대한한의학회지 (The Journal of Korean Medicine)

  • 제31권1호
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  • Pages.130-137
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  • 2010
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  • 1010-0695(pISSN)
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  • 2288-3339(eISSN)
대한한의학회 (The Society of Korean Medicine)
권호 표지

족삼리-해계 전침치료가 정상인의 국소 뇌혈류에 미치는 영향 -Brain SPECT와 SPM을 이용하여-

Effect of ST 36-ST 41 Electro-acupuncture on Regional Cerebral Blood Flow in Normal Volunteers Evaluated by $^{99m}Tc$-ECD SPECT

  • 문상관 (경희대학교 한의과대학 제2내과학교실) ;
  • 민인규 (경희대학교 한의과대학 제2내과학교실) ;
  • 박성욱 (경희대학교 한의과대학 제2내과학교실) ;
  • 정우상 (경희대학교 한의과대학 제2내과학교실) ;
  • 박정미 (경희대학교 한의과대학 제2내과학교실) ;
  • 고창남 (경희대학교 한의과대학 제2내과학교실) ;
  • 조기호 (경희대학교 한의과대학 제2내과학교실) ;
  • 배형섭 (경희대학교 한의과대학 제2내과학교실) ;
  • 김영석 (경희대학교 한의과대학 제2내과학교실) ;
  • 김덕윤 (경희대학교 의과대학 핵의학교실)
  • Moon, Sang-Kwan (Dept. of Cardiovascular and Neurologic Diseases (Steroke, Center), College of Oriental Medicine, Kyung Hee Univ.) ;
  • Min, In-Kyu (Dept. of Cardiovascular and Neurologic Diseases (Steroke, Center), College of Oriental Medicine, Kyung Hee Univ.) ;
  • Park, Sung-Uk (Dept. of Cardiovascular and Neurologic Diseases (Steroke, Center), College of Oriental Medicine, Kyung Hee Univ.) ;
  • Jung, Woo-Sang (Dept. of Cardiovascular and Neurologic Diseases (Steroke, Center), College of Oriental Medicine, Kyung Hee Univ.) ;
  • Park, Jung-Mee (Dept. of Cardiovascular and Neurologic Diseases (Steroke, Center), College of Oriental Medicine, Kyung Hee Univ.) ;
  • Ko, Chang-Nam (Dept. of Cardiovascular and Neurologic Diseases (Steroke, Center), College of Oriental Medicine, Kyung Hee Univ.) ;
  • Cho, Ki-Ho (Dept. of Cardiovascular and Neurologic Diseases (Steroke, Center), College of Oriental Medicine, Kyung Hee Univ.) ;
  • Bae, Hyung-Sup (Dept. of Cardiovascular and Neurologic Diseases (Steroke, Center), College of Oriental Medicine, Kyung Hee Univ.) ;
  • Kim, Young-Suk (Dept. of Cardiovascular and Neurologic Diseases (Steroke, Center), College of Oriental Medicine, Kyung Hee Univ.) ;
  • Kim, Deok-Yoon (Dept. of Nuclear Medicine, College of Medicine, Kyung Hee Univ.)
  • 투고 : 2009.08.12
  • 심사 : 2009.10.14
  • 발행 : 2010.01.30
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초록

Objectives: So far it has been reported that acupuncture increases cerebral blood supply and stimulates the functional activity of brain nerve cells. Previous studies have demonstrated that frequently used electro-acupuncture (EA) therapies for stroke increased regional cerebral blood flow (rCBF) in normal volunteers. Though ST 36-ST 41 EA is another prevailing therapy for stroke, there had been no report about its effect on rCBF. This study was to evaluate the effect of ST 36-ST 41 EA on rCBF in normal volunteers using single photon emission computed tomography (SPECT) and statistical parametric mapping (SPM). Methods: In the resting state, $^{99m}Tc$-ECD brain SPECT scans were performed on 10 normal volunteers (5 males, 5 female, mean age $23.6{\pm}0.5$ years). On the other study day, 7 days after the resting examination, 15 minutesEA were applied at ST 36 and ST 41 on the right side of the subjects. Immediately after ST36-ST41 EA, the second SPECT images were obtained in the same manner as the resting state. Significant increases and decreases of rCBF after EA were estimated by comparing their SPECT images with those of the resting state using paired t statistics at every voxel, which were analyzed by SPM with a threshold of p = 0.01, uncorrected (extent threshold: k=100 voxels). Results: EA applied at the right ST36-ST41 significantly increased rCBF in the right inferior parietal lobule (Brodmann area [BA] 40), right retrosubicular area (BA 48), left inferior parietal lobule (BA 40), left middle temporal gyrus (BA 21), left fusiform gyrus (BA 37), left inferior parietal lobule (BA 39), left inferior temporal gyrus (BA 20), and left somatosensory association cortex (BA 7). However, right ST36-ST41 EA significantly decreased rCBF in the right parahippocampal gyrus (BA 35), right cerebellum, left frontopolar area (BA 10), left orbitofrontal area (BA 11), left dorsolateral prefrontal cortex (BA 9), and left dorsal anterior cingulate cortex (BA 32). Conclusions: These results demonstrate that rightST36-ST41 EA increased rCBF prominently in both inferior parietal lobule (BA 40) and right retrosubicular area (BA 48), which suggest that there be correlation between specific EA and corresponding rCBF.

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참고문헌

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