Clinical and Experimental Reproductive Medicine

  • 제37권1호
  • /
  • Pages.83-88
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  • 2010
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  • 2233-8233(pISSN)
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  • 2233-8241(eISSN)
대한생식의학회 (The Korean Society for Reproductive Medicine)
권호 표지

Globozoospermia를 가진 불임환자에서 미세정자주입술을 이용한 체외수정시술 후 임신과 분만 1례 보고

Successful Clinical Pregnancy and Livebirth was Achieved after Intracytoplasmic Sperm Injection in a Globozoospermic Patient: A Case Report

  • 김은경 (차의과대학교 분당차여성병원) ;
  • 김은하 (차의과대학교 분당차여성병원) ;
  • 김은아 (차의과대학교 분당차여성병원) ;
  • 권황 (차의과대학교 분당차여성병원) ;
  • 홍재엽 (차의과대학교 분당차여성병원) ;
  • 최동희 (차의과대학교 분당차여성병원)
  • 발행 : 2010.03.31
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⟨ 이전 논문 다음 논문 ⟩

초록

목 적: Globozoospermia는 남성불임환자의 0.1%에서 발병되는 극히 드문 정자의 형태학적 이상 증상으로 본원에서 이 증례를 경험하여 문헌고찰과 함께 보고하는 바이다. 연구방법: 2회 반복적 임신에 실패한 불임기간은 6년인 32세의 부인, 36세의 남편 부부가 본원에 내원하였으며, 정액 특수염색결과 희소정자증을 동반한 globozoospermia로 판별이 되어 미세정자주입시술을 실시하였다. 결 과: 14개의 난자가 회수되었으며 이 중 총 12개를 미세정자주입시술을 이용 수정시도를 하였고, 이 중 5개가 수정이 되어 3일 배양 후 이식하였다. 이식 결과 임신이 되었으며, 임신 39주에 건강한 남아를 출산하였다. 결 론: Globozoospermia의 경우 ICSI(미세정자주입시술)방법을 실시하더라도 수정율이 낮다. 이에 수정율 및 임신율을 높일 수 있는 방법의 개발이 필요한 것으로 사료된다.

Objective: Globozoospermia is observed in <0.1% of male infertile patients. The aim of this study is to report the successful clinical outcome in man with globozoospermia. Design: A case report. Method: A 36-year-old man and 32-year-old partner visited our fertility center with 6 years infertility duration. The semen analysis revealed globozoospermia combined with oligozoospermia which was stained with Diff-Quick method. ICSI (Intracytoplasmic sperm injection) was performed on 12 matured oocytes. Result: 5 injected oocytes were fertilized normally. 5 embryos were transferred on day 3 after oocyte retrieval. The patient became pregnant and delivered a healthy boy at 39 weeks of gestation. Conclusion: In case of globozoospermia, it has a low fertilization rate even though ICSI method is used. The favorable technique is still needed to increase the fertilization rate.

키워드

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