A Case of Synchronous Colorectal Adenocarcinoma with Anal Squamous Cell Carcinoma

동시에 발생한 대장의 선암과 항문의 편평상피세포암 1예

  • Jung, Bo-Yong (Department of Internal Medecine, Cheonan Hospital, Soonchunhyang University College of Medicine) ;
  • Lee, Suck-Ho (Department of Internal Medecine, Cheonan Hospital, Soonchunhyang University College of Medicine) ;
  • Lee, Chang-Kyun (Department of Internal Medecine, Cheonan Hospital, Soonchunhyang University College of Medicine) ;
  • Park, Eun-Seo (Department of Internal Medecine, Cheonan Hospital, Soonchunhyang University College of Medicine) ;
  • Chung, Il-Kwun (Department of Internal Medecine, Cheonan Hospital, Soonchunhyang University College of Medicine) ;
  • Kim, Sun-Joo (Department of Internal Medecine, Cheonan Hospital, Soonchunhyang University College of Medicine) ;
  • Baek, Moo-Jun (Department of Surgery Cheonan Hospital, Soonchunhyang University College of Medicine) ;
  • Lee, Ji-Hye (Department of Pathology, Cheonan Hospital, Soonchunhyang University College of Medicine)
  • 정보용 (순천향대학교 의과대학 천안병원 내과학교실) ;
  • 이석호 (순천향대학교 의과대학 천안병원 내과학교실) ;
  • 이창균 (순천향대학교 의과대학 천안병원 내과학교실) ;
  • 박은서 (순천향대학교 의과대학 천안병원 내과학교실) ;
  • 정일권 (순천향대학교 의과대학 천안병원 내과학교실) ;
  • 김선주 (순천향대학교 의과대학 천안병원 내과학교실) ;
  • 백무준 (순천향대학교 의과대학 천안병원 외과학교실) ;
  • 이지혜 (순천향대학교 의과대학 천안병원 병리학교실)
  • Published : 2011.01.30

Abstract

Synchronous anal squamous cell carcinoma with colorectal adenocarcinoma is a very rare and interesting disease entity because these neoplasms are essentially different from each other in terms of their anatomical locations, clinical behaviors, histopathological characteristics and treatment. To date, there have been very few case reports regarding the concurrent occurrence of these two distinct neoplasms. Nonetheless, it is recommended that patients with squamous cell carcinoma of the anus and who are older than 50 years should undergo colonoscopy in order to rule out a synchronous colorectal neoplasm. We recently encountered a 72-year-old woman who presented with synchronous squamous cell carcinoma of the anal canal and adenocarcinoma of the rectosigmoid junction. The patient underwent curative surgical resection for the colorectal adenocarcinoma and chemoradiotherapy for the concurrent anal squamous cell carcinoma. We describe here our clinical experience with this unusual case and we also conduct a short review of relevant literature.

대장암과 항문암은 소화기계암으로 비슷한 임상양상을 보일것 같지만, 원인, 증상, 암의 조직 형태, 치료 등에서 많은 차이를 보인다. 대장암이 대장의 다른 부위에서 동시성으로 발견되는 경우는 흔하지만, 대장암과 항문암이 동시성으로 발견된 증례는 거의 없었다. 하지만, 대장암과 항문암은 50세 이후의 연령에서 호발하므로 두 암이 동시성으로 발생할 가능성이 있기 때문에 항문암 환자는 대장암의 유무를 잘 확인해야 한다. 저자들은 고령의 여자환자가 혈변을 주소로 내원하여 대장암과 항문암을 동시에 진단받은 후 대장암의 복강경하 수술 절제 후 항문암에 화학-방사선 병합치료 중인 1예를 문헌고찰과 함께 보고한다.

Keywords

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