한국식품위생안전성학회지 (Journal of Food Hygiene and Safety)

  • 제25권1호
  • /
  • Pages.36-42
  • /
  • 2010
  • /
  • 1229-1153(pISSN)
  • /
  • 2465-9223(eISSN)
한국식품위생안전성학회 (The Korean Society of Food Hygiene and Safety)
권호 표지

Polyamide 조리기구로부터 Ethylenediamine 및 Hexamethylenediamine의 이행에 관한 연구

A Study on Migration of Ethylenediamine and Hexamethylenediamine from Polyamide Utensils

  • 엄미옥 (식품의약품안전청 첨가물기준과) ;
  • 곽인신 (식품의약품안전평가원 첨가물포장과) ;
  • 윤예정 (식품의약품안전평가원 위해영향연구팀) ;
  • 전대훈 (식품의약품안전청 첨가물기준과) ;
  • 최현철 (식품의약품안전청 검사제도과) ;
  • 김형일 (식품의약품안전평가원 첨가물포장과) ;
  • 성준현 (식품의약품안전평가원 첨가물포장과) ;
  • 박나영 (식품의약품안전청 첨가물기준과) ;
  • 김소희 (식품의약품안전평가원 첨가물포장과) ;
  • 이영자 (식품의약품안전청 첨가물기준과)
  • Eom, Mi-Ok (Food Additive Standards Division, Korea Food and Drug Administration) ;
  • Kwak, In-Shin (Food Additives and Packages Division, National Institute of Food and Drug Safety Evaluation) ;
  • Yoon, Hae-Jung (Health Effects Analysis Team, Korea Food and Drug Administration) ;
  • Jeon, Dae-Hoon (Food Additive Standards Division, Korea Food and Drug Administration) ;
  • Choi, Hyun-Chul (Laboratory Audit and Policy Division, Korea Food and Drug Administration) ;
  • Kim, Hyung-Il (Food Additives and Packages Division, National Institute of Food and Drug Safety Evaluation) ;
  • Sung, Jun-Hyun (Food Additives and Packages Division, National Institute of Food and Drug Safety Evaluation) ;
  • Park, Na-Young (Food Additive Standards Division, Korea Food and Drug Administration) ;
  • Kim, So-Hee (Food Additives and Packages Division, National Institute of Food and Drug Safety Evaluation) ;
  • Lee, Young-Ja (Food Additive Standards Division, Korea Food and Drug Administration)
  • 투고 : 2009.08.31
  • 심사 : 2010.01.14
  • 발행 : 2010.03.31
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초록

식품유사용매 중 EDA 및 HMDA 분석법을 확립하고, 국내유통 재질 조리기구 124건에 대하여 식품유사용매별 이행량을 조사하였다. EDA 및 HMDA를 ethyl chloroformate로 디우레탄 유도체화한 후 GC/FID로 정량 또는 GC/MS로 확인하였다. 확립된 분석방법은 EDA 및 HMDA 각각에 대하여 LOD $0.3\;{\mu}g/mL$ 및 $0.1\;{\mu}g/mL$이었으며, 상판계수($r^2$) 0.999이상의 직선성 및 식품유사용매별로 88% 이상의 회수율을 확인할 수 있었다. 확립된 정량분석방법을 적용하여 식품유사용매별 이행량을 조사한 결과, EDA는 식품유사용매로 물을 사용한 경우 2품목에서만 각각 $1.31\;{\mu}g/mL$ 및 $2.06\;{\mu}g/mL$ 수준으로 검출되었으며, 나머지는 모두 불검출이었다. HMDA는 식품유사용매로 20% 에탄올을 사용한 경우 3 품목에서 $0.27{\sim}0.93\;{\mu}g/mL$, n-헵탄을 사용한 경우 10 품목에서 $0.26{\sim}0.44\;{\mu}g/mL$으로 검출되었으며, 나머지는 모두 불검출이었다. 본 연구에서 확인된 이행량은 유럽연합의 EDA 및 HMDA 각각의 이행기준인 $12\;{\mu}g/mL$ 및 $2.4\;{\mu}g/mL$과 비교 시 매우 낮은 수준이었다.

The method for the determination of ethylenediamine (EDA) and hexamethylenediamine (HMDA) in food simulants was developed, and migration amounts of these compounds was monitored for 124 polyamide (PA) utensils. The diurethane derivatives of EDA and HMDA, which produced by reaction with ethyl chloroformate, were analyzed by using gas chromatograph (GC)/flame ionization detector (FID) and GC/mass spectrometer (MS). The developed method was validated with $0.3\;{\mu}g/mL$ of limit of detection (LOD) for EDA and $0.1\;{\mu}g/mL$ of LOD for HMDA, > 0.999 of linearity($r^2$) and > 88% of recovery. The EDA was detected 1.31 and $02.06\;{\mu}g/mL$ for 2 samples in water. The HMDA was detected $0.29\;-\;0.93\;{\mu}g/mL$ for 3 samples in 20% ethanol and $0.26\;-\;0.44\;{\mu}g/mL$ for 10 samples in n-heptane. These migration levels were below the specific migration limits (SML) of $12\;{\mu}g/mL$ and $2.4\;{\mu}g/mL$ for EDA and HMDA established in EU.

키워드

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