Clinical application and classification of bone graft material according to component

임상가를 위한 특집 2 - 구성성분별 골이식재의 분류와 임상적용

  • Kim, Young-Kyun (Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital)
  • 김영균 (분당서울대학교병원 치과 구강악안면외과)
  • Received : 2010.03.23
  • Accepted : 2010.04.15
  • Published : 2010.04.01

Abstract

I classified the bone graft material according to the component. Most bone graft material is composed of inorganic and organic constituent. Organic component such DBM is associated with osteoinduction. Inorganic components such as hydroxyapatite, $\beta$-TCP, calcium sulfate, bioactive glass, polymer are associated with osteoconduction. Autogenous bone graft is ideal material. We can select any biocompatible material for the restoration of small filling defect with intact bony wall. However, we should select first osteogenetic and osteoinductive material to regenerate the viable bone tissue.

Keywords

References

  1. Kim YK. Systematic classification and application of alloplastic bony substitutes and sutogenous teeth bone graft material. The J Kor Acad Implant Dent. 2009; 28(2): 77-88.
  2. 2009 Autumn Congress of The Korean Academy of Implant Dentistry. Symposium.
  3. Min BM. Oral Biochemistry. Daehan Narae Pub Co. Seoul. 2007; 76-81.
  4. Lee SH. Low Crystalline hydroxyl carbonate apatite. J Korean Dent Assoc. 2006; 44(9): 524-533.
  5. 김형섭, 장윤혁, 이상훈 등. 아파타이트의 크기, 결정도 및 탄산기의 양이 골전도도에 미치는 영향. 한국생체재료학회지. 2005; 9: 193-197.
  6. Kim YK, Kim SG, Byeon JH, Lee HJ, Um IU, Lim SC, Kim SY. Development of a novel bone grafting material using autogenous teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jan 6. [Epub ahead of print]
  7. Wilkins R, Kelly CM, Giusti DE. Bioassayed demineralized bone matrix and calcium sulfate: Use in bone grafting procedures. Annales Chirurgiae et Gynaecologiae. 1999; 88: 180-185.
  8. Wilkins RM. Clinical effectiveness of demineralized bone matrix assayed in human cell culture. In Advances in Tissue Banking, Vol. 3 (G.O. Phillips, D.M. Strong, R. von Versen, A. Nather, eds) World Scientific Company, Singapore, 1999.
  9. Kim YK, Kim SG, Lee BG. Bone Graft and Implant. Vol. 1. Bone biology and bone graft material. Narae Pub Co. Seoul. 2007; 28-33.
  10. Kim YK, Lee JY. The evaluation of postoperative safety of autogenous teeth bone graft. The J Kor Acad Implant Dent. 2009; 28(2): 29-35.
  11. Young-Kyun Kim, Hyo-Jung Lee, Su-Gwan Kim, In-Woong Um, Sunc-Chul Lim, Suk-Young Kim: Analysis of inorganic component and SEM analysis of autogenous teeth bone graft material and histomorphometric analysis after graft. The J Korean Acad Implant Dent. 2009; 28(1): 1-9.
  12. Greenwald AS, Boden SD, Goldberg VM et al. Bone-graft substitutes: Facts, fictions & applications. American Academy of Orthopaedics surgeons. 70th Annual Meeting. Feb 5-9, 2003. New Orleans, Louisiana.
  13. Laurencin CT. Bone graft substitute materials. eMedicine Orthopedic Surg. Dec 3, 2009; 1-22.
  14. Jeong YM, Lee TH, Park JK et al. Bone Regeneration with Injectable MPEG-PCL Diblock Copolymer and Bone Marrow Mesenchymal Stem Cell. J Korean Assoc Maxillofac Plast Reconstr Surg. 2010; 32(1): 9-15.
  15. Lee J, Sung HM, Jang JD et al. Successful reconstruction of 15cm segmental defects by bone marrow stem cells and resected autogenous bone graft in central hemangioma. J Oral Maxillofac Surg. 2010; 68: 188-194. https://doi.org/10.1016/j.joms.2009.08.031
  16. Tadic D, Beckmann F, Donath T, Epple M. Comparison of different methods for the preparation of porous bone substitution materials and structural investigations by synchrotron ucomputer tomography. Mat.-wiss.u. Werkstofftech. 2004; 35(4): 240-244. https://doi.org/10.1002/mawe.200400730
  17. Tadic D, Epple M. A through physicochemical characterization of 14 calcium phosphate-based bone substitution materials in comparison to natural bone. Biomaterials. 2004; 25: 987-994. https://doi.org/10.1016/S0142-9612(03)00621-5