Feasibility of Stereotactic Biopsy for Breast Lesions with the Patient in the Decubitus Position: Our Early Experience

옆으로 누운 자세에서 유방병변의 입체정위 생검의 실행 가능성: 초기 경험

  • Lee, Tae-Kil (Department of Radiology, Yonsei University College of Medicine) ;
  • Kim, Min-Jung (Department of Radiology, Yonsei University College of Medicine) ;
  • Kim, Eun-Kyung (Department of Radiology, Yonsei University College of Medicine)
  • 이태길 (연세대학교세브란스병원영상의학과) ;
  • 김민정 (연세대학교세브란스병원영상의학과) ;
  • 김은경 (연세대학교세브란스병원영상의학과)
  • Published : 2011.01.01

Abstract

Purpose: We performed add-on type stereotactic vaccum-assisted breast biopsy (SVABB) with the patient in the decubitus position and we determined the feasibility of SVABB according to the breast thickness, the vicinity of the lesion in relation to the chest wall and the histopathologic diagnosis, and we report here on our initial experience. Materials and Methods: 81 patients with 82 lesions underwent SVABB. We measured the distance of the lesion from the chest wall on the basis of mammography, and we evaluated the breast thickness on the basis of the magnified, stereotactic view. The histopathologic results and the rate of underestimating atypical findings and ductal carcinoma in situ were analyzed. Results: The range of breast thickness was 12~61 mm on the magnified view and the range of breast thickness was 16~55 mm on the stereotactic view. The range of the distance of the lesion to the chest wall was 0~67 mm. The histopathologic results of SVABB demonstrated benign findings for 62 lesions, atypical findings for 10 lesions, ductal carcinoma in situ for 8 lesions and invasive ductal carcinoma for 2 lesions. The estimated underestimation rate was 30% (3/10) for the atypical finding and 0% (0/7) for ductal carcinoma in situ. Conclusion: This study demonstrated the results of add-on type SVABB with the patient in the decubitus position and SVABB was successful for patients with various lesion locations and breast thicknesses.

목적: 옆으로 누운 자세로 부착식 입체정위 흡입보조생검을 시행 시 환자의 유방 두께 및 흉벽과 병변의 거리에 따른 시술의 실현 가능성 및 석회화 적출빈도와 병리조직학적 결과의 초기 경험에 대해 알아보고자 하였다. 대상과 방법: 81명의 환자의 82개의 병변에서 입체정위 흡입보조생검을 시행하였다. 유방촬영술을 바탕으로 흉벽과 병변의 거리를 측정하였으며, 유방확대촬영술과 시술 시 유방 두께를 측정하였다. 병리조직학적 결과 및 비정형 관상피증식증, 상피내암의 저평가율을 평가하였다. 결과: 유방확대촬영술에서 유방두께는 12~61 mm였으며, 입체정위 생검 시 유방두께는 16~55 mm로 측정되었다. 흉벽과 병변의 거리는 0~67 mm에서 분포하였다. 병리 조직검사 결과는 62개(75.6%)의 병변에서 양성, 10개(12.1%)의 병변에서 비정형 관상피증식증, 8개 (9.7%)의 병변에서 상피내암, 그리고 2개(2.4%)에서는 침습성 관상피암으로 판정되었다. 비정형 관상피증식증의 저평가율은 30%(3/10)로 측정되었으며, 상피내암의 저평가율은 0.0% (0/7)로 측정되었다. 결론: 옆으로 누운자세로 시행한 부착식 입체정위 흡입 조직 생검에 대한 연구결과로서, 다양한 병변의 위치와 유방의 두께의 환자군에서 성공적인 조직생검이 가능하였다.

Keywords

References

  1. Parker SH, Lovin JD, Jobe WE, Luethke JM, Hopper KD, Yakes WF, et al. Stereotactic breast biopsy with a biopsy gun. Radiology 1990;176:741-747 https://doi.org/10.1148/radiology.176.3.2167501
  2. Lee CH, Egglin TK, Philpotts L, Mainiero MB, Tocino I. Cost-effectiveness of stereotactic core needle biopsy: analysis by means of mammographic findings. Radiology 1997;202:849-854 https://doi.org/10.1148/radiology.202.3.9051045
  3. Brenner RJ, Bassett LW, Fajardo LL, Dershaw DD, Evans WP 3rd, Hunt R, et al. Stereotactic core-needle breast biopsy: a multi-institutional prospective trial. Radiology 2001;218:866-872 https://doi.org/10.1148/radiology.218.3.r01mr44866
  4. Liberman L, Sama MP. Cost-effectiveness of stereotactic 11-gauge directional vacuum-assisted breast biopsy. AJR Am J Roentgenol 2000;175:53-58 https://doi.org/10.2214/ajr.175.1.1750053
  5. Kirshenbaum KJ, Voruganti T, Overbeeke C, Kirshenbaum MD, Patel P, Kaplan G, et al. Stereotactic core needle biopsy of nonpalpable breast lesions using a conventional mammography unit with an add-on device. AJR Am J Roentgenol 2003;181:527-531 https://doi.org/10.2214/ajr.181.2.1810527
  6. Han BK, Choe YH, Ko YH, Nam SJ, Kim JH, Yang JH. Stereotactic core-needle biopsy of non-mass calcifications: outcome and accuracy at long-term follow-up. Korean J Radiol 2003;4:217-223 https://doi.org/10.3348/kjr.2003.4.4.217
  7. Seo MR, Park JM, Gong GY, Ahn SH. Results with Add-on Stereotactic Core Biopsy (ASCB) of the Breast Lesions. J Korean Radiol Soc 2000:43:245-250 https://doi.org/10.3348/jkrs.2000.43.2.245
  8. American College of Radiology. Breast imaging reporting and data system (BI-RADS), 4th ed. Reston. VA.: America College of Radiology, 2003
  9. Liberman L, Feng TL, Dershaw DD, Morris EA, Abramson AF. US-guided core breast biopsy: use and cost-effectiveness. Radiology 1998;208:717-723 https://doi.org/10.1148/radiology.208.3.9722851
  10. Dillon MF, Hill AD, Quinn CM, O'Doherty A, McDermott EW, O'Higgins N. The accuracy of ultrasound, stereotactic, and clinical core biopsies in the diagnosis of breast cancer, with an analysis of false-negative cases. Ann Surg 2005;242:701-707 https://doi.org/10.1097/01.sla.0000186186.05971.e0
  11. Fajardo LL, Pisano ED, Caudry DJ, Gatsonis CA, Berg WA, Connolly J, et al. Stereotactic and sonographic large-core biopsy of nonpalpable breast lesions: results of the Radiologic Diagnostic Oncology Group V study. Acad Radiol 2004;11:293-308 https://doi.org/10.1016/S1076-6332(03)00510-5
  12. Caines JS, McPhee MD, Konok GP, Wright BA. Stereotaxic needle core biopsy of breast lesions using a regular mammographic table with an adaptable stereotaxic device. AJR Am J Roentgenol 1994;163:317-321 https://doi.org/10.2214/ajr.163.2.8037022
  13. Levin MF, Papoff WJ, Doan L, Eliasziw M. Stereotaxic percutaneous core biopsy versus surgical biopsy of nonpalpable breast lesions using a standard mammographic table with an add-on device. Can Assoc Radiol J 2001;52:29-32
  14. Becker L, Taves D, McCurdy L, Muscedere G, Karlik S, Ward S. Stereotactic core biopsy of breast microcalcifications: comparison of film versus digital mammography, both using an add-on unit. AJR Am J Roentgenol 2001;177:1451-1457 https://doi.org/10.2214/ajr.177.6.1771451
  15. Nakamura Y, Urashima M, Matsuura A, Nishihara R, Itoh A, Kagemoto M, et al. Stereotactic directional vacuum-assisted breast biopsy using lateral approach. Breast Cancer 2010;17:286-289 https://doi.org/10.1007/s12282-009-0162-4
  16. Liberman L, Smolkin JH, Dershaw DD, Morris EA, Abramson AF, Rosen PP. Calcification retrieval at stereotactic, 11-gauge, directional, vacuum-assisted breast biopsy. Radiology 1998;208:251-260 https://doi.org/10.1148/radiology.208.1.9646821
  17. Kim SH, Lee JH, Song BJ, Jung SS. Stereotactic vacuum-assisted biopsy of microcalcifications using an upright add-on type stereotactic mammography unit. J Korean Radiol Soc 2007;57:291-297 https://doi.org/10.3348/jkrs.2007.57.3.291
  18. Liberman L, Evans WP 3rd, Dershaw DD, Hann LE, Deutch BM, Abramson AF, et al. Radiography of microcalcifications in stereotaxic mammary core biopsy specimens. Radiology 1994;190:223-225 https://doi.org/10.1148/radiology.190.1.8259409
  19. Philpotts LE, Shaheen NA, Carter D, Lange RC, Lee CH. Comparison of rebiopsy rates after stereotactic core needle biopsy of the breast with 11-gauge vacuum suction probe versus 14-gauge needle and automatic gun. AJR Am J Roentgenol 1999;172:683-687 https://doi.org/10.2214/ajr.172.3.10063860
  20. Sohn V, Arthurs Z, Herbert G, Keylock J, Perry J, Eckert M, et al. Atypical ductal hyperplasia: improved accuracy with the 11-gauge vacuum-assisted versus the 14-gauge core biopsy needle. Ann Surg Oncol 2007;14:2497-2501 https://doi.org/10.1245/s10434-007-9454-0
  21. Pfarl G, Helbich TH, Riedl CC, Wagner T, Gnant M, Rudas M, et al. Stereotactic 11-gauge vacuum-assisted breast biopsy: a validation study. AJR Am J Roentgenol 2002;179:1503-1507 https://doi.org/10.2214/ajr.179.6.1791503
  22. Won B, Reynolds HE, Lazaridis CL, Jackson VP. Stereotactic biopsy of ductal carcinoma in situ of the breast using an 11-gauge vacuum- assisted device: persistent underestimation of disease. AJR Am J Roentgenol 1999;173:227-229 https://doi.org/10.2214/ajr.173.1.10397131
  23. Bagnall MJ, Evans AJ, Wilson AR, Burrell H, Pinder SE, Ellis IO. When have mammographic calcifications been adequately sampled at needle core biopsy? Clin Radiol 2000;55:548-553 https://doi.org/10.1053/crad.1999.0483
  24. Kettritz U, Rotter K, Schreer I, Murauer M, Schulz-Wendtland R, Peter D, et al. Stereotactic vacuum-assisted breast biopsy in 2874 patients: a multicenter study. Cancer 2004;100:245-251 https://doi.org/10.1002/cncr.11887