DOI QR코드

DOI QR Code

A Transthoracic Echocardiographic Follow-Up Study After Catheter Ablation of Atrial Fibrillation: Can We Detect Pulmonary Vein Stenosis by Transthoracic Echocardiography?

  • Lee, Dong-Hyeon (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Oh, Yong-Seog (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Shin, Woo-Seung (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Kim, Ji-Hoon (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Choi, Yun-Seok (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Jang, Sung-Won (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Park, Chul-Soo (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Youn, Ho-Joong (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Lee, Man-Young (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Chung, Wook-Sung (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Seung, Ki-Bae (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Rho, Tai-Ho (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Kim, Jae-Hyung (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
  • Choi, Kyu-Bo (Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea)
  • Received : 2009.11.24
  • Accepted : 2010.03.30
  • Published : 2010.09.30

Abstract

Background and Objectives: While pulmonary vein isolation (PVI) is an effective curative procedure for patients with atrial fibrillation (AF), pulmonary vein (PV) stenosis is a potential complication which may lead to symptoms that are often unrecognized. The aim of this study was to compare differences between ablation sites in pulmonary venous flow (PVF) measured by transthoracic Doppler echocardiography (TTE) before and after PVI. Subjects and Methods: One hundred five patients (M : F=64 : 41; mean age 56${\pm}$10 years) with paroxysmal AF (n=78) or chronic, persistent AF (n=27) were enrolled. PVI strategies consisted of ostial ablation (n=75; OA group) and antral ablation using an electroanatomic mapping system (n=30; AA group). The ostial diameter was estimated by magnetic resonance imaging (MRI) in patients with PVF ${\geq}$110 cm/sec by TTE after PVI. Results: No patient complained of PV stenosis-related symptoms. Changes in mean peak right PV systolic (-6.7${\pm}$28.1 vs. 10.9${\pm}$25.9 cm/sec, p=0.038) and diastolic (-4.1${\pm}$17.0 vs. 9.9${\pm}$25.9 cm/sec, p=0.021) flow velocities were lower in the AA group than in the OA group. Although the change in mean peak systolic flow velocity of the left PV before and after PVI in the AA group was significantly lower than the change in the OA group (-13.4${\pm}$25.1 vs. 9.2${\pm}$22.3 cm/sec, p=0.016), there was no difference in peak diastolic flow velocity. Two patients in the OA group had high PVF velocities (118 cm/sec and 133 cm/sec) on TTE, and their maximum PV stenoses measured by MRI were 62.5% and 50.0%, respectively. Conclusion: PV stenosis after PVI could be detected by TTE, and PVI by antral ablation using an electroanatomic mapping system might be safer and more useful for the prevention of PV stenosis.

Keywords

References

  1. Jais P, Haissaguerre M, Shah DC, et al. A focal source of atrial fibrillation treated by discrete radiofrequency ablation. Circulation 1997; 95:572-6. https://doi.org/10.1161/01.CIR.95.3.572
  2. Haissaguerre M, Jais P, Shah DC, et al. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med 1998;339:659-66. https://doi.org/10.1056/NEJM199809033391003
  3. Kim YH. Rhythm control versus rate control of atrial fibrillation: pharmacologic and non-pharmacologic therapy. Korean Circ J 2003;33:553-8. https://doi.org/10.4070/kcj.2003.33.7.553
  4. Hong GR, Shin DG, Park JS, et al. Effects of pulmonary vein isolation using intraoperative radiofrequency catheter ablation for the treatment of atrial fibrillation associated with mitral valvular heart diseases. Korean Circ J 2002;32:596-603. https://doi.org/10.4070/kcj.2002.32.7.596
  5. Rha SW, Kim YH, Park HN, et al. Initiation and maintenance mechanism of atrial fibrillation assessed by 3-dimensional non-contact mapping system. Korean Circ J 2004;34:195-203. https://doi.org/10.4070/kcj.2004.34.2.195
  6. Robbins IM, Colvin EV, Doyle TP, et al. Pulmonary vein stenosis after catheter ablation of atrial fibrillation. Circulation 1998;98:1769-75. https://doi.org/10.1161/01.CIR.98.17.1769
  7. Scanavacca MI, Kajita LJ, Vieira M, Sosa EA. Pulmonary vein stenosis complicating catheter ablation of focal atrial fibrillation. J Cardiovasc Electrophysiol 2000;11:677-81. https://doi.org/10.1111/j.1540-8167.2000.tb00030.x
  8. Yu WC, Hsu TL, Tai CT, et al. Acquired pulmonary vein stenosis after radiofrequency catheter ablation of paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol 2001;12:887-92. https://doi.org/10.1046/j.1540-8167.2001.00887.x
  9. Ernst S, Ouyang F, Goya M, et al. Total pulmonary vein occlusion as a consequence of catheter ablation for atrial fibrillation mimicking primary lung disease. J Cardiovasc Electrophysiol 2003;14:366-70. https://doi.org/10.1046/j.1540-8167.2003.02334.x
  10. Saad EB, Rossillo A, Saad CP, et al. Pulmonary vein stenosis after radiofrequency ablation of atrial fibrillation: functional characterization, evolution and influence of the ablation strategy. Circulation 2003;108:3102-7. https://doi.org/10.1161/01.CIR.0000104569.96907.7F
  11. Haissaguerre M, Jais P, Shah DC, et al. Electrophysiological end point for catheter ablation of atrial fibrillation initiated from multiple pulmonary venous foci. Circulation 2000;101:1409-17. https://doi.org/10.1161/01.CIR.101.12.1409
  12. Arentz T, Jander N, von Rosenthal J, et al. Incidence of pulmonary vein stenosis 2 years after radiofrequency catheter ablation of refractory at-rial fibrillation. Eur Heart J 2003;24:963-9. https://doi.org/10.1016/S0195-668X(03)00002-2
  13. Pappone C, Rosanio S, Oreto G, et al. Circumferential radiofrequency ablation of pulmonary vein ostia: a new anatomic approach for curing atrial fibrillation. Circulation 2000;102:2619-28. https://doi.org/10.1161/01.CIR.102.21.2619
  14. Pappone C, Oreto G, Rosanio S, et al. Atrial electroanatomic remodeling after circumferential radiofrequency pulmonary vein ablation: efficacy of an anatomic approach in a large cohort of patients with atrial fibrillation. Circulation 2001;104:2539-44. https://doi.org/10.1161/hc4601.098517
  15. Pappone C, Rosanio S, Augello G, et al. Mortality, morbidity, and quality of life after circumferential pulmonary vein ablation for atrial fibrillation: outcomes from a controlled nonrandomized long-term study. J Am Coll Cardiol 2003;42:185-97. https://doi.org/10.1016/S0735-1097(03)00577-1
  16. Yu WC, Hsu TL, Tai CT, et al. Acquired pulmonary vein stenosis after radiofrequency catheter ablation of paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol 2001;12:887-92. https://doi.org/10.1046/j.1540-8167.2001.00887.x
  17. Packer DL, Stevens CL, Curley MG, et al. Intracardiac phased-array imaging: methods and initial clinical experience with high resolution, under blood visualization: initial experience with intracardiac phased-array ultrasound. J Am Coll Cardiol 2002;39:509-16. https://doi.org/10.1016/S0735-1097(01)01764-8
  18. Saad EB, Rossillo A, Saad CP, et al. Pulmonary vein stenosis after radiofrequency ablation of atrial fibrillation: functional characterization, evolution, and influence of the ablation strategy. Circulation 2003;108:3102-7. https://doi.org/10.1161/01.CIR.0000104569.96907.7F
  19. Jalife J, Berenfeld O, Mansour M. Mother rotors and fibrillatory conduction: a mechanism of atrial fibrillation. Cardiovasc Res 2002;54:204-16. https://doi.org/10.1016/S0008-6363(02)00223-7
  20. Jalife J. Rotors and spiral waves in atrial fibrillation. J Cardiovasc Electrophysiol 2003;14:776-80. https://doi.org/10.1046/j.1540-8167.2003.03136.x
  21. Hwang C, Wu TJ, Doshi RN, Peter CT, Chen PS. Vein of marshall cannulation for the analysis of electric activity in patients with focal atrial fibrillation. Circulation 2000;101:1503-5. https://doi.org/10.1161/01.CIR.101.13.1503
  22. Haissaguerre M, Jais P, Shah DC, et al. Electrophysiological end point for catheter ablation of atrial fibrillation initiated from multiple pulmonary venous foci. Circulation 2000;101:1409-17. https://doi.org/10.1161/01.CIR.101.12.1409
  23. Lin WS, Tai CT, Hsieh MH, et al. Catheter ablation of paroxysmal atrial fibrillation initiated by non-pulmonary vein ectopy. Circulation 2003;107:3176-83. https://doi.org/10.1161/01.CIR.0000074206.52056.2D
  24. Moe GK. A conceptual model of atrial fibrillation. J Electrocardiol 1968;1:145-6. https://doi.org/10.1016/S0022-0736(68)80020-2
  25. Stabile G, Turco P, La Rocca V, Nocerino P, Stabile E, De Simone A. Is pulmonary vein isolation necessary for curing atrial fibrillation? Circulation 2003;108:657-60. https://doi.org/10.1161/01.CIR.0000086980.42626.34
  26. Oral H, Scharf C, Chugh A, et al. Catheter ablation for paroxysmal atrial fibrillation: segmental pulmonary vein ostial ablation versus left atrial ablation. Circulation 2003;108:2355-60. https://doi.org/10.1161/01.CIR.0000095796.45180.88

Cited by

  1. Ablating Persistent Atrial Fibrillation Successfully vol.14, pp.5, 2010, https://doi.org/10.1007/s11886-012-0296-4