Korean Journal of Radiology

  • 제11권3호
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  • Pages.378-381
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  • 2010
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  • 1229-6929(pISSN)
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  • 2005-8330(eISSN)
대한영상의학회 (The Korean Society of Radiology)
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Imaging Findings in a Case of Mixed Acinar-Endocrine Carcinoma of the Pancreas

  • Chung, Won-Jung (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Byun, Jae-Ho (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Lee, Seung-Soo (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center) ;
  • Lee, Moon-Gyu (Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center)
  • 투고 : 2009.09.10
  • 심사 : 2009.12.07
  • 발행 : 2010.06.01
⟨ 이전 논문 다음 논문 ⟩

초록

Mixed acinar-endocrine carcinoma (MAEC) of the pancreas is extremely uncommon. We report here a rare case of MAEC of the pancreas presenting as watery diarrhea. This is the first report in the English-language literature that describes the imaging findings of MAEC of the pancreas, including computed tomography (CT), magnetic resonance (MR) imaging, and MR cholangiopancreatography features.

키워드

참고문헌

  1. Kamisawa T, Tu Y, Egawa N, Ishiwata J, Tsuruta K, Okamoto A, et al. Ductal and acinar differentiation in pancreatic endocrine tumors. Dig Dis Sci 2002;47:2254-2261 https://doi.org/10.1023/A:1020139328215
  2. Kloppel G. Mixed exocrine-endocrine tumors of the pancreas. Semin Diagn Pathol 2000;17:104-108
  3. Schron DS, Mendelsohn G. Pancreatic carcinoma with duct, endocrine, and acinar differentiation. A histologic, immunocytochemical, and ultrastructural study. Cancer 1984;54:1766-1770 https://doi.org/10.1002/1097-0142(19841101)54:9<1766::AID-CNCR2820540903>3.0.CO;2-4
  4. Ohike N, Kosmahl M, Kloppel G. Mixed acinar-endocrine carcinoma of the pancreas. A clinicopathological study and comparison with acinar-cell carcinoma. Virchows Arch 2004;445:231-235 https://doi.org/10.1007/s00428-004-1037-x
  5. Cubilla AL, Fitzgerald PJ. Cancer of the exocrine pancreas: the pathologic aspects. CA Cancer J Clin 1985;35:2-18 https://doi.org/10.3322/canjclin.35.1.2
  6. Yantiss RK, Chang HK, Farraye FA, Compton CC, Odze RD. Prevalence and prognostic significance of acinar cell differentiation in pancreatic endocrine tumors. Am J Surg Pathol 2002;26:893-901 https://doi.org/10.1097/00000478-200207000-00007
  7. Ballas KD, Rafailidis SF, Demertzidis C, Alatsakis MB, Pantzaki A, Sakadamis AK. Mixed exocrine-endocrine tumor of the pancreas. JOP 2005;6:449-454
  8. Klimstra DS, Rosai J, Heffess CS. Mixed acinar-endocrine carcinomas of the pancreas. Am J Surg Pathol 1994;18:765-778 https://doi.org/10.1097/00000478-199408000-00002
  9. Cubilla A, Fitzgerald PJ. Pancreas cancer. I. Duct adenocarcinoma. A clinical-pathologic study of 380 patients. Pathol Annu 1978;13:241-289
  10. Clark LR, Jaffe MH, Choyke PL, Grant EG, Zeman RK. Pancreatic imaging. Radiol Clin North Am 1985;23:489-501
  11. Choi YJ, Byun JH, Kim JY, Kim MH, Jang SJ, Ha HK, et al. Diffuse pancreatic ductal adenocarcinoma: characteristic imaging features. Eur J Radiol 2008;67:321-328 https://doi.org/10.1016/j.ejrad.2007.07.010
  12. Pamuklar E, Semelka RC. MR imaging of the pancreas. Magn Reson Imaging Clin N Am 2005;13:313-330 https://doi.org/10.1016/j.mric.2005.03.012
  13. Choi EK, Park SH, Kim DY, Kim KW, Byun JH, Lee MG, et al. Unusual manifestations of primary pancreatic neoplasia: radiologic-pathologic correlation. J Comput Assist Tomogr 2006;30:610-617 https://doi.org/10.1097/00004728-200607000-00010
  14. Tatli S, Mortele KJ, Levy AD, Glickman JN, Ros PR, Banks PA, et al. CT and MRI features of pure acinar cell carcinoma of the pancreas in adults. AJR Am J Roentgenol 2005;184:511-519 https://doi.org/10.2214/ajr.184.2.01840511
  15. Merkle EM, Bender GN, Brambs HJ. Imaging findings in pancreatic lymphoma: differential aspects. AJR Am J Roentgenol 2000;174:671-675 https://doi.org/10.2214/ajr.174.3.1740671
  16. Klein KA, Stephens DH, Welch TJ. CT characteristics of metastatic disease of the pancreas. Radiographics 1998;18:369- 378 https://doi.org/10.1148/radiographics.18.2.9536484

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  3. Peri-ampullary mixed acinar-endocrine carcinoma vol.3, pp.2, 2010, https://doi.org/10.4081/rt.2011.e15
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  6. Mixed Acinar-Endocrine Carcinoma of the Pancreas: New Clinical and Pathological Features in a Contemporary Series vol.42, pp.3, 2010, https://doi.org/10.1097/mpa.0b013e318264d073
  7. Clinical and CT imaging features of pancreatic acinar cell carcinoma vol.118, pp.5, 2013, https://doi.org/10.1007/s11547-012-0908-5
  8. A case of hyperfunctioning pancreatic mixed adenoneuroendocrine carcinoma (MANEC) arising from ectopic pancreatic tissue in the liver vol.9, pp.4, 2014, https://doi.org/10.2484/rcr.v9i4:1011
  9. Mixed acinar-endocrine carcinoma of pancreas: A case report and brief review of the literature vol.8, pp.None, 2015, https://doi.org/10.2147/ott.s87406
  10. A Rare Pancreatic Tumor That Underwent a Change in Morphology and Histopathologic Features During Chemotherapy vol.150, pp.2, 2016, https://doi.org/10.1053/j.gastro.2015.06.049
  11. Metastatic mixed acinar-endocrine carcinoma of the pancreas treated with a multidisciplinary approach: a case report vol.3, pp.None, 2017, https://doi.org/10.1186/s40792-017-0326-y
  12. Mixed Acinar-Endocrine Carcinoma (MAEC) Arising in Duodenal Pancreatic Heterotopia vol.2019, pp.None, 2010, https://doi.org/10.1155/2019/1713546
  13. A case of pancreatic mixed acinar-neuroendocrine carcinoma successfully diagnosed with endoscopic ultrasound-guided fine needle aspiration vol.13, pp.5, 2010, https://doi.org/10.1007/s12328-020-01136-1