Journal of agriculture & life science (농업생명과학연구)

Institute of Agriculture & Life Science, Gyeongsang National University (경상대학교 농업생명과학연구원)
권호 표지

Effects of Fresh, Red and Black Garlic Powder on Lipid Metabolism of Obese Rats Induced by High Fat Diet

생마늘, 홍마늘 및 흑마늘 분말이 고지방 식이로 유도된 비만 흰쥐의 지질대사에 미치는 영향

  • Kim, Ra-Jeong (Dept. of Food Science and Nutrition(Insti. of Agric. & Life Sci.), Gyeongsang Nat'l Univ.) ;
  • Lee, Soo-Jung (Dept. of Food Science and Nutrition(Insti. of Agric. & Life Sci.), Gyeongsang Nat'l Univ.) ;
  • Kim, Mi-Joo (Dept. of Food Science and Nutrition(Insti. of Agric. & Life Sci.), Gyeongsang Nat'l Univ.) ;
  • Hwang, Cho-Rong (Dept. of Food Science and Nutrition(Insti. of Agric. & Life Sci.), Gyeongsang Nat'l Univ.) ;
  • Kang, Jae-Ran (Dept. of Food Science and Nutrition(Insti. of Agric. & Life Sci.), Gyeongsang Nat'l Univ.) ;
  • Jung, Woo-Jae (Namhae Garlic Research Institute) ;
  • Sung, Nak-Ju (Dept. of Food Science and Nutrition(Insti. of Agric. & Life Sci.), Gyeongsang Nat'l Univ., Namhae Garlic Research Institute)
  • 김라정 (경상대학교 식품영양학과(농업생명과학연구원)) ;
  • 이수정 (경상대학교 식품영양학과(농업생명과학연구원)) ;
  • 김미주 (경상대학교 식품영양학과(농업생명과학연구원)) ;
  • 황초롱 (경상대학교 식품영양학과(농업생명과학연구원)) ;
  • 강재란 (경상대학교 식품영양학과(농업생명과학연구원)) ;
  • 정우재 ((재)남해마늘연구소) ;
  • 성낙주 (경상대학교 식품영양학과(농업생명과학연구원), (재)남해마늘연구소)
  • Received : 2010.11.26
  • Accepted : 2010.12.22
  • Published : 2010.12.31
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Abstract

This study was aimed to evaluate the effects garlic such as fresh garlic powder (FGP), red garlic powder (RGP) and black garlic powder (BGP) by lyophilized, on serum lipid metabolism in obese rats induced high fat diet. Food efficiency ratio (FER) of the experimental groups was lower than the control group and it was significant difference. Total lipid content of serum decreased from 7.0 to 20.9% compared to the control group. Especially, triglyceride content decreased from 40.8% (BGP) to 42.1% (RGP) group as compared to the control group. There was no significant difference in HDL-C content between groups fed garlic powder and normal group. LDL-C contents of the experimental groups were lower than the control group, but has not showed significant diggerence compared to control group. Total lipid content was significantly increased in liver compared to the control group, but decreased over 30% in RGP and BGP groups to the control group. The lipid level in feces was increased by feeding periods of garlic powder, while total cholesterol and triglyceride were significantly increased in feces of RGP group. TBARS content in serum and liver of RGP and BGP groups was significantly decreased than the control group. Antioxidant activity of serum was 68.05% in the RGP group, which was significantly higher than the control group. From the above result, we suggested that red and black garlic powder were effective in the improvement of lipid level in obese rats induced high fat diet.

생마늘 (FGP), 홍마늘 (RGP) 및 흑마늘 (BGP)의 동결건조 분말을 각각 3%씩 비만 유도된 흰쥐에 4주간 혼합 급이한 후 혈청, 간 및 분변의 지질성분에 미치는 영향을 조사하였다. 식이효율은 마늘 분말 급이군이 대조군에 비하여 낮았으나 유의차는 없었다. 혈청 중 총 지질 함량은 대조군에 비해 7.0~20.9% 범위로 감소하였으며, 특히 중성지질 함량은 대조군에 비해 RGP군은 42.1%, BGP군은 40.8%정도로 유의적인 감소를 보였다. HDL-콜레스테롤 함량은 마늘 분말 급이시 정상군과 유사한 수준이었으며, LDL-콜레스테롤은 마늘 분말 급이시 감소되었으나 대조군과 유의차는 없었다. 간 조직의 총 지질은 대조군이 정상군에 비해 유의적으로 증가하였으나, RGP와 BGP 급이군에서 30%이상 감소되었다. 분변의 지질 함량은 마늘 분말의 급이 기간이 길수록 지질 함량이 높았으며, RGP군에서 총 콜레스테롤 및 중성지방의 배출이 유의적으로 증가되었다. 혈청과 간 조직의 TBARS 함량은 대조군에 비하여 RGP군과 BGP군에서 유의적으로 감소되었다. 항산화능은 혈청에서 RGP군이 68.1%로 대조군에 비하여 유의적으로 상승되었다. 이상의 결과로 고지방식이로 인해 비만이 유도된 흰쥐에게 홍마늘 및 흑마늘 분말을 급이는 체지방 증가 억제, 체내 지질 배출 증가 등에 의한 체내 지질 개선에 효과적인 것으로 사료된다.

Keywords

Acknowledgement

Supported by : 농림부

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