NK-T cell lymphoma manifesting as acute respiratory distress syndrome

급성호흡곤란증후군으로 나타난 NK-T 세포 림프종

  • Jeong, Eun-Seon (Department of Internal Medicine, Inha University School of Medicine) ;
  • Joo, Ko-Woon (Department of Internal Medicine, Inha University School of Medicine) ;
  • Kim, Jung-Soo (Department of Internal Medicine, Inha University School of Medicine) ;
  • Min, Kyung-Sun (Department of Internal Medicine, Inha University School of Medicine) ;
  • Choi, Seok-Jin (Department of Pathology, Inha University School of Medicine) ;
  • Nam, Hae-Sung (Department of Internal Medicine, Inha University School of Medicine) ;
  • Cho, Jae-Hwa (Department of Internal Medicine, Inha University School of Medicine)
  • 정은선 (인하대학교 의학전문대학원 내과학교실) ;
  • 주고운 (인하대학교 의학전문대학원 내과학교실) ;
  • 김정수 (인하대학교 의학전문대학원 내과학교실) ;
  • 민경선 (인하대학교 의학전문대학원 내과학교실) ;
  • 최석진 (인하대학교 의학전문대학원 병리학교실) ;
  • 남해성 (인하대학교 의학전문대학원 내과학교실) ;
  • 조재화 (인하대학교 의학전문대학원 내과학교실)
  • Received : 2009.09.30
  • Accepted : 2010.01.21
  • Published : 2010.12.01

Abstract

Primary pulmonary lymphoma is a rare disease, and non-B cell lymphomas (T-cell and natural killer cell lymphomas) involving the lung parenchyma are uncommonly reported. The most common radiological feature of pulmonary parenchymal lymphoma is a single mass or nodule. A 49-year-old woman with dyspnea was referred with suspicion of severe pneumonia. A chest radiograph showed diffuse nodular infiltration in both lungs. Acute respiratory failure was severe and rapidly progressive, so she was managed with a mechanical ventilator under the impression of acute respiratory distress syndrome (ARDS). A bronchoalveolar lavage and lung biopsy by video-assisted thoracic surgery revealed NK-T cell lymphoma. We report a case of extranodal NK-T cell lymphoma presenting as ARDS.

양측성 폐침윤을 보인 49세 여자에서 항생제 복합투여에도 상태가 더욱 악화되고 급성호흡곤란증후군으로 진행하였다. 폐병변의 원인을 밝히기 위하여 기관지 폐포 세척 및 폐생검을 시행하였고, NK-T 세포 림프종을 진단하여 보고하는 바이다.

Keywords

Acknowledgement

Supported by : INHA

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