The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지

Endoscopic botulinum toxin injection in cricopharyngeal dysphagia

내시경적 보툴리눔 독소 주입으로 치료한 윤상인두근이상증 1예

  • Jung, Kyo-Tae (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Choi, Hong-Kyu (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Lee, Ki-Byung (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Yu, Jung-Hwan (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Jie-Hyun (Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Park, Yoon-Ghil (Department of Rehabilitation Medicine, Yonsei University College of Medicine) ;
  • Lee, Sang-In (Department of Internal Medicine, Yonsei University College of Medicine)
  • 정교태 (연세대학교 의과대학 내과학교실) ;
  • 최홍규 (연세대학교 의과대학 내과학교실) ;
  • 이기병 (연세대학교 의과대학 내과학교실) ;
  • 유정환 (연세대학교 의과대학 내과학교실) ;
  • 김지현 (연세대학교 의과대학 내과학교실) ;
  • 박윤길 (연세대학교 의과대학 재활의학교실) ;
  • 이상인 (연세대학교 의과대학 내과학교실)
  • Received : 2009.09.21
  • Accepted : 2009.10.09
  • Published : 2010.09.01
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Abstract

Botulinum toxin has been used to treat various gastrointestinal tract diseases such as achalasia, diabetic gastroparesis, sphincter of oddi dysfunction, and chronic anal fissures. Recently, it has also been used for the treatment of cricopharyngeal muscle dysfunction. Several studies have reported that botulinum toxin injections may be a safe and effective treatment. Previously, cricopharyngeal muscle dysfunction was treated by mechanical balloon dilation or cricopharyngeal myotomy. Here, we report a case of a 57-year-old man who presented with cricopharyngeal dysphagia due to cerebral infarction and who was successfully treated with endoscopic botulinum toxin injection.

보툴리눔 독소는 아칼라지아, 당뇨병성 위마비, 오디괄약근 장애, 만성 항문치열 등 다양한 소화기 질환에 사용되고 있다. 윤상인두근 기능이상은 이전에는 기계적 풍선 확장술이나 윤상인두근 절제술로 치료하였으나, 최근 윤상인두근 내 보툴리눔 독소 주입에 의해 안전하고 효과적으로 치료될 수 있음이 보고되고 있다. 본 환자는 뇌졸중에 의한 윤상인두근 장애로 연하곤란을 호소하였으며, 내시경적 보툴리눔 독소주입 이후 호전을 보였기에 이를 보고하는 바이다.

Keywords

References

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