARCTIONS IN A PATIENT WITH ESSENTIAL THROMBOCYTHEMIA

  • Hwang, Seung-Hwan (Department of Cardiovascular Medicine, Chonnam National University Hospital, The Research Institute of Medical Sciences, Chonnam National University) ;
  • Kim, Kye-Hun (Department of Cardiovascular Medicine, Chonnam National University Hospital, The Research Institute of Medical Sciences, Chonnam National University) ;
  • Yoon, Hyun-Ju (Department of Cardiovascular Medicine, Chonnam National University Hospital, The Research Institute of Medical Sciences, Chonnam National University) ;
  • Hong, Young-Joon (Department of Cardiovascular Medicine, Chonnam National University Hospital, The Research Institute of Medical Sciences, Chonnam National University) ;
  • Kim, Ju-Han (Department of Cardiovascular Medicine, Chonnam National University Hospital, The Research Institute of Medical Sciences, Chonnam National University) ;
  • Ahn, Young-Keun (Department of Cardiovascular Medicine, Chonnam National University Hospital, The Research Institute of Medical Sciences, Chonnam National University) ;
  • Jeong, Myung-Ho (Department of Cardiovascular Medicine, Chonnam National University Hospital, The Research Institute of Medical Sciences, Chonnam National University) ;
  • Cho, Jeong-Gwan (Department of Cardiovascular Medicine, Chonnam National University Hospital, The Research Institute of Medical Sciences, Chonnam National University) ;
  • Park, Jong-Chun (Department of Cardiovascular Medicine, Chonnam National University Hospital, The Research Institute of Medical Sciences, Chonnam National University) ;
  • Kang, Jung-Chaee (Department of Cardiovascular Medicine, Chonnam National University Hospital, The Research Institute of Medical Sciences, Chonnam National University)
  • Published : 2011.06.27

Abstract

The prognosis of stress induced cardiomyopathy (SCMP) is generally known to be excellent, however, several fatal complications such as cardiac rupture and left ventricular (LV) thrombosis with subsequent embolic complications have been described. We report a rare case of SCMP complicated by LV thrombosis and multiple cerebral infarctions in a patient with essential thrombocythemia. After intravenous anticoagulation with heparin and general managements for heart failure and cerebral infarctions, her neurologic symptoms and the wall motion abnormalities of the LV apex were improved, and the thrombus was disappeared on follow-up echocardiography.

Keywords

References

  1. Abraham J, Mudd JO, Kapur NK, Klein K, Champion HC, Wittstein IS. Stress cardiomyopathy after intravenous administration of catecholamines and beta-receptor agonists. J Am Coll Cardiol 2009;53:1320-5.
  2. Shin SK, Jin SA, Park YK, Park JH. A case of acute ST-segment elevation myocardial infarction mimicking stress induced cardiomyopathy; demonstration of typical echocardiographic finding correlated with unusual distribution of left anterior descending coronary artery. J Cardiovasc Ultrasound 2010;18:101-3.
  3. Steurer M, Gastl G, Jedrzejczak WW, Pytlik R, Lin W, Schlogl E, Gisslinger H. Anagrelide for thrombocytosis in myeloproliferative disorders: a prospective study to assess efficacy and adverse event profile. Cancer 2004;101:2239-46.
  4. Mazzucconi MG, Redi R, Bernasconi S, Bizzoni L, Dragoni F, Latagliata R, Santoro C, Mandelli F. A long-term study of young patients with essential thrombocythemia treated with anagrelide. Haematologica 2004;89:1306-13.
  5. Birgegard G. Long-term management of thrombocytosis in essential thrombocythaemia. Ann Hematol 2009;88:1-10. https://doi.org/10.1007/s00277-008-0531-7
  6. de Gregorio C. Cardioembolic outcomes in stress-related cardiomyopathy complicated by ventricular thrombus: a systematic review of 26 clinical studies. Int J Cardiol 2010;141:11-7.
  7. Haghi D, Papavassiliu T, Heggemann F, Kaden JJ, Borggrefe M, Suselbeck T. Incidence and clinical significance of left ventricular thrombus in tako-tsubo cardiomyopathy assessed with echocardiography. QJM 2008;101:381-6.
  8. Mitsuma W, Kodama M, Ito M, Kimura S, Tanaka K, Hoyano M, Hirono S, Aizawa Y. Thromboembolism in Takotsubo cardiomyopathy. Int J Cardiol 2010;139:98-100.
  9. Donohue D, Movahed MR. Clinical characteristics, demographics and prognosis of transient left ventricular apical ballooning syndrome. Heart Fail Rev 2005;10:311-6.
  10. Baker KM, Hess CE, Ayers CR, Johns DW, Mentzer RM, Wellsons HA, Taylor GJ, Martin RP. Left ventricular mural thrombus in a patient with thrombocytosis and agnogenic myeloid metaplasia. Arch Intern Med 1981;141:1527-9.

Cited by

  1. Takotsubo Syndrome: Clinical Features, Pathogenesis, Treatment, and Relationship with Cerebrovascular Diseases vol.18, pp.5, 2011, https://doi.org/10.1007/s11910-018-0833-7