Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Synthesis, Structure, and Peroxidase Activity of an Octahedral Ru(III) Complex with a Tripodal Tetraamine Ligand

  • Cho, Jang-Hoon (Department of Chemistry and Green-Nano Materials Research Center, Kyungpook National University) ;
  • Kim, Kwan-Mook (Department of Chemistry and Nano Sciences, Ewha Womans University) ;
  • Noh, Dong-Youn (Department of Chemistry, Seoul Women's University) ;
  • Lee, Hong-In (Department of Chemistry and Green-Nano Materials Research Center, Kyungpook National University)
  • Received : 2011.07.25
  • Accepted : 2011.09.06
  • Published : 2011.11.20
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Abstract

A new octahedral Ru(III) complex with a tripodal tetraamine ligand, tpea = tris[2-(1-pyrazoyl)ethyl]amine, has been prepared and characterized. The single crystal X-ray crystallographic study of the complex revealed that the complex has a near octahedral geometry with the tetradentate ligand and two chloride ions. Peroxidase activity was examined by observing the oxidation of 2,2'-azinobis(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS) with hydrogen peroxide in the presence of the complex. Amount of $ABTS^{+{\bullet}}$ generated during the reaction was monitored by UV/VIS and EPR spectroscopies. After the initiation of the peroxidase reaction, $ABTS^{+{\bullet}}$ concentration increases and then decreases after certain time, indicating that both ABTS and $ABTS^{+{\bullet}}$ are the substrates of the peroxidase activity of the Ru(III) complex.

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