Journal of Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Antioxidant and Quinone Reductase Inductive Activities of Various Organs of Pepper

고추 기관별 항산화 활성과 quinone reductase 유도활성

  • Ku, Kang-Mo (Division of Applied Biosciences, College of Agriculture and Life Science, Kyungpook National University) ;
  • Kang, Young-Hwa (Division of Applied Biosciences, College of Agriculture and Life Science, Kyungpook National University)
  • 구강모 (경북대학교 농업생명과학대학 응용생명과학부) ;
  • 강영화 (경북대학교 농업생명과학대학 응용생명과학부)
  • Received : 2009.09.17
  • Accepted : 2009.11.05
  • Published : 2010.03.31
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Abstract

We analyzed antioxidant and quinone reductase (QR) inductive activities of various organs of pepper for utilizing by-product of them. Peppers were separated into fruits, roots, stems, and leaves and extracted with methanol for the analysis. As a result, pepper leaves showed higher phenol content than other organs. Using the DPPH assay, there was not considerably different activity depending on pepper organs, but pepper leaves showed significantly higher antioxidant activity using the ABTS assay. In FTC and TBA assay, stems and leaves showed significantly higher lipidperoxidation inhibitory activity. In QR inductive assay, pepper tissues showed different QR inductive activity: leaves>roots>>stems>fruits. In addition, pepper leaves showed highest antiproliferation activity on hepa1c1c7 among pepper tissues in $50-200\;{\mu}g/mL$. These results indicate that pepper leaves have high potential to be a good functional food material due to high QR inductive and antioxidant activities.

고추 부산물의 활용을 위해 고추의 각 기관별 추출물에 대한 항산화와 QR 유도 활성을 측정하였다. 고추의 과실, 뿌리, 줄기, 잎을 각각 메탄올로 추출하여 분석한 결과, 고춧잎이 다른 기관에 비해 플라보노이드와 페놀성분이 높은 것으로 나타났다. DPPH 항산화 실험에서는 기관별로 큰 차이가 없었던 반면, ABTS 항산화 실험에서는 고춧잎이 다른 기관에 비해 유의적으로 높은 항산화능을 보였다. FTC와 TBA 실험에서 줄기와 고춧잎이 다른 기관에 비해 유의하게 높은 지질과산화 억제능을 나타냈다. QR 유도활성에서는 고춧잎, 뿌리, 줄기, 과실순으로 높았다. 고춧잎의 경우 $50-200\;{\mu}g/mL$ 농도에서는 다른 기관에 비해 높은 세포 성장 억제능을 보였다. 결론적으로 고춧잎은 다른 기관에 비해 항산화 활성과 QR 유도 활성이 높아 기능성소재로서의 활용가치가 높다.

Keywords

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