The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지

Pathologic Characteristics and Differential Diagnosis of Hodgkin Lymphoma

호지킨 림프종의 병리학적 특징과 감별진단

  • Cha, Hee-Jeong (Department of Pathology, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Huh, Joo-Ryung (Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine)
  • 차희정 (울산대학교 의과대학 울산대학교병원) ;
  • 허주영 (울산대학교 의과대학 서울아산병원 병리과)
  • Published : 2011.11.01
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Abstract

Recent advances in the understanding of the biology of Hodgkin lymphoma have led to a new classification. Hodgkin lymphoma is now recognized as a B-cell disorder of germinal center or post-germinal center origin. In the WHO classification, Hodgkin lymphoma consists of two categories, namely, nodular lymphocyte predominant Hodgkin lymphoma and classical Hodgkin lymphoma. Classical Hodgkin lymphoma encompasses not only nodular sclerosis, mixed cellularity, and lymphocyte depletion subtypes, but also lymphocyte-rich subtype, among which, nodular sclerosis stands out as a distinct entity. A borderline neoplasm with features intermediate between Hodgkin lymphoma and diffuse large B-cell lymphoma has also been recognized.

Keywords

References

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