The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Late Adverse Reaction to Iodixanol ($Visipaque^{(R)}$)

$Visipaque^{(R)}$ 조영제 사용 후 발생한 후기 부작용 1예

  • Kim, Cha-Young (Department of Internal Medicine, Gyeongsang National University Hospital) ;
  • Kim, Hee-Jin (Department of Internal Medicine, Gyeongsang National University Hospital) ;
  • Kim, Moon-Jin (Department of Internal Medicine, Gyeongsang National University Hospital) ;
  • Kang, Yeo-Jin (Department of Internal Medicine, Gyeongsang National University Hospital) ;
  • Kim, Hyun-Jung (Department of Internal Medicine, Gyeongsang National University Hospital) ;
  • Chang, Se-Ho (Department of Internal Medicine, Gyeongsang National University Hospital) ;
  • Park, Dong-Jun (Department of Internal Medicine, Gyeongsang National University Hospital)
  • Published : 2011.07.01
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Abstract

Late adverse reactions to iodinated contrast medium are defined as reactions occurring 1 hour to 1 week after contrast medium injection. The majority of late adverse reactions are cutaneous reactions, and include itching, maculopapular rash, urticaria, erythematous patches, and angioedema. We report a patient with an iodixanol ($Visipaque^{(R)}$)-induced late adverse reaction. She was admitted for evaluation of nephrotic range proteinuria and edema. Abdomen and chest enhanced computed tomography was performed as a malignancy work-up. Sixteen hours after radiocontrast exposure, her entire body felt itchy. A maculopapular rash was first detected on her back and abdomen 24 hours after exposure, and spread over her entire body, including her face. Her skin lesions resolved completely in 5 days after administering steroid and antihistamine. We should consider late adverse reactions of iodinated contrast medium when we detect skin lesions late after radiocontrast use.

저자들은 신 증후군 환자에서 $Visipaque^{(R)}$ 사용 후 발생한 후기 지연 부작용을 경험하였고, 이를 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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