방사선 조사된 골수복제의 저장 안전성 평가

Study on the Storage Stability of Xeno-Bone Graft Material by Irradiation

  • 이학증 (한국원자력연구원 정읍방사선과학연구소) ;
  • 김재훈 (한국원자력연구원 정읍방사선과학연구소) ;
  • 김태운 (리온테크놀로지) ;
  • 이주운 (한국원자력연구원 정읍방사선과학연구소) ;
  • 최종일 (한국원자력연구원 정읍방사선과학연구소)
  • Lee, Hak-Jyung (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Kim, Jae-Hun (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Kim, Tae-woon ;
  • Lee, Ju-Woon (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute) ;
  • Choi, Jong-il (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute)
  • 투고 : 2010.11.30
  • 심사 : 2010.12.06
  • 발행 : 2010.12.30

초록

In this study, the microbial safety and mechanical properties of xeno-bone graft material irradiated were investigated during the storage. Xeno-bone graft of the deminerlized bone matrix in carboxy-methyl-cellulose was gamma-irradiated and was cultured in PCA and PDA agar to check microbial contamination. Total aerobic bacteria and fungi were not detected in the irradiated and non-irradiated sample stored in accelerator at $30^{\circ}C$ for 10 months. Viscosity of CMC treated gamma irradiation was also not changed by holding period.

키워드

과제정보

연구 과제 주관 기관 : 한국원자력연구원