Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Aldose Reductase Inhibitory Activity of Scrophularia Species

  • Kim, Hye-Min (Department of Applied Plant Science, Chung-Ang University) ;
  • Han, Saem (Department of Applied Plant Science, Chung-Ang University) ;
  • Lee, Yeon-Sil (Center for Efficacy Assessment and Development of Functional Foods and Drugs, Hallym University) ;
  • Chung, Jae-Min (Department of Plant Resources Conservation, Korea National Arboretum) ;
  • Lee, Sang-Hyun (Department of Applied Plant Science, Chung-Ang University)
  • Received : 2010.01.26
  • Accepted : 2010.03.17
  • Published : 2010.03.31
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Abstract

Effects of the species Scrophularia takesimensis, S. kakudensis, S. boreali-koreana, and S. buergeriana on rat lens aldose reductase inhibition have been investigated. Among them, the extracts of S. kakudensis and S. boreali-koreana were exhibited good inhibitory potencies compared with those of S. takesimensis and S. buergeriana. The $IC_{50}$ values of the aerial part extracts from S. kakudensis and S. boreali-koreana were demonstrated 0.46 and 0.35 mg/ml, respectively.

Keywords

References

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