Clinical Endoscopy

The Korean Society of Gastrointestinal Endoscopy (대한소화기내시경학회)
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A Case of Neuroendocrine Carcinoma of the Gallbladder That Was Diagnosed by Endoscopy

내시경을 통해 진단된 담낭 신경내분비암 1예

  • Lee, Hyon-A (Department of Internal Medicine, Kangbuk Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Hong-Joo (Department of Internal Medicine, Kangbuk Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Jung, Mi-Yeon (Department of Internal Medicine, Kangbuk Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Shin, Dong-Seok (Department of Internal Medicine, Kangbuk Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • 이현아 (성균관대학교 의과대학 강북삼성병원 내과학교실) ;
  • 김홍주 (성균관대학교 의과대학 강북삼성병원 내과학교실) ;
  • 정미연 (성균관대학교 의과대학 강북삼성병원 내과학교실) ;
  • 신동석 (성균관대학교 의과대학 강북삼성병원 내과학교실)
  • Published : 2011.06.30
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Abstract

Neuroendocrine carcinomas mostly occur in the gastrointestinal tract, lung and pancreas. The gallbladder is an uncommon organ for a neuroendocrine carcinoma and it is difficult to diagnose before gallbladder surgery. Owing to its rare occurrence its natural course and treatment are not definitely established. A 71-year-old woman was hospitalized with intermittent abdominal pain and nausea. Abdominal computed tomography showed multiple masses of the gallbladder obstructing the biliary tract. From endoscopic ultrasonography we suspected carcinoma of the gallbladder that was infiltrating a common bile duct. A biopsy was taken using endoscopic retrograde cholangiopancreatography (ERCP) and the mass was diagnosed as a neuroendocrine carcinoma of the gallbladder. Here we report a case of a neuroendocrine carcinoma of the gallbladder confirmed by endoscopic biopsy, and provide a review of the literature.

신경내분비종양은 주로 위장관, 폐와 췌장에 발생한다. 담낭의 원발성 신경내분비종양은 매우 드물게 발생하고 수술 전 진단이 어려운 것으로 알려져 있으며 발생빈도가 매우 낮아서 아직까지 자연경과 및 치료에 대해 확실히 정립되어 있지 않다. 71세 여자가 간헐적 복통과 오심 증상으로 내원하여 복부 CT에서 담관 폐쇄를 동반하는 담낭 종괴가 관찰되었으며 내시경 초음파에서 총담관까지 침범하는 담낭암이 의심되었다. 저자들은 ERCP를 통한 조직검사를 통해 진단한 담낭에 발생한 신경내분비암 1예를 경험하여 문헌 고찰과 함께 보고한다.

Keywords

References

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