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ARTERIAL-CARDIAC INTERACTION: THE CONCEPT AND IMPLICATIONS

  • Shim, Chi-Young (Cardiology Division, Severance Cardiovascular Hospital, Yonsei University College of Medicine)
  • Published : 2011.06.27

Abstract

Vascular stiffening of the large arteries is a common feature of human aging. Increased aortic stiffness with age may contribute to pathological changes in the left ventricle and this can induce ventricular stiffening. Vascular-ventricular stiffening combined with abnormal arterial-cardiac interaction is considered an important pathophysiology of heart failure with a preserved ejection fraction. Here, I briefly review the concept and implications of arterial-cardiac interaction and this will pave the way to understanding and controlling heart failure with a preserved ejection fraction, which is more prevalent in the elderly.

Keywords

References

  1. Sunagawa K, Maughan WL, Burkhoff D, Sagawa K. Left ventricular interaction with arterial load studied in isolated canine ventricle. Am J Physiol 1983;245:H773-80.
  2. Starling MR. Left ventricular-arterial coupling relations in the normal human heart. Am Heart J 1993;125:1659-66.
  3. Kass DA. Age-related changes in venticular-arterial coupling: pathophysiologic implications. Heart Fail Rev 2002;7:51-62.
  4. Kass DA. Ventricular arterial stiffening: integrating the pathophysiology. Hypertension 2005;46:185-93.
  5. O'Rourke MF, Hashimoto J. Mechanical factors in arterial aging: a clinical perspective. J Am Coll Cardiol 2007;50:1-13.
  6. O'Rourke MF. Arterial aging: pathophysiological principles. Vasc Med 2007;12:329-41.
  7. Smulyan H, Asmar RG, Rudnicki A, London GM, Safar ME. Comparative effects of aging in men and women on the properties of the arterial tree. J Am Coll Cardiol 2001;37:1374-80.
  8. Choi CU, Kim EJ, Kim SH, Shin SY, Choi UJ, Kim JW, Lim HE, Rha SW, Park CG, Seo HS, Oh DJ. Differing effects of aging on central and peripheral blood pressures and pulse wave velocity: a direct intraarterial study. J Hypertens 2010;28:1252-60.
  9. McEniery CM, Yasmin, Hall IR, Qasem A, Wilkinson IB, Cockcroft JR; ACCT Investigators. Normal vascular aging: differential effects on wave reflection and aortic pulse wave velocity: the Anglo-Cardiff Collaborative Trial (ACCT). J Am Coll Cardiol 2005;46:1753-60.
  10. Antonini-Canterin F, Carerj S, Di Bello V, Di Salvo G, La Carrubba S, Vriz O, Pavan D, Balbarini A, Nicolosi GL; Research Group of the Italian Society of Cardiovascular Echography (SIEC). Arterial stiffness and ventricular stiffness: a couple of diseases or a coupling disease? A review from the cardiologist's point of view. Eur J Echocardiogr 2009;10:36-43.
  11. Laurent S, Cockcroft J, Van Bortel L, Boutouyrie P, Giannattasio C, Hayoz D, Pannier B, Vlachopoulos C, Wilkinson I, Struijker-Boudier H; European Network for Non-invasive Investigation of Large Arteries. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J 2006;27:2588-605.
  12. Kelly R, Hayward C, Avolio A, O'Rourke M. Noninvasive determination of age-related changes in the human arterial pulse. Circulation 1989; 80:1652-9.
  13. Benetos A, Thomas F, Joly L, Blacher J, Pannier B, Labat C, Salvi P, Smulyan H, Safar ME. Pulse pressure amplification a mechanical biomarker of cardiovascular risk. J Am Coll Cardiol 2010;55:1032-7.
  14. Nijdam ME, Plantinga Y, Hulsen HT, Bos WJ, Grobbee DE, van der Schouw YT, Bots ML. Pulse pressure amplification and risk of cardiovascular disease. Am J Hypertens 2008;21:388-92.
  15. Hirai T, Sasayama S, Kawasaki T, Yagi S. Stiffness of systemic arteries in patients with myocardial infarction. A noninvasive method to predict severity of coronary atherosclerosis. Circulation 1989;80:78-86.
  16. Mottram PM, Haluska BA, Leano R, Carlier S, Case C, Marwick TH. Relation of arterial stiffness to diastolic dysfunction in hypertensive heart disease. Heart 2005;91:1551-6.
  17. Weber T, Auer J, O'Rourke MF, Punzengruber C, Kvas E, Eber B. Prolonged mechanical systole and increased arterial wave reflections in diastolic dysfunction. Heart 2006;92:1616-22.
  18. Shim CY, Park S, Choi D, Yang WI, Cho IJ, Choi EY, Chung N, Ha JW. Sex differences in central hemodynamics and their relationship to left ventricular diastolic function. J Am Coll Cardiol 2011;57:1226-33.
  19. Borlaug BA. Sex, load, and relaxation: are women more susceptible to loaddependent diastolic dysfunction? J Am Coll Cardiol 2011;57:1234-6 https://doi.org/10.1016/j.jacc.2010.10.033
  20. Myhre ES, Johansen A, Piene H. Optimal matching between canine left ventricle and afterload. Am J Physiol 1988;254:H1051-8.
  21. Elzinga G, Westerhof N. Matching between ventricle and arterial load. An evolutionary process. Circ Res 1991;68:1495-500.
  22. Devereux RB, Alonso DR, Lutas EM, Gottlieb GJ, Campo E, Sachs I, Reichek N. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardiol 1986;57:450-8.
  23. Kelly RP, Ting CT, Yang TM, Liu CP, Maughan WL, Chang MS, Kass DA. Effective arterial elastance as index of arterial vascular load in humans. Circulation 1992;86:513-21.
  24. Chen CH, Nakayama M, Nevo E, Fetics BJ, Maughan WL, Kass DA. Coupled systolic-ventricular and vascular stiffening with age: implications for pressure regulation and cardiac reserve in the elderly. J Am Coll Cardiol 1998;32:1221-7.
  25. Nitenberg A, Loiseau A, Antony I. Left ventricular mechanical efficiency in hypertensive patients with and without increased myocardial mass and with normal pump function. Am J Hypertens 2001;14:1231-8.
  26. Asanoi H, Kameyama T, Ishizaka S, Miyagi K, Sasayama S. Ventriculoarterial coupling during exercise in normal human subjects. Int J Cardiol 1992;36:177-86.
  27. Najjar SS, Schulman SP, Gerstenblith G, Fleg JL, Kass DA, O'Connor F, Becker LC, Lakatta EG. Age and gender affect ventricular-vascular coupling during aerobic exercise. J Am Coll Cardiol 2004;44:611-7.

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