The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지

A case of Graves' disease associated with myasthenia gravis and complicated with moyamoya disease

병발된 그레이브스병과 중증근무력증 환자에서 진단된 모야모야병 1예

  • Back, Ji-Hoon (Department of Internal Medcine, Presbyterian Medical Center) ;
  • Kang, Hye-Mi (Department of Internal Medcine, Presbyterian Medical Center) ;
  • Min, Byeng-Do (Department of Internal Medcine, Presbyterian Medical Center) ;
  • Gil, So-Hyun (Department of Internal Medcine, Presbyterian Medical Center) ;
  • Kim, Su-Jeung (Department of Radiology, Presbyterian Medical Center) ;
  • Oh, Byoung-Chul (Department of Neurology, Presbyterian Medical Center) ;
  • Kim, Ji-Hye (Department of Internal Medcine, Presbyterian Medical Center)
  • Received : 2009.09.08
  • Accepted : 2009.09.10
  • Published : 2010.08.01
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Abstract

Moyamoya disease (MMD) is a cerebrovascular disorder characterized by bilateral stenosis or occlusion of the terminal portions of the internal carotid arteries. MMD is also accompanied by typical net-like collateral vessels in the basal ganglia. Although the etiology of MMD remains unknown, hereditary, immunogenic, and hemodynamic factors have been implicated as underlying mechanisms of MMD. Here, the authors report on one patient with a rare combination of Graves' disease-associated thyrotoxicosis, myasthenia gravis, and MMD, where cerebrovascular ischemic events occurred during a thyrotoxic state.

중증근무력증과 그레이브스병이 동시 발병한 30세 여자환자에서 대뇌허혈 증상 발생으로 모야모야병을 진단하고 항갑상샘 약물치료와 혈관문합술을 시행한 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. 중증근무력증의 근위약과 모야모야병에 의한 대뇌허혈 증상을 예방하기 위해 동반된 그레이브스병에서의 갑상샘기능 안정화가 중요한 치료 전략으로 고려되어야 한다.

Keywords

References

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