Analytical Science and Technology (분석과학)

The Korean Society of Analytical Sciences (한국분석과학회)
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Analysis of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in urine with certified reference material

인증표준물질(CRM)을 이용한 소변 중 대마 대사체 분석법 평가

  • Ko, Beom-Jun (Drug Aanlysis Laboratory, Supreme Prosecutors' Office) ;
  • Kim, Jin-Young (Drug Aanlysis Laboratory, Supreme Prosecutors' Office) ;
  • Kim, Jong-Sang (Department of Quality Management, Korea Institute of Construction Materials) ;
  • Lee, Jeong-Jik (Department of Quality Management, Korea Institute of Construction Materials) ;
  • Cheong, Jae-Chul (Drug Aanlysis Laboratory, Supreme Prosecutors' Office) ;
  • Suh, Sung-Ill (Drug Aanlysis Laboratory, Supreme Prosecutors' Office) ;
  • In, Moon-Kyo (Drug Aanlysis Laboratory, Supreme Prosecutors' Office)
  • Received : 2009.10.19
  • Accepted : 2010.01.18
  • Published : 2010.02.25
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Abstract

For the evaluation of our laboratory's 11-nor-${\Delta}^9$-tetrahydrocannabinol-9-carboxylic acid (THCCOOH) urinalysis test, THCCOOH urinalysis test was carried out with Certified Reference Material (CRM). The used CRM was THCCOOH in freeze-dried urine produced by NIST as Standard Reference Material 1507b. Comparing the estimated value of our laboratory with CRM, the results was coincided in the confidence level of approximately 95%.

대검찰청 마약감식실은 대마 흡연여부를 판별하는 수단인 소변 중 대마 대사체 성분 분석법 에 대한 신뢰도 평가를 위하여 인증표준물질을 이용한 시험을 실시하였다. 시험에 사용된 인증표준물질은 미국 NIST에서 판매하는 Standard Reference Material 1507b로, 11-nor-${\Delta}^9$-tetrahydrocannabinol-9-carboxylic acid (THCCOOH)가 함유된 냉동 건조 소변이었다. NIST에서 구매한 인증표준물질의 농도값과 실험실에서 측정한 농도값을 비교 평가해 본 결과, 약 95% 신뢰수준에서 일치하였다.

Keywords

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