Treatment in Patients with Early-Stage Hodgkin's Lymphoma

국소형 호지킨 림프종의 치료

  • Lee, Sung-Eun (Department of Hematology, Seoul St. Mary’s Hospital, The Catholic University of Korea College of Medicine) ;
  • Cho, Seok-Goo (Department of Hematology, Seoul St. Mary’s Hospital, The Catholic University of Korea College of Medicine)
  • 이성은 (가톨릭대학교 의과대학 서울성모병원 혈액내과) ;
  • 조석구 (가톨릭대학교 의과대학 서울성모병원 혈액내과)
  • Published : 2011.11.01

Abstract

As there has been much progress in radiation therapy, and effective chemotherapy were introduced, the survival outcome of patients with Hodgkin's lymphoma has been significantly improved. Particularly, more than 90% of the patients with early-stage Hodgkin's lymphoma are expected to survive for at least 5 years. This very high survival rate and increasing recognition of the long-term toxicity of treatment including second malignancies led to current studies designed to reduce or eliminate the radiotherapy and minimize the number of chemotherapy cycles. However, because patients with early-stage Hodgkin's lymphoma are not homogeneous group recognition of risk factors in identification of unfavorable Hodgkin's lymphoma is essential for successful therapeutic strategy. Therefore, we will review risk assessment strategies with reference to publications and discuss current standard therapy to maximize therapeutic outcomes and to minimize late, potentially fatal toxicity in early-stage Hodgkin's lymphoma.

Keywords

References

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