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Analysis of Benzo[a]pyrene Content and Risk Assessment

훈제식육식품 중 벤조피렌 함량 분석 및 안전성 평가

  • Cho, Hyoun-Kyoung (Department of Food Science and Biotechnology and Institute of Lotus Functional Foods Ingredients, Dongguk University) ;
  • Kim, Mee-Hye (Food Contaminants Division, National Institute of Food and Drug Safety Evaluation) ;
  • Park, Sung-Kug (Food Contaminants Division, National Institute of Food and Drug Safety Evaluation) ;
  • Shin, Han-Seung (Department of Food Science and Biotechnology and Institute of Lotus Functional Foods Ingredients, Dongguk University)
  • 조현경 (동국대학교 식품생명공학과 및 Lotus기능성식품소재연구소) ;
  • 김미혜 (식품의약품안전평가원 오염물질과) ;
  • 박성국 (식품의약품안전평가원 오염물질과) ;
  • 신한승 (동국대학교 식품생명공학과 및 Lotus기능성식품소재연구소)
  • Received : 2011.11.13
  • Accepted : 2011.12.13
  • Published : 2011.12.31

Abstract

The content of benzo[a]pyrene from 69 smoked meat products commonly consumed in Korean food market was analysed with high performance liquid chromatography. Smoked meat products including smoked chicken, pork, turkey and duck were saponified, extracted and cleaned up to analyze the benzo[a]pyrene content. As a result of analysis from smoked meat products, the mean benzo[a]pyrene content was 0.42 ${\mu}g$/kg and the highest content of benzo[a]pyrene was 2.87 ${\mu}g$/kg detected in smoked chicken product. All somked meat products contained benzo[a]pyrene below the limit regulated by Korean Food and Drug Administration (KFDA). Exposure assessment of benzo[a]pyrene from smoked meat products ingestion was calculated by using National Health and Nutrition Survey (NHNS). The estimated lifetime average daily intake of benzo[a]pyrene was 0.187 ng/kg bw/d. Margin of exposure of benzo[a]pyrene was ranged from 1,657,754 to 3,957,219.

훈제식육식품을 통한 polycyclic aromatic hydrocarbons(PAHs)의 대표독성물질인 benzo[a]pyrene의 위해도를 판단하기위해 시중에 유통되는 69개의 훈제식육식품을 통한 위해성을 평가하였다. 사용된 훈제식육식품은 훈제 치킨, 오리, 칠면조, 돼지 등이며 benzo[a]pyrene의 검출범위는 불검출-2.87 ${\mu}g$/kg이었고 평균 농도는 0.42 ${\mu}g$/kg로 나타났다. 2005 국민건강영양조사를 참고하여 만성1일인체노출량을 평가한 결과 훈제식육식품을 통한 노출량은 총 0.187 ng/kg B.W./d로 나타났다. 위해도 산출을 위하여 benzo[a]pyrene의 위상부암에 대한 BMDL값인 0.31-0.74 mg/kg B.W./d와 만성1일인체노출량을 이용하여 MOE를 구한결과 MOE는 1,657,754-3,957,219 수준으로 나타났다. Benzo[a]pyrene의 오염도는 식품의약품안전청에서 제시하는 기준규격인 5 ${\mu}g$/kg 이하로 나타나 훈제식육식품을 통한 benzo[a]pyrene의 노출정도는 안전한것으로 판단된다.

Keywords

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