The Treatment of Hemangioma in Lower Lip

하순에 발생한 혈관종 환자의 치험례

  • Lee, Eun-Young (Department of Oral and Maxillofacial Surgery, College of Medicine and Medical Research Institute, Chungbuk National University) ;
  • Kim, Kyoung-Won (Department of Oral and Maxillofacial Surgery, College of Medicine and Medical Research Institute, Chungbuk National University) ;
  • Lee, Ji-Yeoun (Department of Dermatology, College of Medicine and Medical Research Institute, Chungbuk National University)
  • 이은영 (충북대학교 의과대학 구강악안면외과학교실) ;
  • 김경원 (충북대학교 의과대학 구강악안면외과학교실) ;
  • 이지연 (충북대학교 의과대학 피부과학교실, 의학연구소)
  • Received : 2010.02.09
  • Accepted : 2010.05.04
  • Published : 2010.07.30

Abstract

Vascular anomalies are common birthmarks. A eight-month-old male infant had a small size, bright red swelling on the lower lip since birth. On cutaneous examination there was a small brightly erythematous, lobulated, soft plaque on the left side of the lower lip of $10{\times}8{\times}5$ mm. Ultrasonogram examination revealed the lesion and confirmed the diagnosis of capillary hemangioma. The decision to initiate treatment is based on many factors, including size, location and risks and benefits of the proposal therapy. Systemic corticosteroids are decided to prevent the scarring and deforming. Prednisolone was given at a dose of 2 mg/kg/day for 2 weeks followed by tapering for 6 weeks for treatment. After eight weeks there was 80% reduction in the size of the lesion and the left lower lip almost completely cleared without intraoral bleeding. Furthermore, intervention by way of systemic steroids, laser therapy or surgical debulking is appropriate and safe in a select group of patients presenting with a proliferating hemangioma. This report describes a case that was sucessfully treated by systemic steroid therapy for hemangima in intraoral region.

Keywords

References

  1. Watson WL, McCarthy WD : Blood and Lymph Vessel Tumors - A report of 1,056 cases. Surg Gynecol Obstet 71 : 569, 1940.
  2. Wolff K, Goldsmith LA, Katz SI et al : Fitzpatrick's Dermatology in general medicine. 7th ed. New York, Mc Graw Hill, 2003, p.1164.
  3. Friedlander AH, Zeff S : Sclerosing Hemangioma of tongue - Report of Case. J Oral Surg 33 : 212, 1975.
  4. Brucker AL, Frieden IJ : Hemangiomas of infancy. J Am Acad Dermatol 48 : 477, 2003. https://doi.org/10.1067/mjd.2003.200
  5. Enjolras O, Mulliken JB : Vascular tumors and vascular malformations(new issues). Adv Dermatol 13 : 375, 1998.
  6. Lampe I, Latourette HB : The management of cavernous hemangiomas in infants. Postgrad Med 19 : 262, 1956. https://doi.org/10.1080/00325481.1956.11708295
  7. Bowers RE, Graham EA, Tomlinson KM : The natural history of the strawberry nevus. Arch Dermatol 82 : 667, 1960. https://doi.org/10.1001/archderm.1960.01580050009002
  8. Finn MC, Glowacki J, Mulliken JB : Congenital vascular lesions : clinical application of a new classification. J Pediatr Surg 18 : 894, 1983. https://doi.org/10.1016/S0022-3468(83)80043-8
  9. Frieden IJ : Which hemangiomas to treat-and how? Arch Dermatol 133 : 1593, 1997. https://doi.org/10.1001/archderm.133.12.1593
  10. Frieden IJ, Eichenfield LF, Esterly NB et al : Guidelines of care for hemangiomas of infancy. J AmAcad Dermatol 37 : 631, 1997. https://doi.org/10.1016/S0190-9622(97)70183-X
  11. Kim HJ, Colombo M, Frieden IJ : Ulcerated hemangiomas : clinical characteristics and response to therapy. J AmAcad Dermatol 44 : 962, 2001. https://doi.org/10.1067/mjd.2001.112382
  12. Enjolras I, Riche MC, Merland JJ et al : Management of alarming hemangiomas in infancy: a review of 25 cases. Pediatrics 85 : 491, 1990.
  13. Zarem HA, Edgerton MT : Induced resolution of cavernous hemangiomas following prednisolone therapy. Plast Reconstr Surg 39 : 76, 1967. https://doi.org/10.1097/00006534-196701000-00010
  14. Bennett ML, Fleischer AB, Chamlin SL et al : Oral corticosteroid use is effective for cutaneous hemangiomas. Arch Dermatol 137 : 1208, 2001.
  15. Blei F, Chianese J : Corticosteroid toxicity in infants treated for endangering hemangiomas: experience and guidelines for monitoring. Int Pediatr 14 : 146, 1999.
  16. Elsas FJ, Lewis AR : Topical treatment of periocular capillary hemangioma. J Pediatr Ophthalmol Strabismus 31 : 153, 1994.
  17. Dubois J, Hershon L, Carmant L et al : Toxicity profile of interferon alfa-2b in children: a prospective evaluation. J Pediatr 135 : 782, 1999. https://doi.org/10.1016/S0022-3476(99)70104-6
  18. Scheepers JH, Quaba AA : Does the pulsed tunable dye laser have a role in the management of infantile hemangiomas? Observations based on 3 years' experience. Plast Reconstr Surg 95 : 305, 1995. https://doi.org/10.1097/00006534-199502000-00010