Toxicological Research

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
권호 표지
DOI QR코드

DOI QR Code

The Comparative Evaluation of Fermented and Non-fermented Soybean Extract on Antioxidation and Whitening

  • Chae, Ga-Yeon (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University) ;
  • Ha, Bae-Jin (Department of Pharmaceutical Engineering, College of Medical Life Science, Silla University)
  • Received : 2011.08.22
  • Accepted : 2011.11.06
  • Published : 2011.12.01
Download PDF
⟨ Previous Next ⟩

Abstract

The present study was performed to compare the antioxidative and whitening activities of fermented soybean extract (FSB) and non-fermented soybean extract (SB). Antioxidative and whitening activities of FSB and SB were evaluated by the determination of DPPH, superoxide radical and hydroxyl radical scavenging activities, linoleic acid inhibition activity, and tyrosinase inhibition activity. FSB showed the higher effect than SB in the antioxidative activities. Also FSB showed the better effect than SB in whitening activity. These results demonstrated that the fermentation played a more excellent role than the non-fermentation in antioxidation and whitening. Therefore, this study suggested that FSB could be a useful cosmetic ingredient for antioxidation and skin whitening.

Keywords

References

  1. Brichard, V., Van Pel, A., Wolfel, T., Wolfel, C., De Plaen, E., Lethe, B., Coulie, P. and Boon, T. (1993). The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J. Exp. Med., 178, 489-495. https://doi.org/10.1084/jem.178.2.489
  2. Cho, S.H., Park, B.Y., Kim, J.H., Kim, Y.K., Lee, J.M. and Ahn, C.N. (2006) Effect of r-oryzanol on lipid oxidation of linoleic acids and ground pork. J. Anim. Sci & Technol. Kor., 48, 587-594. https://doi.org/10.5187/JAST.2006.48.4.587
  3. Choi, J.N., Kim, J., Lee, M.Y., Park, D.K., Hong, Y.S. and Lee, C.H. (2010). Metabolomics Revealed Novel Isoflavones and Optimal Cultivation Time of Cordyceps militaris Fermentation. J. Agric. Food Chem., 58, 4258-4267. https://doi.org/10.1021/jf903822e
  4. Choi, G.H., Lee, J.H., Jo, M.N., Yoon, Y.C. and Paik, H.D. (2008). Growth and antioxidant production of Bacillus polyfermenticus SCD in whey protein concentrate (WPC)-based medium. Korean J. Food Sci. Anl. Resour., 28, 105-108. https://doi.org/10.5851/kosfa.2008.28.1.105
  5. Ebanks, J.P., Wickett, R.R. and Boissy, R.E. (2009). Mechanisms Regulating Skin Pigmentation: The Rise and Fall of Complexion Coloration. Int. J. Mol. Sci., 10, 4066-4087. https://doi.org/10.3390/ijms10094066
  6. Frias, J., Miranda, M.L., Doblado, R. and Vidal-Valverde, C. (2005). Effect of germination and fermentation on the antioxidant vitamin content and antioxidant capacity of Lupinus albus L. var. Multolupa. J. Food Chem., 92, 211-220. https://doi.org/10.1016/j.foodchem.2004.06.049
  7. Goupy, P., Vulcain, E., Caris-Veyrat, C. and Dangles, O. (2007). Dietary antioxidants as inhibitors of the heme-induced peroxidation of linoleic acid: Mechanism of action and synergism. Free Radic. Biol. Med., 43, 933-946. https://doi.org/10.1016/j.freeradbiomed.2007.06.013
  8. Gulcin, I. (2006). Antioxidant and antiradical activities of L-carnitine. Life Sci., 78, 803-811. https://doi.org/10.1016/j.lfs.2005.05.103
  9. Hayes, R.E., Bookwalter, G.N. and Bagley, E.B. (1977). Antioxidant activity of soybean flour and derivatives-A review. J. Food Sci., 42, 1527-1531 https://doi.org/10.1111/j.1365-2621.1977.tb08417.x
  10. Heo, S.I. and Wang, M.H. (2008). Antioxidant activity and cytotoxicity effect of extracts from Taraxacum mongolicum H. Kor. J. Pharmacogn., 39, 255-259.
  11. Kang, H.S., Chung, H.Y., Son, K.H., Kang, S.S. and Choi, J.S. (1959). Scavenging effect of korean medicinal plants on the peroxynitrite and total ROS. Natural Product Sciences, 9, 73-79.
  12. Kim, J.E., Kim, A.R. and Park, S.N. (2011). Antibacterial, antioxidative and antiaging effects of Allium cepa eel extracts. Appl. Chem. Eng., 22, 178-184.
  13. Kim, S.Y., Kim, C.R., Kim, H.M., Kong, M., Lee, J.H., Lee, H.J., Lim, M.S., Jo, N.R. and Park, S.N. (2010). Antioxidant activity and whitening effect of Cedrela sinensis A. Juss Shoots Extracts. J. Soc. Cosmet. Scientists Korea, 36, 175-182.
  14. Kuppusamy, P. and Zweier, J.L. (1989). Characterization of free radical generation by xanthine oxidase. J. Biol. Chem., 264, 9880-9884.
  15. Lee, Y.L., Yang, J.H. and Mau, J.L. (2008). Antioxidant properties of water extracts from Monascus fermented soybeans. Food Chem., 106, 1128-1137. https://doi.org/10.1016/j.foodchem.2007.07.047
  16. Lin, C.H., Wei, Y.T. and Chou, C.C. (2006). Enhanced antioxidative activity of soybean koji prepared with various filamentous fungi. Food Microbiol., 23, 628-633. https://doi.org/10.1016/j.fm.2005.12.004
  17. Makrantonaki, E. and Zouboulis, C.C. (2008). Skin alterations and diseases in advanced age. Drug Discov. Today, 5, 153-162. https://doi.org/10.1016/j.ddmec.2008.05.008
  18. Masaki, H., Sakaki, S., Atsumi, T. and Sakurai, H. (1995). Activeoxygen scavenging activity of plant extracts. Biol. Pharm. Bull., 18, 162-166. https://doi.org/10.1248/bpb.18.162
  19. Miyachi, Y. (1995). Photoaging from an oxidative standpoint. J. Dermatol. Sci., 9, 79-86. https://doi.org/10.1016/0923-1811(94)00363-J
  20. Nerya, O., Musa, R., Khatib, S., Tamir, S. and Vaya, J. (2004). Chalcones as potent tyrosinase inhibitors: the effect of hydroxyl positions and numbers. Phytochemistry, 65, 1389-1395. https://doi.org/10.1016/j.phytochem.2004.04.016
  21. Oender, K., Trost, A., Lanschuetzer, C., Laimer, M., Emberger, M., Breitenbach, M., Richter, K., Hintner, H. and Bauer, J.W. (2008). Cytokeratin-related loss of cellular integrity is not a major driving force of human intrinsic skin aging. Mech. Ageing Dev., 129, 563-571. https://doi.org/10.1016/j.mad.2008.05.008
  22. Park, S.J. (2009). Biological Activities in the Extract of Fermented Codonopsis lanceolata. J. Food Sci. Nutr., 38, 983-988.
  23. Peres, P.S., Terra, V.A., Guarnier, F.A., Cecchini, R. and Cecchini A.L. (2011). Photoaging and chronological aging profile: Understanding oxidation of the skin. J. Photochem. Photobiol. B., 103, 93-97. https://doi.org/10.1016/j.jphotobiol.2011.01.019
  24. Rittie, L. and Fisher, G.J. (2002). UV-light-induced signal cascades and skin aging. Ageing Res. Rev., 1, 705-720. https://doi.org/10.1016/S1568-1637(02)00024-7
  25. Shon, M.Y., Lee, J., Choi, J.H., Choi, S.Y., Nam, S.H., Seo, K.i., Lee, S.W., Sung, N.J. and Park, S.K. (2007). Antioxidant and free radical scavenging activity of methanol extract of chungkukjang. J. Food Compos., 20, 113-118. https://doi.org/10.1016/j.jfca.2006.08.003
  26. Trookman, N.S., Rizer, R.L., Ford, R., Ho, E. and Gotz, V. (2009). Immediate and long-term clinical benefits of a topical treatment for facial lines and wrinkles. J. Clin. Aesthet Dermatol., 2, 38-43.
  27. Wang, D., Wang, L.J., Zhu, J.Y., Chen, X.D., Zou, L., Satio, M. and Li, L.T. (2008). In vitro and in vivo studies on the antioxidant activities of the aqueous extracts of Douchi (a traditional Chinese salt-fermented soybean food). J. Food Chem., 107, 1421-1428. https://doi.org/10.1016/j.foodchem.2007.09.072
  28. Wang, H.L., Ruttle, D.I. and Hesseltine, C.W. (2011). Protein Quality of Wheat and Soybeans After Rhizopus oligosporus Fermentation . J. Nutrition., 96, 109-114.
  29. Yokozawa, T., Chen, C.P., Dong, E., Tanaka, T., Nonaka, G.I. and Nishioka, I. (1998). Study on the inhibitory effect of tannins and flavonoids againstthe1,1-diphenyl-2-picrylhydrazyl radical. Biochem Pharmacol., 56, 213-222. https://doi.org/10.1016/S0006-2952(98)00128-2
  30. Zhong, J., Hu, N., Xiong, X., Lei, Q. and Li, L. (2011). A novel promising therapy for skin aging: dermal multipotent stem cells against photoaged skin by activation of TGF-â/Smad and p38 MAPK signaling pathway. Med. Hypotheses, 76, 343-346. https://doi.org/10.1016/j.mehy.2010.10.035
  31. Zhu, N., Wang, M., Wei, G.J., Lin, J.K., Yang, C.S. and Ho, C.T. (2001). Identification of reaction products of (-)-epigallocatechin, (-)-epigallocatechin gallate and pyrogallol with 2,2-diphenyl-1 picrylhydrazyl radical. Food Chemistry, 73, 2345-2349.
  32. Zouboulis, C.C. and Makrantonaki, E. (2011). Clinical aspects and molecular diagnostics of skin aging. Clin. Dermatol., 29, 3-14. https://doi.org/10.1016/j.clindermatol.2010.07.001

Cited by

  1. Antioxidative and Antiaging Effects of Fermented Soybean, Rice Bran, and Red Ginseng by Mixed Ratios vol.28, pp.4, 2013, https://doi.org/10.13103/JFHS.2013.28.4.354
  2. Antihyperglycemic and Antihyperlipidemic Effects of Fermented Rhynchosia nulubilis in Alloxan-induced Diabetic Rats vol.29, pp.1, 2013, https://doi.org/10.5487/TR.2013.29.1.015
  3. Fermented Broth in Tyrosinase- and Melanogenesis Inhibition vol.19, pp.9, 2014, https://doi.org/10.3390/molecules190913122
  4. In vitro Antioxidant Effects of Sarijang vol.43, pp.4, 2014, https://doi.org/10.3746/jkfn.2014.43.4.618
  5. Melanogenesis-Promoting Effects of Rhynchosia nulubilis and Rhynchosia volubilis Ethanol Extracts in Melan-a Cells vol.32, pp.2, 2016, https://doi.org/10.5487/TR.2016.32.2.141
  6. Methanol Extract in Melan-a Cells vol.33, pp.1, 2017, https://doi.org/10.5487/TR.2017.33.1.055