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Consideration for treatment of bisphosphonate-related osteonecrosis of the jaw

Bisphosphonate-related osteonecrosis of jaw의 치료에 대한 고찰

  • You, Kyung-Ha (Department of Oral and Maxillofacial Surgery, Inje University Sanggye Paik Hospital) ;
  • Yoon, Kyu-Ho (Department of Oral and Maxillofacial Surgery, Inje University Sanggye Paik Hospital) ;
  • Bae, Jung-Ho (Department of Oral and Maxillofacial Surgery, Inje University Sanggye Paik Hospital) ;
  • Park, Jae-An (Department of Oral and Maxillofacial Surgery, Inje University Sanggye Paik Hospital) ;
  • Park, Gun-Chan (Department of Oral and Maxillofacial Surgery, Inje University Sanggye Paik Hospital) ;
  • Shin, Jae-Myung (Department of Oral and Maxillofacial Surgery, Inje University Ilsan Paik Hospital) ;
  • Baik, Jee-Seon (Department of Oral and Maxillofacial Surgery, Inje University Ilsan Paik Hospital) ;
  • Cheong, Jeong-Kwon (Department of Oral and Maxillofacial Surgery, Inje University Sanggye Paik Hospital)
  • 유경하 (인제대학교 상계백병원 구강악안면외과학교실) ;
  • 윤규호 (인제대학교 상계백병원 구강악안면외과학교실) ;
  • 배정호 (인제대학교 상계백병원 구강악안면외과학교실) ;
  • 박재안 (인제대학교 상계백병원 구강악안면외과학교실) ;
  • 박군찬 (인제대학교 상계백병원 구강악안면외과학교실) ;
  • 신재명 (인제대학교 일산백병원 구강악안면외과학교실) ;
  • 백지선 (인제대학교 일산백병원 구강악안면외과학교실) ;
  • 정정권 (인제대학교 상계백병원 구강악안면외과학교실)
  • Received : 2010.03.22
  • Accepted : 2010.05.20
  • Published : 2010.06.30

Abstract

Bisphosphonates are widely used to treat osteoporosis, hypercalcemia of malignant tumor. Despite their clinical benefit, bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a newly documented complication to patients receiving these drugs and first recognized by Marx in 2003. Thus, consideration of prevention and needs regarding unequivocal treatment regimen have emerged. Recently, several authors emphasized reports on appropriate clinical availability of surgical approach. It serves to concern about guideline for surgical and conservative treatment modalities. So, it is the purpose of this paper to review the current literatures about treatment regimens of BRONJ.

Keywords

References

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