A Study on Chinese Herb Medicine Treatment of Cancer Cachexia to Chinese Journals

암성 악액질(cancer cachexia)의 한약치료에 대한 고찰 -2000~2009년까지 중의논문을 중심으로-

  • Song, Kwang-Kyu (Division of Internal Medicine, College of Oriental Medicine, Daegu Haany University) ;
  • Park, Mee-Yeon (Division of Internal Medicine, College of Oriental Medicine, Daegu Haany University) ;
  • Choi, Hae-Yun (Division of Internal Medicine, College of Oriental Medicine, Daegu Haany University) ;
  • Kim, Jong-Dae (Division of Internal Medicine, College of Oriental Medicine, Daegu Haany University)
  • 송광규 (대구한의대학교 한의학과 내과학교실) ;
  • 박미연 (대구한의대학교 한의학과 내과학교실) ;
  • 최해윤 (대구한의대학교 한의학과 내과학교실) ;
  • 김종대 (대구한의대학교 한의학과 내과학교실)
  • Received : 2010.06.29
  • Accepted : 2010.07.29
  • Published : 2010.08.31

Abstract

Objetcives : Cancer cachexia is a common syndrome in advanced cancer patients, which is characterized by profound changes in protein, fat and carbohydrate metabolism, resulting in anorexia, weight loss, muscle wasting and poor performance status. We studied the journals of Chinese herb medicine about cancer cachexia and reported the results. Methods : This study attempted to analyze the contents of the research papers concerning the treatment of cancer cachexia presented in the journals of Chinese medicine published in China over the period between 2000 and 2009. Results & Conclusions : The principles for medical treatment were invigorating Ki(益氣), invigorating the spleen(健脾), regulating the stomach(和胃), nourishing the blood(養血), nourishing Eum(補陰), promoting the circulation of Ki(行氣), removing the phlegm(化痰), removing blood stasis(祛瘀) etc. The used herbs were Poria(茯笭), Astragali Radix(黃芪), Atractylodis Macrocephalae Rhizoma(白朮), Codonopsis Pilosulae Radix(黨蔘), Dioscoreae Rhizoma(山藥), Citri Pericarpium(陳皮), Angelicae Gigantis Radix(當歸), Coicis Pemen(薏苡仁), Paeoniae Radix Alba(白芍藥) etc. The effetcive rate of treatment with Chinese herb medicine group was comparable or even more effetcive. Chinese herb medicine group had little side effetcs. Chinese medicine herb treatment to inhibit cancer cachexia has many possibilities.

Keywords

References

  1. Nelson KA. Walsh D. Sheehan FA. The canceranorexia-cachexiz syndrome. J. of Clinical Oncology.1994;12(1):213-225.
  2. 김은경, 양영희, 최스미. 입원한 암환자의 영양상태연구. 대한간호학회지. 1999; 29(2):271-280.
  3. 翁家武, 陳培豊. 癌症惡病質的中醫藥治療硏究進展. 浙江中西醫結合雜誌. 2009;19(2):123-125.
  4. 김복자, 김연희, 전명희, 최전선 외 편저. 암환자 간호증상 관리. 서울:현문사. 2000:439-478.
  5. 왕수경, 윤은영, 박정민, 임종순, 김승형. 혼합한약재가 악액질이 유도된 생쥐의 cytokine 분비 및 식이섭취와 영양대사에 미치는 영향. 한국영양학회지. 2003;36(4):368-375.
  6. 張靜. 中藥對癌症患者惡病質狀態的影響. 中國中西醫結合雜誌, 2000;20(11):871.
  7. 王守峰, 張峰. 中醫辨證配合小劑量化療治療晚期原發性肝癌療效觀察. 內蒙古中醫藥, 2000;19(4):2.
  8. 陳衍智, 李萍萍, 郭慶志. 中藥合并醋酸甲羥孕酮改善晚期癌症患者惡病質. 中國腫瘤臨床與康復, 2002;9(4):119-120.
  9. 孫彤, 王曙光, 吴飛雪. 復方守宫散治療腫瘤惡病質的臨床硏究. 安徽中醫學院學報, 2003;22(6):19.
  10. 蔡紅兵, 羅榮城, 楊傳標. 補中益氣湯治療癌症食欲不振振-惡病質綜合症30例療效觀察. 新中醫, 2003;35(3):25.
  11. 豊哲, 王大偉, 黃有榮, 陳鋒, 劉汝專, 安連生, 王銀山. 蔘苓白朮散方合四物湯加味改善轉移性骨腫瘤患者生存質量的近期臨床觀察. 廣西中醫藥, 2006;29(4):10-12.
  12. 姚勇偉, 劉云霞. 益氣健脾方聯合甲地孕酮對晚期癌症病 人生存質量的影響. 中國中醫藥科技. 2007;14(2):133.
  13. 胡文雷, 王建中. 蔘芪膠棗湯治療晚期肺癌惡病質30例近期療效觀察. 浙江中醫藥大學學報. 2007;31(2):194-195.
  14. 張廣信, 馬秋波. 扶正降逆顆粒對惡性腫瘤患者生存質量臨床硏究. 河北中醫, 2007;29(3):220-221.
  15. 陳捷. 枳朴六君子湯加味治療癌症食欲不振-惡病質綜合症56例. 陜西中醫, 2007;28(9):1182-1183.
  16. 羅定新, 陳銳深. 歸脾湯抗晚期癌症慢性消耗30例臨床硏究. 新中醫, 2008;40(1):24-25.
  17. 陳云鶯, 陳乃杰, 吴丹紅, 賴義勤. 蔘笭白朮散治療晩期癌症惡病質的臨床觀察. 福建中醫藥. 2008;39(4):7-8.
  18. 匡唐洪 劉云霞 姚勇偉. 益氣養陰湯治療晩期肺癌惡病質60例療效觀察. 浙江中醫雜誌. 2009;44(6):421-422.
  19. Ministary of health and welfare. National nutrition survey report. 2008.
  20. Grant M. Ropka ME. Alterations in nutrition. in McCorkle R. Grant M. Frank Stromborg M. Baird (Eds).S.B. Cancer Nursing, a comprehensive textbook. 2nd ed. Philadelphia:london Saunders. 1996.
  21. Kim Y.O. Han B. Association of Nutritional Status with Clinical Outcome of Stomach Cancer Patients. J Korean Soc Food Sci Nutr. 2000;29(6): 1185-1189.
  22. Burtis G. Caviw J. Martin S. Applied nutrition and diet therapy. Philadelphia:W.B. saunder Company. 1988:484-487.
  23. Rivadeneria DE. Denis E. Thomas JF. Micheael DL. John MD. Nutritional support of the cancer patients. CA Cancer J Clin. 1998;48:69-80. https://doi.org/10.3322/canjclin.48.2.69
  24. Shils ME. Olson JA. Shike M. Modern nutrition in health and disease. Philadephia:Lea&Feriger. 1994:1319-1326.
  25. McWhirter JP. Pennington CR. Incidence and recognition of malnutrition in hospital. BMJ. 1994;308:945-948. https://doi.org/10.1136/bmj.308.6934.945
  26. Kim EK. Yang YH. Choi SM. Nutritional Status of Cancer Patients upon Admission. J Korean Nurses Association. 1999;29(2):271-280.
  27. 黃琦, 江志偉, 黎介壽. 癌性惡病質的藥物治療與營養支持. 腸外與腸內營養. 2004;11(60):377-379.
  28. 趙景芳, 尤健良. 中醫治療癌症惡液質的三要點. 江蘇中醫. 1998;19(11):18-19.
  29. 張永軍, 馬勝林, 張緩琴. 中醫藥防治腫瘤惡病質的作用. 實用腫瘤雜誌. 2008;22(4):373-375.