대한한의학회지 (The Journal of Korean Medicine)

  • 제31권1호
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  • Pages.81-92
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  • 2010
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  • 1010-0695(pISSN)
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  • 2288-3339(eISSN)
대한한의학회 (The Society of Korean Medicine)
권호 표지

곡지, 족삼리 침자극이 뇌활성화에 미치는 영향에 대한 뇌기능적 자기공명영상을 이용한 연구

Functional MRI Study of Changes in Brain Activity by Manual Acupuncture at LI11 or ST36

  • 조승연 (경희대학교 동서신의학병원 중풍뇌질환센터 한방내과) ;
  • 장건호 (경희대학교 동서신의학병원 영상의학과) ;
  • 박성욱 (경희대학교 동서신의학병원 중풍뇌질환센터 한방내과) ;
  • 정우상 (경희대학교 경희의료원 한방병원 한의과대학 심계내과학 교실) ;
  • 문상관 (경희대학교 경희의료원 한방병원 한의과대학 심계내과학 교실) ;
  • 고창남 (경희대학교 동서신의학병원 중풍뇌질환센터 한방내과) ;
  • 조기호 (경희대학교 경희의료원 한방병원 한의과대학 심계내과학 교실) ;
  • 김영석 (경희대학교 경희의료원 한방병원 한의과대학 심계내과학 교실) ;
  • 배형섭 (경희대학교 동서신의학병원 중풍뇌질환센터 한방내과) ;
  • 박정미 (경희대학교 동서신의학병원 중풍뇌질환센터 한방내과)
  • Cho, Seung-Yeon (Department of Cardiovascular & Neurologic Disease(Stroke Center), East-West Neo Medical Center, College of Korean Medicine, Kyung Hee University) ;
  • Jahng, Geon-Ho (Department of Radiology, East-West Neo Medical Center, School of Medicine, Kyung Hee University) ;
  • Park, Seong-Uk (Department of Cardiovascular & Neurologic Disease(Stroke Center), East-West Neo Medical Center, College of Korean Medicine, Kyung Hee University) ;
  • Jung, Woo-Sang (Department of Cardiovascular & Neurologic Diseases(Stroke center), Hospital of Korean Medicine, Kyung Hee Medical Center, College of Korean Medicine, Kyung Hee University) ;
  • Moon, Sang-Kwan (Department of Cardiovascular & Neurologic Diseases(Stroke center), Hospital of Korean Medicine, Kyung Hee Medical Center, College of Korean Medicine, Kyung Hee University) ;
  • Gho, Chang-Nam (Department of Cardiovascular & Neurologic Disease(Stroke Center), East-West Neo Medical of Korean Medicine, Kyung Hee University Center) ;
  • Cho, Ki-Ho (Department of Cardiovascular & Neurologic Diseases(Stroke center), Hospital of Korean Medicine, Kyung Hee Medical Center, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Young-Suk (Department of Cardiovascular & Neurologic Diseases(Stroke center), Hospital of Korean Medicine, Kyung Hee Medical Center, College of Korean Medicine, Kyung Hee University) ;
  • Bae, Hyung-Sup (Department of Cardiovascular & Neurologic Disease(Stroke Center), East-West Neo Medical Center, College of Korean Medicine, Kyung Hee University) ;
  • Park, Jung-Mi (Department of Cardiovascular & Neurologic Disease(Stroke Center), East-West Neo Medical Center, College of Korean Medicine, Kyung Hee University)
  • 투고 : 2009.07.24
  • 심사 : 2009.08.31
  • 발행 : 2010.01.30
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초록

Objectives: The objective of this study was to assess bra in activation and difference by LI11 or ST36 acupuncture stimulation using functional MRI (fMRI). Methods: A total of 10 healthy right-handed volunteers were studied. LI11 acupuncture and ST36 acupuncture stimulations were applied in order on the left. The block design paradigm of RARARA was used for the task, with R representing rest and A representing stimulation, and each period lasted 30 seconds. fMRI data were analyzed using SPM2. Results: The left LI11 acupuncture stimulation activated both sides of the inferior parietal lobule, the left side of the extra-nuclear, culmen and inferior semi-lunar lobules. On the right side, the nodule and midbrain regions were activated by the left LI11 acupuncture stimulation. The left ST36 acupuncture stimulation activated the right side of the superior frontal gyrus, middle frontal gyrus, superior parietal lobule, inferior semi-lunar lobule and pyramis. On the left side, the sub-gyral, middle temporal gyrus, fusiform gyrus, supramarginal gyrus, extra-nuclear, cingulate gyrus and fastigium regions were activated by the left ST36 acupuncture stimulation. Besides, both sides of the paracentral lobule, inferior parietal lobule, culmen, cerebellar tonsil and midbrain regions were activated. Conclusions: In conclusion, brain signal activation patterns according to acupoints were observed to differ, and ST36 acupuncture stimulation activated more regions than LI11. It is supposed that LI11 and ST36 acupuncture stimulations have an influence on motor function and sensory aphasia, and these stimulations thus represent potential for ocular motor dysfunction, discriminative touch or position sense disorder. Moreover, ST36 acupuncture stimulation activated the cingulate gyrus of the limbic system, so it seems to have an influence over autonomic functions.

키워드

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