The Location and Size of Pulmonary Embolism in Antineoplastic Chemotherapy Patients

항암환자에서 발생한 폐색전증의 호발 혈관 위치 및 색전의 크기

  • Park, Yun-Joo (Department of Radiology, Wonju Christian Hospital, Yonsei University Wonju College of Medicine) ;
  • Kwon, Woo-Cheol (Department of Radiology, Wonju Christian Hospital, Yonsei University Wonju College of Medicine) ;
  • Lee, Won-Yeon (Department of Internal Medicine, Wonju Christian Hospital, Yonsei University Wonju College of Medicine) ;
  • Koh, Sang-Baek (Department of Prevent Medicine, Wonju Christian Hospital, Yonsei University Wonju College of Medicine) ;
  • Kim, Seong-Ah (Department of Radiology, Wonju Christian Hospital, Yonsei University Wonju College of Medicine) ;
  • Kim, Myung-Soon (Department of Radiology, Wonju Christian Hospital, Yonsei University Wonju College of Medicine) ;
  • Kim, Young-Ju (Department of Radiology, Wonju Christian Hospital, Yonsei University Wonju College of Medicine)
  • 박연주 (연세대학교 원주의과대학 원주기독병원 영상의학과) ;
  • 권우철 (연세대학교 원주의과대학 원주기독병원 영상의학과) ;
  • 리원연 (연세대학교 원주의과대학 원주기독병원 호흡기내과) ;
  • 고상백 (연세대학교 원주의과대학 원주기독병원 예방의학과) ;
  • 김성아 (연세대학교 원주의과대학 원주기독병원 영상의학과) ;
  • 김명순 (연세대학교 원주의과대학 원주기독병원 영상의학과) ;
  • 김영주 (연세대학교 원주의과대학 원주기독병원 영상의학과)
  • Received : 2009.08.06
  • Accepted : 2009.09.14
  • Published : 2010.07.01

Abstract

Purpose: To retrospectively evaluate the prevalent location and size of pulmonary embolism (PE) in anti-neoplastic chemotherapy patients by multidetector row CT (MDCT). Materials and Methods: This study was conducted on 101 patients that were positively diagnosed with PE by CT. Among these patients, 23 had received or were undergoing chemotherapy. The location and the mean size of the largest PE were compared between anti-neoplastic chemotherapy patients and non-cancer patients using the Chisquare test and paired t-test, respectively. We also used a multiple linear regression to assess the risk posed by the other risk factors of PE. Results: The most prevalent location of PE in patients on anti-neoplastic chemotherapy was in the lobar or segmental pulmonary arteries and was not significantly different from non-cancer patients. The size of the PE was smaller in patients on anti-neoplastic chemotherapy (1.14 mL [standard error = 0.29]) compared to non-cancer patients. (2.14 mL [standard error = 0.40]) (p < 0.05). Conclusion: The size of PE is smaller in anti-neoplastic chemotherapy patients than in non-cancer patients.

목적: 항암요법을 받는 환자에서 발생한 폐색전증의 호발 혈관 위치 및 색전의 크기를 다중 검출기 CT (MDCT)를 이용해 알아보고자 하였다. 대상과 방법: CT에서 폐색전증이 발견된 101명의 환자의 CT소견을 후향적으로 분석하였다. 이 중 23명은 항암요법을 받는 환자이다. 항암요법을 받는 환자와 비종양 환자의 가장 큰 폐색전의 발생 혈관 위치와 폐색전의 평균 크기를 교차분석 및 T-검정을 이용해 비교하였다. 폐색전증의 여러 가지 위험인자가 폐색전증의 호발 혈관 위치 및 색전의 크기에 미치는 영향을 고려하여 선형 회귀 분석을 통해 이를 바로잡았다. 결과: 항암요법을 받는 환자에서 폐색전증의 호발 혈관 위치는 엽성 또는 분절성 혈관이었으며 이는 비종양 환자와 통계학적으로 유의한 차이를 보이지 않았다. 폐색전증의 크기는 항암요법을 받는 환자에서 (1.14 mL [표준오차=0.29]) 비종양 환자보다 (2.14 mL [표준오차=0.40]) 통계학적으로 유의하게 작았다 (p < 0.05). 결론: 항암요법을 받는 환자에게서의 폐색전증의 크기는 비종양 환자보다 작다.

Keywords

References

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