대한치매학회지 (Dementia and Neurocognitive Disorders)

대한치매학회 (Korean Dementia Association)
권호 표지

인지기능장애 노인환자에서 보호자용 노인우울검사의 유용성

A Usefulness of Caregiver Version of Geriatric Depression Scale in the Elderly Patients with Cognitive Dysfunction

  • 손효정 (고려대학교 노인건강연구소) ;
  • 임혜원 (고려대학교 노인건강연구소) ;
  • 김지선 (고려대학교 의과대학 신경과학교실) ;
  • 이성욱 (고려대학교 의과대학 신경과학교실) ;
  • 이혜미 (고려대학교 의과대학 신경과학교실) ;
  • 권도영 (고려대학교 노인건강연구소) ;
  • 박문호 (고려대학교 노인건강연구소) ;
  • 한창수 (고려대학교 노인건강연구소) ;
  • 박건우 (고려대학교 노인건강연구소) ;
  • 정인과 (고려대학교 의과대학 정신과학교실)
  • Sohn, Hyojeong (Geriatric Health Clinic and Research Institute, Korea University) ;
  • Yim, Hyewon (Geriatric Health Clinic and Research Institute, Korea University) ;
  • Kim, Jisun (Department of Neurology, Korea University Medical College) ;
  • Lee, Sungwoog (Department of Neurology, Korea University Medical College) ;
  • Lee, Hyemi (Department of Neurology, Korea University Medical College) ;
  • Kwon, Do-Young (Geriatric Health Clinic and Research Institute, Korea University) ;
  • Park, Moon Ho (Geriatric Health Clinic and Research Institute, Korea University) ;
  • Han, Changsu (Geriatric Health Clinic and Research Institute, Korea University) ;
  • Park, Kun-Woo (Geriatric Health Clinic and Research Institute, Korea University) ;
  • Jung, In-Kwa (Department of Psychiatry, Korea University Medical College)
  • 발행 : 2011.03.31
⟨ 이전 논문 다음 논문 ⟩

초록

Background: It was difficult to obtain the elderly patients' own report of their depressive symptoms, who had cognitive dysfunction. This study was aimed to evaluate the clinical usefulness of the collateral source version of elderly depression scale and to examine its correlation with patient version of elderly depression scale in the elderly patients with cognitive dysfunction. Methods: Thirty five elderly subjects with mild cognitive impairment (MCI), 32 elderly subjects with probable Alzheimer's disease (AD) according to the National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) criteria and 19 controls with subjective memory impairment with normal cognition completed the Korean form of geriatric depression scale (KGDS) and the collateral source version of KGDS (CS-KGDS). All subjects were also evaluated using the Korean version of the Mini-Mental Status Examination (K-MMSE) and the Clinical Dementia Rating (CDR). Results: There was no significant correlation between the KGDS and the CS-KGDS (r=0.160, p>0.05). The CS-KGDS was significant correlated with the K-MMSE (r=-0.272, p=0.001). The CS-KGDS was assessed more severely in AD group than in control and MCI groups (F[2,82]=10.60, p<0.001). The mean difference between the KGDS and the CS-KGDS was 6.44${\pm}$9.01 (paired t=-6.630, p<0.001). There was more difference between the KGDS and the CS-KGDS according to the severity of cognitive dysfunction. Conclusions: Although the CS-KGDS could be a useful tool for the elderly depressive symptom, it seemed to have some limitations to evaluate the elderly with dementia.

키워드

참고문헌

  1. Reifler BV. Diagnosing Alzheimer's disease in the presence of mixed cognitive and affective symptoms. Int Psychogeriatr 1997; 9(Suppl 1): 59-64. https://doi.org/10.1017/S1041610297004705
  2. Kim SY. Depression in dementia. Dementia Neurocog Disorders 2004; 3: 18-23.
  3. Jung IK, Kwak DI, Joe SH, Lee HS. A study of standardization of Korean form of geriatric depression scale (KGDS). Korean Geriatr Psychiatry 1997; 1: 61-72.
  4. Lee HS, You YS, Han JS, Kwak DI, Jung IK. A study of validity of collateral source version of Korean form of geriatric depression scale (CS-KGDS). Korean Geriatr Psychiatry 1998; 2: 187-96.
  5. Teri L, Wagner AW. Assessment of depression in patients with Alzheimer's disease: concordance among informants. Psychol Aging 1991; 6: 280-5. https://doi.org/10.1037/0882-7974.6.2.280
  6. Jung IK, Kwak DI, Shin DK, Lee MS, Lee HS, Kim JY. A reliability and validity study of geriatric depression scale. J Korean Neuropsychiatr Assoc 1997; 36: 103-12.
  7. Roberts RE. Reliability of the CES-D Scale in different ethnic contexts. Psychiatry Res 1980; 2: 125-34. https://doi.org/10.1016/0165-1781(80)90069-4
  8. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23: 56-62. https://doi.org/10.1136/jnnp.23.1.56
  9. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry 1961; 4: 561-71. https://doi.org/10.1001/archpsyc.1961.01710120031004
  10. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC: American Psychiatric Press, 1994.
  11. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984; 34: 939-44. https://doi.org/10.1212/WNL.34.7.939
  12. Petersen RC. Mild cognitive impairment as a diagnostic entity. J Intern Med 2004; 256: 183-94. https://doi.org/10.1111/j.1365-2796.2004.01388.x
  13. Yesavage JA. Geriatric Depression Scale. Psychopharmacol Bull 1988; 24: 709-11.
  14. Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 1982; 17: 37-49. https://doi.org/10.1016/0022-3956(82)90033-4
  15. Kang Y, Na DL, Hahn S. A validity study on the Korean Mini-mental State Examination (K-MMSE) in dementia patients. J Korean Neurol Assoc 1997; 15: 300-8.
  16. Choi SH, Na DL, Lee BH, Hahm DS, Jeong JH, Yoon SJ, et al. Estimating the Validity of the Korean Version of Expanded Clinical Dementia Rating (CDR) Scale. J Korean Neurol Assoc 2001; 19: 585-91.
  17. Campbell MJ, Machin D, Walters SJ. Medical statistics: a textbook for the health sciences. 4th ed. Chichester: John Wiley & Sons, 2007.
  18. Cohen J. Statistical power analysis for behavioral sciences. 2nd ed. New Jersey: Lawrence Earlbaum, 1988.
  19. Nitcher RL, Burke WJ, Roccaforte WJ, Wengel SP. A collateral source version of the geriatric depression rating scale. Am J Geriatr Psychiatry 1993; 1: 143-52. https://doi.org/10.1097/00019442-199300120-00007
  20. Burke WJ, Rangwani S, Roccaforte WH, Wengel SP, Conley DM. The reliability and validity of the collateral source version of the Geriatric Depression Rating Scale administered by telephone. Int J Geriatr Psychiatry 1997; 12: 288-94. https://doi.org/10.1002/(SICI)1099-1166(199703)12:3<288::AID-GPS474>3.0.CO;2-1
  21. Burke WJ, Roccaforte WH, Wengel SP, McArthur-Miller D, Folks DG, Potter JF. Disagreement in the reporting of depressive symptoms between patients with dementia of the Alzheimer type and their collateral sources. Am J Geriatr Psychiatry 1998; 6: 308-19. https://doi.org/10.1097/00019442-199811000-00006
  22. Teri L, Truax P. Assessment of depression in dementia patients: association of caregiver mood with depression ratings. The Gerontologist 1994; 34: 231-4. https://doi.org/10.1093/geront/34.2.231