The Korean journal of internal medicine

The Korean Association of Internal Medicine (대한내과학회)
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Topical Steroids to Treat Granulomatous Mastitis: A Case Report

  • Altintoprak, Fatih (Department of General Surgery, Sakarya University Faculty of Medicine)
  • Published : 2011.09.01
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Abstract

Idiopathic granulomatous mastitis (IGM) is a rare and chronic benign disease of the breast. Histologically, the disease presents as an intense inflammatory reaction with non-caseated granulomas that are the characteristic symptom of the disease. No consensus exists on the best treatment modality for this disease. In this report, we present a patient with granulomatous mastitis who was treated successfully with low-dose oral and topical steroids. Our aim here is to discuss various approaches for IGM in view of the literature and present treatment with topical steroids, which has not been reported.

Keywords

References

  1. Kessler E, Wolloch Y. Granulomatous mastitis: a lesion clinically simulating carcinoma. Am J Clin Pathol 1972;58:642-646. https://doi.org/10.1093/ajcp/58.6.642
  2. Lai EC, Chan WC, Ma TK, Tang AP, Poon CS, Leong HT. The role of conservative treatment in idiopathic granulomatous mastitis. Breast J 2005;11:454-456. https://doi.org/10.1111/j.1075-122X.2005.00127.x
  3. Su FH, Liu SC, Suen JH, Chen DS, Sister Mary Ann Lou. Idiopathic granulomatous mastitis: a case successfully treated with a minimum dose of a steroid. Chang Gung Med J 2005;28:431-435.
  4. Asoglu O, Ozmen V, Karanlik H, et al. Feasibility of surgical management in patients with granulomatous mastitis. Breast J 2005;11:108-114. https://doi.org/10.1111/j.1075-122X.2005.21576.x
  5. Kim J, Tymms KE, Buckingham JM. Methotrexate in the management of granulomatous mastitis. ANZ J Surg 2003;73:247-249. https://doi.org/10.1046/j.1445-1433.2002.02564.x
  6. Lee JH, Oh KK, Kim EK, Kwack KS, Jung WH, Lee HK. Radiologic and clinical features of idiopathic granulomatous lobular mastitis mimicking advanced breast cancer. Yonsei Med J 2006;47:78-84. https://doi.org/10.3349/ymj.2006.47.1.78
  7. DeHertogh DA, Rossof AH, Harris AA, Economou SG. Prednisone management of granulomatous mastitis. N Engl J Med 1980;303:799-800. https://doi.org/10.1056/NEJM198010023031406
  8. Maffini F, Baldini F, Bassi F, Luini A, Viale G. Systemic therapy as a first choice treatment for idiopathic granulomatous mastitis. J Cutan Pathol 2009;36:689-691. https://doi.org/10.1111/j.1600-0560.2008.01102.x
  9. Buys LM. Treatment options for atopic dermatitis. Am Fam Physician 2007;75:523-528.
  10. Hanifin J, Gupta AK, Rajagopalan R. Intermittent dosing of fluticasone propionate cream for reducing the risk of relapse in atopic dermatitis patients. Br J Dermatol 2002;147:528-537. https://doi.org/10.1046/j.1365-2133.2002.05006.x

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  1. Effect of Topical Steroid Treatment on Idiopathic Granulomatous Mastitis: Clinical and Radiologic Evaluation vol.20, pp.6, 2011, https://doi.org/10.1111/tbj.12335
  2. Topical Steroids Are Effective in the Treatment of Idiopathic Granulomatous Mastitis vol.39, pp.11, 2011, https://doi.org/10.1007/s00268-015-3147-9
  3. Is surgical excision necessary for the treatment of Granulomatous lobular mastitis? vol.17, pp.1, 2011, https://doi.org/10.1186/s12905-017-0412-0
  4. The evaluation of the efficacy of local steroid administration in idiopathic granulomatous mastitis: The preliminary results vol.26, pp.2, 2011, https://doi.org/10.1111/tbj.13588
  5. Idiopathic granulomatous mastitis: case series and clinical review vol.51, pp.11, 2021, https://doi.org/10.1111/imj.15112