Radiation Oncology Journal

The Korean Society for Radiation Oncology (대한방사선종양학회)
권호 표지
DOI QR코드

DOI QR Code

Variable uterine uptake of FDG in adenomyosis during concurrent chemoradiation therapy for cervical cancer

  • Yu, Jeong-Il (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Huh, Seung-Jae (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Young-Il (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Tae-Joong (Department of Obstetrics and Gynaecology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Park, Byung-Kwan (Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • Received : 2011.05.25
  • Accepted : 2011.06.10
  • Published : 2011.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

To avoid improper tumor volume contouring in radiation therapy (RT) and other invasive procedures, we report a case of uterine adenomyosis showing increased $^{18}F$-fluorodeoxyglucose (FDG) uptake on positron emission tomography (PET)/computed tomography (CT) mimicking malignant tumor in a 44-year-old woman during concurrent chemoradiation therapy (CCRT) for uterine cervical cancer. The adenomyosis was not associated with her menstrual cycle or with normal endometrium uptake, and it resolved one month after completion of RT. This case indicates that uterine adenomyosis in a premenopausal woman may show false positive uptake of $^{18}FDG$-PET/CT associated with CCRT.

Keywords

References

  1. Grigsby PW. The prognostic value of PET and PET/CT in cervical cancer. Cancer Imaging 2008;8:146-55. https://doi.org/10.1102/1470-7330.2008.0022
  2. Liu Y, Ghesani NV, Zuckier LS. Physiology and pathophysiology of incidental findings detected on FDG-PET scintigraphy. Semin Nucl Med 2010;40:294-315. https://doi.org/10.1053/j.semnuclmed.2010.02.002
  3. Exacoustos C, Brienza AL, Di Giovanni A, et al. Adenomyosis: three dimensional (3D) sonographic fi ndings of the junctional zone and correlation to histology. Ultrasound Obstet Gynecol 2011;37:471-9. https://doi.org/10.1002/uog.8900
  4. Graham KJ, Hulst FA, Vogelnest L, Fraser IS, Shilton CM. Uterine adenomyosis in an orang-utan (Pongo abelii/ pygmaeus). Aust Vet J 2009;87:66-9. https://doi.org/10.1111/j.1751-0813.2008.00370.x
  5. Fujiwara T, Togashi K, Yamaoka T, et al. Kinematics of the uterus: cine mode MR imaging. Radiographics 2004;24:e19. https://doi.org/10.1148/rg.e19
  6. Lerman H, Metser U, Grisaru D, Fishman A, Lievshitz G, Even-Sapir E. Normal and abnormal 18F-FDG endometrial and ovarian uptake in pre- and postmenopausal patients: assessment by PET/CT. J Nucl Med 2004;45:266-71.
  7. Kitajima K, Murakami K, Kaji Y, Sugimura K. Spectrum of FDG PET/CT findings of uterine tumors. AJR Am J Roentgenol 2010;195:737-43. https://doi.org/10.2214/AJR.09.4074
  8. Signorile PG, Baldi A. Endometriosis: new concepts in the pathogenesis. Int J Biochem Cell Biol 2010;42:778-80. https://doi.org/10.1016/j.biocel.2010.03.008

Cited by

  1. Primary Uterine Peripheral T-cell Lymphoma : A Case Report of MRI and 18 F-FDG PET/CT Findings vol.95, pp.17, 2011, https://doi.org/10.1097/md.0000000000003532
  2. PET/CT Variants and Pitfalls in Gynecological Cancers vol.51, pp.6, 2011, https://doi.org/10.1053/j.semnuclmed.2021.06.006