The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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A Case of Candida Parapsilosis Infectious Arthritis in a Patient with Enteropathic Arthritis and Ulcerative Colitis

장병증성 관절염에서 발생한 Candida Parapsilosis에 의한 감염성 관절염 1예

  • Park, Hee-Jin (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Jung, Se-Jin (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Oh, Tak-Geun (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Seok, Han-Nah (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Lee, Sang-Won (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Park, Yong-Beom (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Lee, Soo-Kon (Department of Internal Medicine, Yonsei University College of Medicine)
  • 박희진 (연세대학교 의과대학 내과학교실) ;
  • 정세진 (연세대학교 의과대학 내과학교실) ;
  • 오탁근 (연세대학교 의과대학 내과학교실) ;
  • 석한나 (연세대학교 의과대학 내과학교실) ;
  • 이상원 (연세대학교 의과대학 내과학교실) ;
  • 박용범 (연세대학교 의과대학 내과학교실) ;
  • 이수곤 (연세대학교 의과대학 내과학교실)
  • Published : 2011.12.01
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Abstract

Infectious arthritis is an important medical emergency with high morbidity. The most frequent causative organism of infectious arthritis is Staphylococcus aureus, and Candida is an uncommon pathogen. Candida arthritis has been reported to occur in seriously ill or immunocompromised patients and neonates. We report the first case of C. parapsilosis arthritis in a patient with ulcerative colitis. A 52-year-old woman was diagnosed with ulcerative colitis 1 year previously and took balsalazide. Pain and swelling in the right knee joint developed 6 months after diagnosis. She was diagnosed with enteropathic arthritis associated with ulcerative colitis and took methotrexate, sulfasalazine, and prednisolone for 3 months, but the symptoms did not improve. We finally diagnosed her with infectious C. parapsilosis arthritis by culturing the synovial fluid. The patient received amphotericin B for 6 weeks and underwent arthroscopic synovectomy. She finally experienced improvement of inflammation in the right knee joint.

장병증성 관절염으로 면역 억제제 치료를 받은 환자에서 반복적인 활액 천자 및 스테로이드 주사를 받은 후, C. parapsilosis에 의한 진균 감염성 관절염을 처음으로 경험하였기에, 이에 대해 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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