Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
권호 표지
DOI QR코드

DOI QR Code

An Efficient Synthesis of trans-N-{2-[4-(2-Methoxyphenyl)piperazinyl]ethyl}-N-(2-pyridyl)-N-(4-tosyloxymethylcyclohexane)carboxamide, A Precursor of [18F]Mefway for Imaging 5-HT1A Receptor

  • Choi, Jae-Yong (Department of Nuclear Medicine, Yonsei University College of Medicine, Gangnam Severance Hospital) ;
  • Kim, Chul-Hoon (Department of Pharmacology, Brain Research Institute, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine) ;
  • Kim, Jung-Young (Molecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences) ;
  • Ha, Hyun-Joon (Department of Chemistry and Protein Research Center for Bio-Industry, Hankuk University of Foreign Studies) ;
  • Ryu, Young-Hoon (Department of Nuclear Medicine, Yonsei University College of Medicine, Gangnam Severance Hospital)
  • Received : 2010.02.16
  • Accepted : 2010.06.07
  • Published : 2010.08.20
Download PDF
⟨ Previous Next ⟩

Abstract

Keywords

References

  1. Fletcher, A.; Cliffe, I. A.; Dourish, C. T. TIPS 1993, 14, 441-448.
  2. Saxena, P. R. Pharmacol Ther.1995, 66, 339-368. https://doi.org/10.1016/0163-7258(94)00005-N
  3. Cliffe, I. A. Nucl Med Biol. 2000, 27, 441-447. https://doi.org/10.1016/S0969-8051(00)00109-8
  4. Dileep Kumar, J. S.; John Mann, J. Drug Discovery Today 2007, 12, 748-756. https://doi.org/10.1016/j.drudis.2007.07.008
  5. Grasby, P. M.; Bench, C. Current Opinion in Psychiatry 1997, 10, 73-78. https://doi.org/10.1097/00001504-199703000-00003
  6. Rabiner, E. A.; Bhagwager, Z.; Gunn, R. N.; Sargent, P. A.; Bench, C. J.; Cowen, P. J.; Grasby, P. M. Am. J. Psychiatry 2001, 158, 2080-2082. https://doi.org/10.1176/appi.ajp.158.12.2080
  7. Rabiner, E. A.; Gunn, R. N.; Wilkins, M. R.; Sedman, E.; Grasby, P. M. J. Psychopharmacol 2002, 16, 195-199. https://doi.org/10.1177/026988110201600301
  8. Pike, V. W.; McCarron, J. A.; Hume, S. P.; Ashworth, S.; Opacka-Juffry, J.; Osman, S.; Lammertsma, A. A.; Poole, K. G.; Fletcher, A.; White, A. C.; Cliffe, I. A. Med. Chem. Res. 1995, 5, 208-277.
  9. Oh, S. J.; Ha, H.-J.; Chi, D. Y.; Lee, H. K. Curr. Med. Chem. 2001, 8, 999-1034. https://doi.org/10.2174/0929867013372599
  10. Emerit, M. B.; El Mestikawy, S.; Gozlan, H.; Rouot, B.; Hamon, M. Biochem. Pharmacol. 1990, 39, 7-18. https://doi.org/10.1016/0006-2952(90)90642-X
  11. Mathis, C. A.; Huang, Y.; Simpson, N. R. J. Labelled Compd. Radipharm. 1997, 40, 563-564.
  12. Fletcher, A.; Bill, D. J.; Cliffe, I. A.; Foster, E. A.; Jones, D.; Reilly, Y. Br. J. Pharmacol.1993, 112, 91.
  13. Lang, L.; Jagoda, E.; Schmall, B.; Vuong, B.-K.; Adams, R.; Nelson, D. L.; Carson, R. E.; Eckelman, W. C. J. Med. Chem. 1999, 42, 1576-1586. https://doi.org/10.1021/jm980456f
  14. Pike, V. W.; Halldin, C.; Wikstrom, H.; Marchais, S.; McCarron, J. A.; Sandell, J.; Nowicki, B.; Swahn, C.-G.; Osman, S.; Hume, S. P.; Constantinou, M.; Andree, B.; Farde, L. Nucl. Med. Biol. 2000, 27, 449-455. https://doi.org/10.1016/S0969-8051(00)00110-4
  15. Lang, L.; Jagoda, E.; Ma, Y.; Sassaman, M. B.; Eckelman, W. C. Bioorg. Med. Chem. 2006, 14, 3737-3748. https://doi.org/10.1016/j.bmc.2006.01.064
  16. Marchais, S.; Nowicki, B.; Wikstrom, H.; Brennum, L. T.; Halldin, C.; Pike, V. W. Bioorg. Med. Chem. 2001, 9, 695-702. https://doi.org/10.1016/S0968-0896(00)00287-X
  17. Saigal, N.; Pichika, R.; Easwaramoorthy, B.; Collins, D.; Christian, B. T.; Shi, B.; Narayanan, T. K.; Potkin, S. G.; Mukherjee, J. J. Nucl. Med. 2006, 47, 1697-1706.

Cited by

  1. module vol.56, pp.12, 2013, https://doi.org/10.1002/jlcr.3067
  2. Synthesis and evaluation of mefway analogs as ligands for serotonin 5HT1A receptors vol.24, pp.4, 2015, https://doi.org/10.1007/s00044-014-1238-z