Clinical Endoscopy

The Korean Society of Gastrointestinal Endoscopy (대한소화기내시경학회)
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A Case of Esophageal Lymphoepithelioma-like Carcinoma

식도에서 발생한 림프상피종양 암종 1예

  • Bahng, Sun-Ha (Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Jun-Haeng (Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Eun-Kyoung (Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Park, Sung-Bum (Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Park, Silvia (Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Kyoung-Mee (Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • 방선하 (성균관대학교 의과대학 서울삼성병원 내과학교실) ;
  • 이준행 (성균관대학교 의과대학 서울삼성병원 내과학교실) ;
  • 김은경 (성균관대학교 의과대학 서울삼성병원 내과학교실) ;
  • 박성범 (성균관대학교 의과대학 서울삼성병원 내과학교실) ;
  • 박실비아 (성균관대학교 의과대학 서울삼성병원 내과학교실) ;
  • 김경미 (성균관대학교 의과대학 서울삼성병원 병리학교실)
  • Received : 2010.04.12
  • Accepted : 2010.06.06
  • Published : 2010.07.30
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Abstract

Lymphoepithelioma-like carcinoma (LELC) of the esophagus is an extremely rare tumor and the prognosis is favorable. We present here a case an esophageal LELC that showed no definite progression for 5 years. An esophageal tumor was found during screening endoscopy for a 72-year-old asymptomatic Korean woman. At first the histology showed no abnormal findings. No treatment was done for the lesion. Five years later, a follow-up endoscopy showed the same tumor in the esophagus. The size and shape of the esophageal tumor seemed unchanged during the follow-up. The lesion was a round elevated lesion that measured approximately 2.5 cm in the lower esophagus. The covering mucosa looked smooth, but there were erosions on top of the tumor. Biopsy showed an undifferentiated carcinoma associated with a dense lymphocytic and plasma cell infiltration, which are typical findings of LELC.

식도의 림프상피종양 암종은 매우 드문 종양으로 미분화 암이지만 다른 조직형의 식도암에 비해서 예후가 좋다. 저자들은 5년간 뚜렷한 진행이 없었던 식도의 림프상피종양 암종을 진단하였다. 72세 여자 환자로 5년 전 증상 없이 시행한 상부 위장관 내시경에서 하부식도에 종양이 발견되었다. 첫 조직검사에서는 특별한 이상소견이 보고되지 않았으며 이에 대하여 특별한 치료는 받지 않았다. 5년 후 시행한 상부 위장관 내시경에서도 식도 종양이 발견되었고 크기 및 모양에 현저한 변화는 없었다. 하부식도의 약 2.5 cm 크기의 둥글게 융기된 병변으로 종양의 표면은 매끄러웠으나 중앙에 미란을 동반하고 있었다. 조직검사에서 림프상피종양 암종의 특징적인 소견인 풍부한 림프계세포들의 침윤이 동반된 미분화암의 형태를 보였다.

Keywords

References

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