Endoscopic Resection of Early Gastric Cancer

조기위암의 내시경치료

  • Choi, Kee-Don (Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine)
  • 최기돈 (울산대학교 의과대학 서울아산병원 소화기내과)
  • Published : 2011.07.01

Abstract

Endoscopic resection has become accepted as a standard treatment in selected patients with early gastric cancer (EGC) with negligible risk of lymph node metastasis. Endoscopic resection preserves the stomach and therefore improves quality of life compared with surgery. And it allows accurate histological staging of the tumor, which is critical in deciding whether additional treatment is necessary. The endoscopic submucosal dissection (ESD) method has been widely used with higher en bloc resection and complete resection rates than conventional endoscopic mucosal resection (EMR) with acceptable complication rates. Long-term clinical outcomes of these techniques are promising in terms of disease-free and overall survival. Recently, the expanded indication of endoscopic resection for early gastric cancer has been proposed because of technical advances of ESD. Long-term outcome data of the expanded indication are needed for the clinical application of the expanded criteria of ESD.

Keywords

References

  1. 김재준. EMR/ESD의 역사 및 국내의 현황. In: 대한소화기 내시경학회 ESD연구회. 소화관종양 내시경치료술의 실제. 서울: 대한의학서적, 2009:28-39.
  2. Kim SG. Endoscopic resection of early gastric cancer. Korean J Gastroenterol 2009;54:77-82. https://doi.org/10.4166/kjg.2009.54.2.77
  3. Tada M, Murakami A, Karita M, Yanai H, Okita K. Endoscopic resection of early gastric cancer. Endoscopy 1993;25:445-450. https://doi.org/10.1055/s-2007-1010365
  4. Inoue H, Takeshita K, Hori H, Muraoka Y, Yoneshima H, Endo M. Endoscopic mucosal resection with a cap-fitted panendoscope for esophagus, stomach, and colon mucosal lesions. Gastrointest Endosc 1993;39:58-62. https://doi.org/10.1016/S0016-5107(93)70012-7
  5. Suzuki H. Endoscopic mucosal resection using ligating device for early gastric cancer. Gastrointest Endosc Clin N Am 2001;11:511-518.
  6. Kantsevoy SV, Adler DG, Conway JD, et al. Endoscopic mucosal resection and endoscopic submucosal dissection. Gastrointest Endosc 2008;68:11-18. https://doi.org/10.1016/j.gie.2008.01.037
  7. Miyata M, Yokoyama Y, Okoyama N, et al. What are the appropriate indications for endoscopic mucosal resection for early gastric cancer? Analysis of 256 endoscopically resected lesions. Endoscopy 2000;32:773-778. https://doi.org/10.1055/s-2000-7712
  8. Noda M, Kodama T, Atsumi M, et al. Possibilities and limitations of endoscopic resection for early gastric cancer. Endoscopy 1997;29:361-365. https://doi.org/10.1055/s-2007-1004216
  9. Ono H. Early gastric cancer: diagnosis, pathology, treatment techniques and treatment outcomes. Eur J Gastroenterol Hepatol 2006;18:863-866. https://doi.org/10.1097/00042737-200608000-00009
  10. Park JC, Lee SK, Seo JH, et al. Predictive factors for local recurrence after endoscopic resection for early gastric cancer: long-term clinical outcome in a single-center experience. Surg Endosc 2010;24:2842-2849. https://doi.org/10.1007/s00464-010-1060-8
  11. Ahn JY, Choi KD, Choi JY, et al. Procedure time of endoscopic submucosal dissection according to the size and location of early gastric cancers: analysis of 916 dissections performed by 4 experts. Gastrointest Endosc 2011;73:911-916. https://doi.org/10.1016/j.gie.2010.11.046
  12. Gotoda T, Yanagisawa A, Sasako M, et al. Incidence of lymph node metastasis from early gastric cancer: estimation with a large number of cases at two large centers. Gastric Cancer 2000;3:219-225. https://doi.org/10.1007/PL00011720
  13. Chung JW, Jung HY, Choi KD, et al. Extended indication of endoscopic resection for mucosal early gastric cancer: analysis of a single center experience. J Gastroenterol Hepatol 2011;26:884-887, doi: 10.1111/j.1440-1746.2010.06611.x.
  14. Jee YS, Hwang SH, Rao J, et al. Safety of extended endoscopic mucosal resection and endoscopic submucosal dissection following the Japanese Gastric Cancer Association Treatment Guidelines. Br J Surg 2009;96:1157-1161. https://doi.org/10.1002/bjs.6686
  15. Ha TK, An JY, Youn HK, Noh JH, Sohn TS, Kim S. Indication for endoscopic mucosal resection in early signet ring cell gastric cancer. Ann Surg Oncol 2008;15:508-513. https://doi.org/10.1245/s10434-007-9660-9
  16. Kim JH, Lee YC, Kim H, et al. Endoscopic resection for undifferentiated early gastric cancer. Gastrointest Endosc 2009;69:e1-e9. https://doi.org/10.1016/j.gie.2008.10.040
  17. Kang HY, Kim SG, Kim JS, Jung HC, Song IS. Clinical outcomes of endoscopic submucosal dissection for undifferentiated early gastric cancer. Surg Endosc 2010;24:509-516. https://doi.org/10.1007/s00464-009-0614-0
  18. Seo JH, Park JC, Kim YJ, Shin SK, Lee YC, Lee SK. Undifferentiated histology after endoscopic resection may predict synchronous and metachronous occurrence of early gastric cancer. Digestion 2010;81:35-42. https://doi.org/10.1159/000235921
  19. Hirasawa T, Fujisaki J, Fukunaga T, et al. Lymph node metastasis from undifferentiated-type mucosal gastric cancer satisfying the expanded criteria for endoscopic resection based on routine histological examination. Gastric Cancer 2010;13:267-270. https://doi.org/10.1007/s10120-010-0577-9
  20. Kim GH, Park do Y, Kida M, et al. Accuracy of high-frequency catheter-based endoscopic ultrasonography according to the indications for endoscopic treatment of early gastric cancer. J Gastroenterol Hepatol 2010;25:506-511. https://doi.org/10.1111/j.1440-1746.2009.06111.x
  21. Kida M. EUS in gastric cancer. In: Hawes RH, Fockens P, eds. Endosonography. Philadelphia: Saunders Elsevier, 2006:111-126.
  22. Kwee RM, Kwee TC. The accuracy of endoscopic ultrasonography in differentiating mucosal from deeper gastric cancer. Am J Gastroenterol 2008;103:1801-1809. https://doi.org/10.1111/j.1572-0241.2008.01923.x
  23. Okada K, Fujisaki J, Kasuga A, et al. Endoscopic ultrasonography is valuable for identifying early gastric cancers meeting expanded-indication criteria for endoscopic submucosal dissection. Surg Endosc 2011;25:841-848. https://doi.org/10.1007/s00464-010-1279-4
  24. Choi J, Kim SG, Im JP, Kim JS, Jung HC, Song IS. Comparison of endoscopic ultrasonography and conventional endoscopy for prediction of depth of tumor invasion in early gastric cancer. Endoscopy 2010;42:705-713. https://doi.org/10.1055/s-0030-1255617
  25. Choi J, Kim SG, Im JP, Kim JS, Jung HC, Song IS. Endoscopic prediction of tumor invasion depth in early gastric cancer. Gastrointest Endosc 2011;73:917-927. https://doi.org/10.1016/j.gie.2010.11.053
  26. Gotoda T, Yamamoto H, Soetikno RM. Endoscopic submucosal dissection of early gastric cancer. J Gastroenterol 2006;41:929-942. https://doi.org/10.1007/s00535-006-1954-3
  27. Soetikno R, Kaltenbach T, Yeh R, Gotoda T. Endoscopic mucosal resection for early cancers of the upper gastrointestinal tract. J Clin Oncol 2005;23:4490-4498. https://doi.org/10.1200/JCO.2005.19.935
  28. Larghi A, Waxman I. State of the art on endoscopic mucosal resection and endoscopic submucosal dissection. Gastrointest Endosc Clin N Am 2007;17:441-469. https://doi.org/10.1016/j.giec.2007.05.012
  29. Gotoda T. Endoscopic resection of early gastric cancer: the Japanese perspective. Curr Opin Gastroenterol 2006;22:561-569. https://doi.org/10.1097/01.mog.0000239873.06243.00
  30. Jeon SW, Jung MK, Kim SK, et al. Clinical outcomes for perforations during endoscopic submucosal dissection in patients with gastric lesions. Surg Endosc 2010;24:911-916. https://doi.org/10.1007/s00464-009-0693-y
  31. Kojima T, Parra-Blanco A, Takahashi H, Fujita R. Outcome of endoscopic mucosal resection for early gastric cancer: review of the Japanese literature. Gastrointest Endosc 1998;48:550-554;discussion 554-555. https://doi.org/10.1016/S0016-5107(98)70108-7
  32. Ono H, Kondo H, Gotoda T, et al. Endoscopic mucosal resection for treatment of early gastric cancer. Gut 2001;48:225-229. https://doi.org/10.1136/gut.48.2.225
  33. Choi KS, Jung HY, Choi KD, et al. EMR versus gastrectomy for intramucosal gastric cancer: comparison of long-term outcomes. Gastrointest Endosc 2011;73:942-948. https://doi.org/10.1016/j.gie.2010.12.032
  34. Isomoto H, Shikuwa S, Yamaguchi N, et al. Endoscopic submucosal dissection for early gastric cancer: a large-scale feasibility study. Gut 2009;58:331-336. https://doi.org/10.1136/gut.2008.165381