The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Clinical Study of Antibiotic-associated Diarrhea Treatment in Intensive Care Unit Patients at an Oriental Hospital

한방병원 중증치료실 입원 중 항생제 연관성 설사를 진단받은 환자에 대한 임상적 고찰

  • Yang, Ga-Eun (Dept. of Oriental Internal Medicine, College of Oriental Medicine, Kyung-Hee University) ;
  • Kim, Seul-Ji (Dept. of Oriental Internal Medicine, College of Oriental Medicine, Kyung-Hee University) ;
  • Park, Young-Ju (Dept. of Oriental Internal Medicine, College of Oriental Medicine, Kyung-Hee University) ;
  • Lee, Mi-Jung (Dept. of Oriental Internal Medicine, College of Oriental Medicine, Kyung-Hee University) ;
  • Lee, Jee-Sook (Dept. of Oriental Internal Medicine, College of Oriental Medicine, Kyung-Hee University) ;
  • Ryu, Jae-Hwan (East-west medicine department, Graduate school of east-west medical science, Kyung-hee University)
  • 양가은 (경희대학교 한의과대학 내과학교실) ;
  • 김슬지 (경희대학교 한의과대학 내과학교실) ;
  • 박영주 (경희대학교 한의과대학 내과학교실) ;
  • 이미정 (경희대학교 한의과대학 내과학교실) ;
  • 이지숙 (경희대학교 한의과대학 내과학교실) ;
  • 류재환 (경희대학교 동서의학대학원 동서의학과)
  • Published : 2010.06.30
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Abstract

Objectives : This study was designed to investigate the effectiveness of adjunctive herbal therapy combined with conventional therapy on antibiotic-associated diarrhea (AAD) treatment. Methods : The medical records of 25 patients admitted to the Intensive Care Unit at Kyunghee Oriental Medical Center between January 1, 2009 and January 30, 2010 were reviewed. The charts were analyzed for the general characteristics, site of infection, predominant bacteria, antibiotic treatment, herbal medicine treatment, effect on liver and kidney functions, and the effect of therapy on diarrheal duration. Results : 48% of the 25 patients were male while 52% were female. The average age was 67.2 years old. The most commonly used antibiotic was fluoroquinolone (40.0%) and the most commonly used herbal medicine was Samchulkunbi-tang (24.0%). The average diarrheal duration was 8.9 days. No significant change in hepatic and renal function was discovered before and after treatment with herbal medicine. Conclusions : The results suggest that herbal therapy would be a safe and effective treatment for AAD. Further study investigating the usage of herbal medicine in AAD treatment is anticipated.

Keywords

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