Journal of the Optical Society of Korea

  • 제15권4호
  • /
  • Pages.321-328
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  • 2011
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  • 1226-4776(pISSN)
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  • 2093-6885(eISSN)
한국광학회 (Optical Society of Korea)
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Numerical Modeling of Compression-Controlled Low-level Laser Probe for Increasing Photon Density in Soft Tissue

  • Kwon, Ki-Woon (Department of Mathematics, Dongguk University) ;
  • Son, Tae-Yoon (Department of Biomedical Engineering, Yonsei University) ;
  • Yeo, Chang-Min (Department of Biomedical Engineering, Yonsei University) ;
  • Jung, Byung-Jo (Department of Biomedical Engineering, Yonsei University)
  • 투고 : 2011.07.19
  • 심사 : 2011.10.17
  • 발행 : 2011.12.25
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초록

Various methods have been investigated to increase photon density in soft tissue, an important factor in low-level laser therapy. Previously we developed a compression-controlled low-level laser probe (CCLLP) utilizing mechanical negative compression, and experimentally verified its efficacy. In this study, we used Bezier curves to numerically simulate the skin deformation and photon density variation generated by the CCLLP. In addition, we numerically modeled changes in optical coefficients due to skin deformation using a linearization technique with appropriate parameterization. The simulated results were consistent with both human in vivo and porcine ex vivo experimental results, confirming the efficacy of the CCLLP.

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참고문헌

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피인용 문헌

  1. Polarization Properties of Quasi-Homogeneous Beams Propagating in Oceanic Turbulence vol.17, pp.2, 2013, https://doi.org/10.3807/JOSK.2013.17.2.130
  2. Mechanical compression in cross-polarization OCT imaging of skin: In vivo study and Monte Carlo simulation vol.3, pp.4, 2014, https://doi.org/10.1515/plm-2014-0015
  3. A new design of light illumination scheme for deep tissue photoacoustic imaging vol.20, pp.20, 2012, https://doi.org/10.1364/OE.20.022649