An Empirical Study on Quantitative Evaluation of Cognitive Function

인지기능의 정량적 평가를 위한 측정 모델 소프트웨어 개발 및 실험적 검증 연구

  • Ryu, Wan-Seok (Department of Computer Engineering, Korea Polytechnic University) ;
  • Kim, Hyung-Gun (Department of Internal Medicine, The University of Texas Health Science Center at Houston) ;
  • Chung, Sung-Taek (Department of Computer Engineering, Korea Polytechnic University)
  • Received : 2009.12.28
  • Accepted : 2010.02.03
  • Published : 2010.03.31

Abstract

Imaging studies using MRI, PET, and/or MEG have been primary evaluation methods to quantitatively assess cognitive function. Recent advances in computational technology and information technology may allow a novel evaluation methodology to quantitate cognitive function more cost-effectively. In this study, we developed a software package composed of a series of tests to evaluate cognitive ability combined with a user-friendly touch screen input device. This cognitive assessment tool can quantitate concentration, numeric memory, associative memory, topological memory, visual and muscular reaction, and acoustic reaction over a relatively short testing time. We performed an empirical study on eighty normal subjects aged 20 and 59 years old using the developed evaluation methods. Age-related cognitive deterioration after 40 years old was confirmed. There was no difference in cognitive ability between male and female in the same age group. This study demonstrates the feasibility of a simple but effective evaluation software tool to quantitatively assess cognitive ability. This methodology may provide improved accessibility and reduced costs to perform cognitive function studies to compare between various subject groups.

뇌 기능 연구 분야에서는 MRI, PET, MEG 영상 시스템 등을 이용한 인지기능에 대한 정량적 평가 연구가 계속적으로 이루어 지고 있다. 최근에는 컴퓨터 기술을 응용하여 인지 기능의 정량적 분석을 효과적으로 하고자 시도되고 있다. 본 연구에서는 터치 스크린을 이용하여 인지 기능의 정량적 평가를 할 수 있는 소프트웨어 패키지를 구현하였다. 여기서 구현된 내용은 집중력, 숫자 기억력, 조합 기억력, 위상 기억력, 시각 및 근육 반응, 청각 반응 등으로 되어 있다. 우리는 구현된 소프트웨어에 대하여 실험적 검증과정을 거치고자 20~59세까지의 연령 및 성별에 따른 80명을 대상으로 실험을 수행하였다. 남녀 모두 40세 이후의 연령에서 인지기능의 감쇄가 일어나는 결과를 정량적 획득하였다. 본 연구에서는 고가 장비인 영상 시스템뿐만 아니라 상대적으로 간소화된 소프트웨어를 이용하여서도 인지기능의 정량적 평가가 가능함을 보여주고 있다. 이러한 방법을 적용하여 다양한 그룹의 인지 기능의 정량적 평가 및 비교를 수행하는 데 비용과 시간을 줄일 수 있을 것으로 보인다.

Keywords

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