DOI QR코드

DOI QR Code

20~30대 성인 남성에서 체질량지수, 흡연량 및 음주량과 혈액검사치의 관련성

The Relation of BMI, Smoking and Drinking with Biomedical Parameters in 20s and 30s Men

  • 투고 : 2011.08.18
  • 심사 : 2011.10.06
  • 발행 : 2011.10.31

초록

본 연구는 20~30대 초기 성인기 남성에서 체질량지수, 흡연량 및 음주량과 혈액검사치의 관련성을 알아보기 위하여 탐색적 후향 연구로 시도되었다. 연구대상자는 서울시내 일개 상급종합병원에서 2006년 10월부터 2011년 6월까지 임상시험 참여를 위해 일반건강검진을 받은 20~30대 남성 총 603명이었다. 연구결과 비만 그룹은 정상체중 그룹에 비해 적혈구수, 혈색소, 적혈구용적률, 중성지방, 요산, ALT가 유의하게 높았다. 흡연자는 비흡연자에 비해 백혈구수와 혈색소는 유의하게 높고 단백질은 유의하게 낮았으며, 10~19개비 흡연하는 사람은 비흡연자 및 10개비 미만 흡연자에 비해 혈소판은 유의하게 높고 알부민은 유의하게 낮았으며, 10~19개비 흡연하는 사람은 비흡연자에 비해 중성지방은 유의하게 높고 혈당은 유의하게 낮았다. 일일 10g 이상 음주자는 10g 미만 음주자 및 비음주자에 비해 AST와 ALT가 유의하게 높았다. 체질량지수는 적혈구수, 혈색소, 적혈구용적률, 총콜레스테롤, 중성지방, 혈당, 요산, AST, ALT 증가에 유의하게 영향을 미쳤으며, 흡연량은 백혈구수치, 혈색소, 적혈구용적률, 중성지방 증가에 유의하게 영향을 미쳤고, 혈당과 칼슘의 감소에 유의한 영향을 미쳤다. 음주량은 총콜레스테롤, AST, ALT 증가에 유의한 영향 요인이었으며, 백혈구수치 감소에 유의한 영향요인이었다. 결론적으로 20~30대 성인 남성의 혈색소, 총 콜레스테롤, 중성지방, ALT 등의 혈액검사결과와 체질량지수, 흡연 및 음주 간에 유의한 관련이 있으므로 생활습관성 질환을 예방하기 위하여 초기 성인기부터 비만 예방, 금연 및 과음을 방지하는 건강생활 실천 활동을 수행해야 할 것으로 보인다.

The purpose of this study was to explore the relation of BMI, smoking and drinking with biomedical parameters in 20s and 30s men. This was a retrospective exploratory study and the subjects were 603 men who participated in health check-up for clinical trial at a tertiary hospital between October 2006 and June 2011. RBC, hemoglobin(Hb), hematocrit(Hct), triglyceride(TG), uric acid(UA), ALT in obese group were significantly higher than those of normal weight group. WBC and Hb in smokers were significantly higher than those of nonsmokers, protein in smokers was significantly lower than that of nonsmokers. Platelet in moderate smokers who smoke 10~19 cigarettes a day was significantly higher than that of nonsmokers and light smokers who smoke below 10 cigarettes a day, albumin in moderate smokers was significantly lower than that of nonsmokers and light smokers. TG in moderate smokers was significantly higher than that of nonsmokers, and blood glucose(BG) in moderate smokers was significantly lower than that of nonsmokers. AST and ALT in drinkers who drink over 10g a day were significantly higher than those of nondrinkers. In regression, BMI was significant factors of increasing RBC, Hb, Hct, total cholesterol(TC), TG, BG, UA, AST and ALT. Smoking amount was significant factors of increasing WBC, Hb, Hct and TG, and was significant factors of decreasing BG and Ca. Smoking amount was significant factors of increasing TC, AST and ALT, and was significant factors of decreasing WBC. In conclusion, there was significant relations of BMI, smoking, and drinking with biomedical parameters such as Hb, TC, TG, and ALT in young-aged men. Therefore, practice of healthy lifestyle activities to include preventing obesity and heavy drinking, and quitting smoking needs to the 20s and 30s men for preventing lifestyle disease.

키워드

참고문헌

  1. Ministry of Health & Welfare, National Health Plan 2011-2020, Ministry of Health & Welfare, 2011.
  2. Ministry of Health & Welfare, 2009 National Health Statistics, Ministry of Health & Welfare, 2010.
  3. I. S. Kim, "Health Promotion", Journal of nursing query, Vol.2, No.2, pp. 12-20, 1993.
  4. Y. Chun, N. Kim, "Study on Health Care For Korean Adults", The Research Institute of Sports Science, Vol.17, pp. 1-24, 2002. https://doi.org/10.1016/S0765-1597(01)00116-2
  5. The National Health Insurance Corporation, 2011 medical checkup information, The National Health Insurance Corporation, 2011.
  6. C. Yoo, et al., "Properties of Blood Pressure and Routine Laboratory Test Results by the Status of Smoking and Alcohol Intakes in Male Workers", Journal of Korean Society for Health Education and Promotion, Vol.20, No.1, pp. 131-145, 2003.
  7. K. Park, Y. Cho, "The Abnormal Rates of Blood Pressures and Blood Biochemical Properties with BMI in Health Checkup Examinees", Journal of the Korea Academia-Industrial cooperation Society, Vol.11, No.12, pp. 4843-4853, 2010. https://doi.org/10.5762/KAIS.2010.11.12.4843
  8. M. Chan-Yeung, et al., "The effects of age, smoking, and alcohol on routine laboratory tests", Am J Clin Pathol, Vol.75, No.3, pp. 320-326, 1981. https://doi.org/10.1093/ajcp/75.3.320
  9. Y. Paik, K. Choi, "A study on the effect of smoking, alcohol intake and obesity on the serum levels of lipid and uric acid in male adult", The Ulsan University Medical Journal, Vol.4, No.1, pp. 71-78, 1995.
  10. S. W. Oh, "Effects of Alcohol on Obesity and Metabolic Syndrome", The Korean Journal of Obesity, Vol.18, No.1, pp. 1-7, 2009.
  11. E. B. Rimm, et al., "Moderate alcohol intake and lower risk of coronary heart disease: meta-analysis of effects on lipids and haemostatic factors", BMJ, Vol.11, No.319, pp. 1523-1528, 1999.
  12. G.I. Cho, et al., "A study on Relationship Between Health Behaviors and Some Related Factors of Healthy Adults", Inje Medical Journal, Vol.17, No.2, pp. 235-250, 1996.
  13. P. W. Liu, et al., "Serum uric acid and metabolic syndrome in Taiwanese adults", Metabolism, Vol.59, No.6, pp. 802-807, 2010. https://doi.org/10.1016/j.metabol.2009.09.027
  14. G. R. Kim, H. S. Yoon, "An Analysis of the Correlation between Health-related Habits and the Biochemical Characteristics of the Blood of Bus Drivers in the Masan Area", Journal of Community Nutrition, Vol.7, No.2, pp. 232-244, 2002.
  15. W. Y. Craig, et al., "Cigarette smoking and serum lipid and lipoprotein concentrations: an analysis of published data", British Medical Journal, Vol.298, No.6676, pp. 784-788, 1989. https://doi.org/10.1136/bmj.298.6676.784
  16. T. P. Whitehead, et al., "The effects of cigarette smoking and alcohol consumption on blood haemoglobin, erythrocytes and leucocytes: a dose related study on male subjects", Clin Lab Haematol, Vol.17, No.2, pp.131-138, 1995.
  17. S. H. Yun, et al., "Difference in hemoglobin between smokers and non-smokers", Korean J Fam Med, Vol.23, No.1, pp. 80-86, 2002.
  18. J. Jung, et al., "Associations between blood lipids and blood composition and inflammatory markers in obese female college students", Korean J Health Promot, Vol.10, No.1, pp. 10-15, 2010.
  19. Y. S. Suh, "The Effect of cigarette smoking on serum lipid profile", Korean J Fam Med, Vol.19, No.4, pp.383-393, 1998.
  20. K. Yamamoto, et al., "The relationship between psychosocial stress, age, BMI, CRP, lifestyle, and the metabolic syndrome in apparently healthy subjects", J Physiol Anthropol, Vol.30, No.1, pp. 15-22, 2011 https://doi.org/10.2114/jpa2.30.15
  21. e-National indicators. http://www.index.go.kr/egams/stYts/jsp/potal/ stts/PO_STTS_IdxMai n.jsp?i d x_cd=2771&bbs=INDX_001
  22. J. J. Cho, et al., "Effects of changes in lifestyle and biological parameters on blood lipid levels in middle agd men", Korean J Fam Med, Vol.21, No.6, pp. 782-791, 2000.
  23. B. H. Jin, J. Y. Kim, "Association Between Serum Total Cholesterol, Blood Pressure, Obesity and Life Style in a Population", The Korean public health association, Vol.21, No.2, pp. 3-18, 1995.
  24. K. J. Mukamal, et al., "Roles of drinking pattern and type of alcohol consumed in coronary heart disease in men", N Engl J Med, Vol.9, No.348(2), pp. 109-118, 2003.
  25. The Korean Society for the Study of Obesity, The Guideline of Obesity treatment 2009, Cheongwoon Printing, 2009.
  26. Asan Medical Center. Department of Laboratory Medicine: Guideline of Laboratory test, Asan Medical Center, 2006.
  27. K. Yamamoto, et al., "The relationship between IMPS-measured stress score and biomedical par ameters regarding health status among public school workers", J Physiol Anthropol. Vol.26, No.2, pp. 149-58, 2007. https://doi.org/10.2114/jpa2.26.149
  28. S. P. Park, et al., "Changes of Hematologic Parameters Associated With Life Style in Industrial Male Workers", The Korean public health association, Vol.28, No.1, pp. 39-51, 2002.
  29. Y. C. Cho, I. S. Song, "Characteristics of BMI , Blood Pressure and Serum Lipid Levels According to Age and Health Behavior in Industrial Workers", The Korean public health association, Vol.26, No.2, pp. 143-151, 2000.
  30. S. Rossner, "Obesity: the disease of the twenty-first century", Int J Obes Relat Metab Disord, Vol.26, Suppl 4, pp. S2-4, 2002. https://doi.org/10.1038/sj.ijo.0802209
  31. F. B. Hu, et al., "Diet, lifestyle, and the risk of type 2 diabetes mellitus in women", N Engl J Med, Vol.13, No.345(11), pp. 790-797, 2001.
  32. J. Dallongeville, et. al., "Cigarette smoking is associated with differences in nutritional habits and related to lipoprotein alterations independently of food and alcohol intake", Eur J Clin Nutr, Vol.50, No.10, pp. 647-654, 1996.
  33. E.J. Mayer, et al., "Alcohol consumption and insulin concentrations. Role of insulin in associations of alcohol intake with high-density lipoprotein cholesterol and triglycerides", Circulation, Vol.88, No.5, pp. 2190-2197, 1993. https://doi.org/10.1161/01.CIR.88.5.2190
  34. Y. Ruixing, et al., "Hyperlipidaemia and its risk fact ors in the Guangxi Bai Ku Yao and Han populations", Public Health Nutr, Vol.12, No.6, pp. 816-24, 2009. https://doi.org/10.1017/S1368980008003273

피인용 문헌

  1. Prevalence and Management of Dyslipidemia Among Korean Adults: KNHANES 2010-2012 vol.16, pp.11, 2015, https://doi.org/10.5762/KAIS.2015.16.11.7978
  2. Associations between Smoking, Drinking and Depression among Korean Adults: The 5th Korea National Health and Nutrition Examination Survey vol.16, pp.2, 2016, https://doi.org/10.15384/kjhp.2016.16.2.111