생명과학회지 (Journal of Life Science)

  • 제20권3호
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  • Pages.356-364
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  • 2010
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  • 1225-9918(pISSN)
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  • 2287-3406(eISSN)
한국생명과학회 (Korean Society of Life Science)
권호 표지
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춘천지역 모유 중 폴리브롬화디페닐메테르(PBDEs)의 이성체별 분포특성과 노출경로

Congener Specific Profiles and Exposure Pathways of Polybrominated Diphenyl Ethers (PBDEs) in Breast Milk of Chuncheon Area

  • We, Sung-Ug (Department of Environmental Engineering, Kyungnam University) ;
  • Baek, In-Cheon (Department of Environmental Engineering, Kyungnam University) ;
  • Park, Sang-Ah (Department of Environmental Engineering, Kyungnam University) ;
  • Kang, Seong-Hoon (Department of Environmental Engineering, Kyungnam University) ;
  • Cho, Yu-Jin (Department of Environmental Engineering, Kyungnam University) ;
  • Cho, Bong-Hui (Department of Environmental Engineering, Kyungnam University) ;
  • Yoon, Cho-Hee (Department of Environmental Engineering, Kyungnam University) ;
  • Kim, Ki-Ho (Center for Instrumental Analysis, Kyungnam University) ;
  • Min, Byung-Yoon (Department of Environmental Engineering, Kyungnam University)
  • 투고 : 2009.12.02
  • 심사 : 2010.03.04
  • 발행 : 2010.03.30
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초록

본 연구는 비교적 청정한 지역인 춘천시에 거주하는 일반인 모유 중 PBDEs의 노출 경로를 확인하기 위해 처음으로 시도된 연구이다. 본 연구지역의 모유 중 ${\sum}PBDEs$의 수준은 북아메리카지역에 비하여 낮은 수준이었으나 일부 아시아, 유럽국가와 유사하였다. 모유 내 PBDEs의 축적은 산모의 특성과 상관관계가 나타나지 않았으나, 상엽용 PBDEs 제품을 포함하여 여러 복합적 인자에 의하여 노출되고 있었으며, 식품 섭취와 같은 식이노출은 한국인에 있어 중요한 노출 경로의 하나로 판단되었다. 따라서 본 연구 결과는 한국인의 PBDEs 노출 경로 파악에 중요한 정보를 제공하여, 장차 PBDEs 및 관련 브롬계 난연제의 노출에 따른 인체 위해성 평가를 수행함에 있어 중요한 참고자료가 될 것이다. 또한, 한국 내의 PBDEs에 대한 인체노출 경로를 명확하게 하기 위한 연구는 계속적으로 이루어져야 할 것이다.

This study was carried out to investigate the exposure pathway of PBDEs in human breast milk collected from new mothers residing in Chuncheon, a comparatively clean area in Korea. The congeners of PBDE in 22 human breast milk samples were analyzed using a high resolution gas chromatography with a high resolution mass detector. The residue level of ${\sum}PBDEs$ was higher in primipara subjects than in multipara subjects (p<0.05). The levels in this study were similar to those of people in some Asian and European countries, but were lower than those of people in north America. In the congener profiles, BDE-47 (mean contribution=36.1%) was predominant, followed by BDE-153 (27%), BDE-99 (11.7%), BDE-100 (11.1%), BDE-28 (7.9%) and BDE-183 (3.5%). The sum of BDE-47 and BDE-153 accounted for more than 50% of ${\sum}PBDEs$ in most samples. BDE-47 was highly correlated with ${\sum}PBDEs$ (r=0.94, p<0.001). No strong trend was observed between PBDE levels and a number of key biological factors (women's age, weight, height and body mass index) examined in this study, however, weak correlations were observed in PBDE levels measured against dietary habits, particularly in fish consumption frequency. It seems that Korean people might be exposed to multiple sources including products of PBDEs, and particularly food resources.

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피인용 문헌

  1. Concentrations of PBDE Congeners in Breast Milk and Predictors of Exposure in Seoul Residents vol.37, pp.6, 2011, https://doi.org/10.5668/JEHS.2011.37.6.440